여성건강간호학회지 (Women's Health Nursing)

  • 제25권4호
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  • Pages.365-378
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  • 2019
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  • 3022-7666(pISSN)
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  • 3022-8247(eISSN)
한국여성건강간호학회 (Korean Society of Women Health Nursing)
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장액성 난소암 환자의 유전성 난소암에 대한 지식 및 불안정도

Knowledge and Anxiety Related to Hereditary Ovarian Cancer in Serous Ovarian Cancer Patients

  • 이상희 (연세대학교 간호대학) ;
  • 이향규 (연세대학교 간호대학 김모임 간호학연구소) ;
  • 임명철 (국립암센터 자궁난소암센터) ;
  • 김수 (연세대학교 간호대학 김모임 간호학연구소)
  • Lee, Sang Hee (College of Nursing, Yonsei University) ;
  • Lee, Hyangkyu (College of Nursing, Mo-Im Kim Nursing Research Institute, Yonsei University) ;
  • Lim, Myong Cheol (Uterine Ovarian Cancer Center, National Cancer Center) ;
  • Kim, Sue (College of Nursing, Mo-Im Kim Nursing Research Institute, Yonsei University)
  • 투고 : 2019.08.08
  • 심사 : 2019.11.25
  • 발행 : 2019.12.20
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초록

Purpose: The awareness of hereditary breast and ovarian cancer (HBOC) and BRCA testing is increasing in Korea. Compared to the sizable research on HBOC knowledge among breast cancer women, studies in the ovarian cancer population are limited. This paper aimed to investigate the level of knowledge of hereditary ovarian cancer and anxiety in women diagnosed with serous ovarian cancer in Korea and determine differences in the knowledge and anxiety according to whether genetic testing was undertaken and whether BRCA1 or BRCA2 mutations were present. Methods: Using a descriptive research design, a cross-sectional survey was conducted on 100 women diagnosed with serous ovarian cancer at N hospital in Gyeonggi-do, Korea, from July to November 2018. The collected data were analyzed by descriptive statistics, independent t-tests, one-way analysis of variance, and Pearson's correlation coefficient using the SPSS 21.0 program. Results: The hereditary ovarian cancer-related knowledge score was mid-level (mean score 8.90±3.29 out of a total of 17), as was the state anxiety level was mid-level (mean score 47.96±3.26 out of possible score range of 20-80). Genetic knowledge of hereditary ovarian cancer was associated with age, education, occupation, genetic counseling, and BRCA mutations. There were no statistically significant factors related to anxiety and there were no statistically significant correlations between knowledge level and anxiety. Conclusion: More comprehensive education on gene-related cancer is needed for ovarian cancer patients, especially for items with low knowledge scores. A genetic counseling protocol should be developed to allow more patients to alleviate their anxiety through genetic counseling.

