Journal of the Korean Crystal Growth and Crystal Technology (한국결정성장학회지)

The Korea Association of Crystal Growth (한국결정성장학회)
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Antibacterial properties of traditional ceramic glazes containing copper oxide

산화구리를 함유하는 전통 세라믹 유약의 항균특성에 관한 연구

  • Kim, Ung-Soo (Icheon Branch, Korea Institute of Ceramic Engineering and Technology) ;
  • Choi, Jung-Hoon (Icheon Branch, Korea Institute of Ceramic Engineering and Technology) ;
  • No, Hyung-Goo (Icheon Branch, Korea Institute of Ceramic Engineering and Technology) ;
  • Han, Kyu-Sung (Icheon Branch, Korea Institute of Ceramic Engineering and Technology) ;
  • Kim, Jin-Ho (Icheon Branch, Korea Institute of Ceramic Engineering and Technology) ;
  • Hwang, Kwang-Taek (Icheon Branch, Korea Institute of Ceramic Engineering and Technology)
  • 김응수 (한국세라믹기술원 도자융합기술센터) ;
  • 최정훈 (한국세라믹기술원 도자융합기술센터) ;
  • 노형구 (한국세라믹기술원 도자융합기술센터) ;
  • 한규성 (한국세라믹기술원 도자융합기술센터) ;
  • 김진호 (한국세라믹기술원 도자융합기술센터) ;
  • 황광택 (한국세라믹기술원 도자융합기술센터)
  • Received : 2019.11.11
  • Accepted : 2019.12.12
  • Published : 2019.12.31
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Abstract

Traditional ceramic glazes formulated with copper oxide (CuO) exhibited antibacterial properties on Staphylococcus aureus (Gram Positive) and Escherichia coli (Gram Negative). All the ceramic glazes containing CuO showed antibacterial behavior when fired in reducing atmosphere. However, some of copper glazes presented antibacterial behavior and had no antibacterial properties at all when sintered in an oxidizing atmosphere. To elucidate the antibacterial mechanism, ceramic glazes were studied for phase and microstructure analysis, dissolution behavior and surface zeta potential. Metallic copper was precipitated in the glaze layer when sintered in reducing atmosphere. Less than 0.05 ppm of Cu ion was dissolved from glazes. Ca ion was most dissolved among all the samples. Glaze surface was highly negatively charged when CuO was added over 3 wt.% regardless of the sintering atmosphere. The antibacterial behavior of ceramic glazes seemed to be directly related to the dissolution behavior of cations, but the antibacterial behavior of oxidized specimens was not explained by the dissolution behavior. Surface potential of ceramic glazes appeared to play an auxiliary role in antibacterial properties.

산화구리를 함유하는 전통 세라믹 유약은 황색포도상구균과 대장균에 대해 항균활성을 나타낸다. 환원 분위기에 소결한 모든 시편들은 황색포도상구균과 대장균에 대해 항균활성을 나타내나 산화분위기에서 소결한 일부 시편들만 황색포도상구균과 대장균에 대해 항균활성을 나타내었다. 산화구리를 함유하는 전통 세라믹 유약의 항균기작을 설명하기 위해 유약의 결정상, 미세구조, 이온용출, 표면 제타전위 분석을 실시하였다. 환원 분위기에서 소결한 시편들은 유약층에 Cu 입자들이 형성되는 것을 확인할 수 있다. Cu 용출량은 전체적으로 0.05 ppm 이하이며 가장 많이 용출되는 이온은 Ca 이었다. 산화구리를 3 wt.% 이상 첨가한 모든 시편들은 높은 음극의 표면 제타전위를 나타내었다. 세라믹 유약의 항균활성은 일반적으로 용출되는 양이온들과 연관되어 보이나 산화분위기에서 소결한 시편들의 대장균에 대한 항균활성은 직접적인 연관성이 나타나지 않는다. 세라믹 유약 시편의 표면 제타전위가 이온용출과 더불어 대장균에 대한 항균활성에 보조적 기여를 하는 것으로 보인다.

Keywords

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