DOI QR코드

DOI QR Code

Antibiotic sensitivity and resistance of bacteria from odontogenic maxillofacial abscesses

  • Kang, Sang-Hoon (Department of Oral and Maxillofacial Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Kim, Moon-Key (Department of Oral and Maxillofacial Surgery, National Health Insurance Service Ilsan Hospital)
  • 투고 : 2019.03.14
  • 심사 : 2019.04.08
  • 발행 : 2019.12.31

초록

Objectives: This study investigated the types and antibiotic sensitivity of bacteria in odontogenic abscesses. Materials and Methods: Pus specimens from 1,772 patients were collected from affected areas during incision and drainage, and bacterial cultures and antibiotic sensitivity tests were performed. The number of antibiotic-resistant bacteria was analyzed relative to the total number of bacteria that were tested for antibiotic susceptibility. Results: Bacterial cultures from 1,772 patients showed a total of 2,489 bacterial species, 2,101 gram-positive and 388 gram-negative. For penicillin G susceptibility tests, 2 out of 31 Staphylococcus aureus strains tested showed sensitivity and 29 showed resistance. For ampicillin susceptibility tests, all 11 S. aureus strains tested showed resistance. In ampicillin susceptibility tests, 46 out of 50 Klebsiella pneumoniae subsp. pneumoniae strains tested showed resistance. Conclusion: When treating odontogenic maxillofacial abscesses, it is appropriate to use antibiotics other than penicillin G and ampicillin as the first-line treatment.

키워드

참고문헌

  1. Robertson D, Smith AJ. The microbiology of the acute dental abscess. J Med Microbiol 2009;58(Pt 2):155-62. https://doi.org/10.1099/jmm.0.003517-0
  2. Sobottka I, Wegscheider K, Balzer L, Böger RH, Hallier O, Giersdorf I, et al. Microbiological analysis of a prospective, randomized, double-blind trial comparing moxifloxacin and clindamycin in the treatment of odontogenic infiltrates and abscesses. Antimicrob Agents Chemother 2012;56:2565-9. https://doi.org/10.1128/AAC.06428-11
  3. Walia IS, Borle RM, Mehendiratta D, Yadav AO. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. J Maxillofac Oral Surg 2014;13:16-21. https://doi.org/10.1007/s12663-012-0455-6
  4. Seppänen L, Lauhio A, Lindqvist C, Suuronen R, Rautemaa R. Analysis of systemic and local odontogenic infection complications requiring hospital care. J Infect 2008;57:116-22. https://doi.org/10.1016/j.jinf.2008.06.002
  5. Opitz D, Camerer C, Camerer DM, Raguse JD, Menneking H, Hoffmeister B, et al. Incidence and management of severe odontogenic infections-a retrospective analysis from 2004 to 2011. J Craniomaxillofac Surg 2015;43:285-9. https://doi.org/10.1016/j.jcms.2014.12.002
  6. Rega AJ, Aziz SR, Ziccardi VB. Microbiology and antibiotic sensitivities of head and neck space infections of odontogenic origin. J Oral Maxillofac Surg 2006;64:1377-80. https://doi.org/10.1016/j.joms.2006.05.023
  7. Sweeney LC, Dave J, Chambers PA, Heritage J. Antibiotic resistance in general dental practice--a cause for concern? J Antimicrob Chemother 2004;53:567-76. https://doi.org/10.1093/jac/dkh137
  8. Dahlen G. Microbiology and treatment of dental abscesses and periodontal-endodontic lesions. Periodontol 2000 2002;28:206-39. https://doi.org/10.1034/j.1600-0757.2002.280109.x
  9. Bertossi D, Barone A, Iurlaro A, Marconcini S, De Santis D, Finotti M, et al. Odontogenic orofacial infections. J Craniofac Surg 2017;28:197-202. https://doi.org/10.1097/SCS.0000000000003250
  10. Stefanopoulos PK, Kolokotronis AE. The clinical significance of anaerobic bacteria in acute orofacial odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:398-408. https://doi.org/10.1016/j.tripleo.2004.01.016
  11. Lewis MA, MacFarlane TW, McGowan DA. A microbiological and clinical review of the acute dentoalveolar abscess. Br J Oral Maxillofac Surg 1990;28:359-66. https://doi.org/10.1016/0266-4356(90)90032-G
  12. Lee YQ, Kanagalingam J. Bacteriology of deep neck abscesses: a retrospective review of 96 consecutive cases. Singapore Med J 2011;52:351-5.
  13. Sayd S, Vyloppilli S, Kumar K, Subash P, Kumar N, Raseel S. Comparison of the efficacy of amoxicillin-clavulanic acid with metronidazole to azithromycin with metronidazole after surgical removal of impacted lower third molar to prevent infection. J Korean Assoc Oral Maxillofac Surg 2018;44:103-6. https://doi.org/10.5125/jkaoms.2018.44.3.103