키워드

참고문헌

  1. Kim SC. Recent advances in ovarian cancer treatment. Journal of the Korean Medical Association. 2016;59(3):164-166. https://doi.org/10.5124/jkma.2016.59.3.164
  2. Hanchette C, Zhang CH, Schwartz GG. Ovarian cancer incidence in the U.S. and toxic emissions from pulp and paper plants: a geospatial analysis. International Journal of Environmental Research and Public Health. 2018;15(8):E1619.
  3. Jung KW, Won YJ, Kong HJ, Lee ES; Community of Population-Based Regional Cancer Registries. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2015. Cancer Research and Treatment. 2018;50(2):303-316. https://doi.org/10.4143/crt.2018.143
  4. Korea Central Cancer Registry, National Cancer Center. Annual report of cancer statistics in Korea in 2016. Sejong: Ministry of Health and Welfare; 2018.
  5. Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, et al. High grade serous ovarian carcinomas originate in the fallopian tube. Nature Communications. 2017;8(1):1093. https://doi.org/10.1038/s41467-017-00962-1
  6. Bowtell DD. The genesis and evolution of high-grade serous ovarian cancer. Nature Reviews Cancer. 2010;10(11):803-808. https://doi.org/10.1038/nrc2946
  7. Kim HH. Precision Medicine and breast cancer. The Proceedings of KIEE. 2016;65(5):49-50.
  8. Son BH, Ahn SH, Lee MH, Park SK, Kim SW. Hereditary breast cancer in Korea: a review of the literature. Journal of Breast Cancer. 2008;11(1):1-9. https://doi.org/10.4048/jbc.2008.11.1.1
  9. Han SA, Kim SH, Kang EY, Ha TH, Kim JH, Yang EJ, et al. Evaluation of psychosocial impact and quality of life in BRCA mutation family. Journal of Genetic Medicine. 2010;7(1):67-77. https://doi.org/10.5734/JGM.2010.7.1.67
  10. Koehly LM, Peters JA, Kenen R, Hoskins LM, Ersig AL, Kuhn NR, et al. Characteristics of health information gatherers, disseminators, and blockers within families at risk of hereditary cancer: implications for family health communication interventions. American Journal of Public Health. 2009;99(12):2203-2209. https://doi.org/10.2105/AJPH.2008.154096
  11. Seo H, Yi M. A study genetic knowledge and anxiety in patients with breast cancer. Asian Oncology Nursing. 2017;17(3):151-157. https://doi.org/10.5388/aon.2017.17.3.151
  12. Yi M, Kim JH, Park EY, Kim JN, Yu ES. Focus group study on psychosocial distress of cancer patients. Korean Journal of Adult Nursing. 2010;22(1):19-30.
  13. Park YS, Park JS. Awareness and health belief of ovarian cancer among women in an urban area. Journal of the Korean Society of Maternal and Child Health. 2016;20(3):239-252. https://doi.org/10.21896/jksmch.2016.20.3.239
  14. Kinney AY, Croyle RT, Dudley WN, Bailey CA, Pelias MK, Neuhausen SL. Knowledge, attitudes, and interest in breast-ovarian cancer gene testing: a survey of a large African-American kindred with a BRCA1 mutation. Preventive Medicine. 2001;33(6):543-551. https://doi.org/10.1006/pmed.2001.0920
  15. Hughes C, Gomez-Caminero A, Benkendorf J, Kerner J, Isaacs C, Barter J, et al. Ethnic differences in knowledge and attitudes about BRCA1 testing in women at increased risk. Patient Education and Counseling. 1997;32(1-2):51-62. https://doi.org/10.1016/s0738-3991(97)00064-5
  16. Butow P, Meiser B, Price M, Bennett B, Tucker K, Davenport T, et al. Psychological morbidity in women at increased risk of developing breast cancer: a controlled study. Psycho-Oncology. 2005;14(3):196-203. https://doi.org/10.1002/pon.835
  17. Lindberg NM, Wellisch D. Anxiety and compliance among women at high risk for breast cancer. Annals of Behavioral Medicine. 2001;23(4):298-303. https://doi.org/10.1207/s15324796abm2304_9
  18. Coyne JC, Benazon NR, Gaba CG, Calzone K, Weber BL. Distress and psychiatric morbidity among women from high-risk breast and ovarian cancer families. Journal of Consulting and Clinical Psychology. 2000;68(5):864-874. https://doi.org/10.1037/0022-006X.68.5.864
  19. Choi KS, So HS, Tae YS, Eun Y, Suh SR, Lee WS, et al. The knowledge of hereditary breast cancer in Korean nurses. Journal of Korean Academic Society of Nursing Education. 2006;12(2):272-279.
  20. Kang E, Park SK, Kim KS, Choi DH, Nam SJ, Paik NS, et al. Communication with family members about positive BRCA1/2 genetic test results in Korean hereditary breast cancer families. Journal of Genetic Medicine. 2011;8(2):105-112. https://doi.org/10.5734/JGM.2011.8.2.105
  21. Erblich J, Brown K, Kim Y, Valdimarsdottir HB, Livingston BE, Bovbjerg DH. Development and validation of a breast cancer genetic counseling knowledge questionnaire. Patient Education and Counseling. 2005;56(2):182-191. https://doi.org/10.1016/j.pec.2004.02.007
  22. Spielberg CD, Gorsuch RL, Lushene R, Vagg PR, Jacobs GA. Manual for the state-trait anxiety inventory. Palo Alto: Consulting Psychologists Press; 1983.
  23. Kim JT. Relationship between static anxiety and social performance: based on Spielberger's STAI rule [master's thesis]. Seoul: Korea University; 1978. 81 p.
  24. Tranin AS, Masny A, Jenkins J. Genetics in oncology practice: cancer risk assessment. Pittsburgh: Oncology Nursing Society; 2003.
  25. Park SH, Lee SY. Exploring categories of health information users on the basis of illness attitude and health information seeking behavior on the internet. Korean Journal of Journalism & Communication Studies. 2011;55(4):105-133.
  26. Kim HJ. Genetic counseling in Korean Health Care System. Journal of Genetic Medicine. 2011;8(2):89-99. https://doi.org/10.5734/JGM.2011.8.2.89
  27. Kaiser AS, Ferris LE, Pastuszak AL, Llewellyn-Thomas H, Johnson JA, Conacher S, et al. The effects of prenatal group genetic counselling on knowledge, anxiety and decisional conflict: issues for nuchal translucency screening. Journal of Obstetrics and Gynaecology. 2002;22(3):246-255. https://doi.org/10.1080/01443610220130508
  28. Meiser B, Butow P, Friedlander M, Barratt A, Schnieden V, Watson M, et al. Psychological impact of genetic testing in women from high-risk breast cancer families. European Journal of Cancer. 2002;38(15):2025-2031. https://doi.org/10.1016/S0959-8049(02)00264-2
  29. Meiser B, Butow PN, Barratt AL, Schnieden V, Gattas M, Kirk J, et al. Long-term outcomes of genetic counseling in women at increased risk of developing hereditary breast cancer. Patient Education and Counseling. 2001;44(3):215-225. https://doi.org/10.1016/S0738-3991(00)00191-9

피인용 문헌

  1. Factors influencing posttraumatic growth in ovarian cancer survivors vol.29, pp.4, 2019, https://doi.org/10.1007/s00520-020-05704-6