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수정된 한글 연명의료계획서(Modified Korean Physician Order for Life-Sustaining Treatment, MK-POLST) 분석을 통한 호스피스 병동 환자의 의료 중재 항목별 선호도 및 충실도 조사

Preference and Performance Fidelity of Modified Korean Physician Order for Life-Sustaining Treatment (MK-POLST) Items in Hospice Patients with Cancer

  • 한지희 (경상대학교병원 내과) ;
  • 천혜숙 (경상대학교병원 간호부) ;
  • 김태희 (경상대학교병원 간호부) ;
  • 김록범 (경상대학교병원 권역심혈관센터) ;
  • 김정훈 (경상대학교병원 내과) ;
  • 강정훈 (경상대학교병원 내과)
  • Han, Ji Hee (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Chun, Hye Sook (Department of Nursing, Gyeongsang National University Hospital) ;
  • Kim, Tae Hee (Department of Nursing, Gyeongsang National University Hospital) ;
  • Kim, Rock Bum (Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital) ;
  • Kim, Jung Hoon (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kang, Jung Hun (Department of Internal Medicine, Gyeongsang National University Hospital)
  • 투고 : 2019.08.04
  • 심사 : 2019.11.11
  • 발행 : 2019.12.01

초록

목적: 호스피스 및 완화치료 환자 또는 임종단계 환자를 위한 연명 치료 결정에 관한 법안은 2016년에 제정되어 2018년 2월부터 시행 되었다. 이 법안의 취지와 내용은 미국의 POLST에 근거한다. 이 연구의 목적은 미국의 POLST를 변형하여 만든 MK-POLST를 호스피스 병동 환자들에게 적용을 한 뒤 각 항목에 대한 선호도 및 시행 일치율을 조사하는 것이다. 방법: 2017년 2월 1일부터 2019년 4월 30일까지 경상대학교병원의 부속 호스피스 병동의 모든 입원 환자의 MK-POLST에 대한 의무기록을 후향적으로 분석하였다. 결과: 총 387명의 연구대상자 중 295명의 환자가 MK-POLST를 작성했다. MK-POLST는 환자 자신이 133건(44.1%), 배우자가 84건(28.5 %), 자녀가 75건(25.4%) 작성했다. MK-POLST가 작성된 295 명의 환자 중 단 13명(4.4%)이 주사 영양제를 거부하였으며, 5명(1.7%)은 완화적 진정을 거부하였지만, 대다수인 288명(97.6%)이 심폐소생술 및 인공호흡기 치료를 원하지 않았고, 226명(76.9%)이 승압제 사용을 원하지 않았다. 인공호흡기, 심폐소생술 및 완화적 진정을 제외한 모든 MK-POLST 항목의 시행 일치율에 대한 Kappa 값은 낮았다. 결론: 호스피스 환자들은 심폐소생술, 인공호흡기 및 승압제 사용은 거부 했지만, 대조적으로 항생제, 주사 영양제 및 완화적 진정은 대다수 또는 절대적인 경우에 선호했다.

Purpose: The Act on Hospice and Palliative Care and Decisions on Life-sustaining Treatment for Patients at the End of Life was enacted in 2016 and has taken effect since 2018 February. The content of this act was based on Physician Orders for Life-Sustaining Treatment (POLST) in the United States and we modified it for terminal cancer patients registering hospice. The object of this study is to investigate preference and implementation rate for modified Korean POLST (MMK-POLST) items in hospice ward. Methods: From February 1, 2017 to April 30, 2019, medical records regarding MMK-POLST were retrospectively analyzed for all patients hospitalized in the hospice ward of Gyeongsang National University Hospital. Results: Of the eligible 387 total cohorts, 295 patients filled out MK-POLST. MK-POLST has been completed in 133 cases (44.1%) by the patient themselves, 84 cases (28.5%) by the spouse, and 75 cases (25.4%) by their children, respectively. While only 13 (4.4%) out of 295 MK-POLST completed patients refused the parenteral nutrition and 5 patients (1.7%) for palliative sedation, the absolute majority of 288 (97.6%) patients did not want cardiopulmonary resuscitation (CPR) and ventilators and 226 people (76.9%) for pressor medications. Kappa values for the matched strength of MK-POLST implementation were poor for all items except CPR, ventilators and palliative sedation. Conclusion: Hospice patients refused to conduct cardiopulmonary resuscitation, ventilators and pressor agents. In contrast, antibiotics, parenteral nutrition and palliative sedation were favored in the majority of patients.

키워드

참고문헌

  1. Ryu KH. Consideration on the Life-Sustaining Treatment Decision System. Legal Theory Prac Rev 2019;7:191-211. https://doi.org/10.30833/LTPR.2019.02.7.1.191
  2. The National Law Information Center [Internet]. Act on Decisions on Life-Sustaining Treatment for Patients in Hospice and Palliative Care or at the End of Life. Sejong: Korea Ministry of Government Legislation; c1997-2019. [cited 2019 Nov 07]. Available from: http://www.law.go.kr/lsInfoP.do?lsiSeq=180823#0000.
  3. Bomba PA, Kemp M, Black JS. POLST: An improvement over traditional advance directives. Cleve Clin J Med 2012;79:457-64. https://doi.org/10.3949/ccjm.79a.11098
  4. he National Law Information Center [Internet]. Enforcement Decree of the Act on Hospice and Palliative Care and Decisions on Life-Sustaining Treatment for Patients at the End of Life. Sejong: Korea Ministry of Government Legislation; c1997-2019. [cited 2019 Oct 22]. Available from: http://www.mohw.go.kr/react/al/sal0301vw.jsp?PAR_MENU_ID=04&MENU_ID=0403&CONT_SEQ=348830.
  5. Hickman SE, Nelson CA, Moss AH, Hammes BJ, Terwilliger A, Jackson A, et al. Use of the Physician Orders for Life-Sustaining Treatment (POLST) paradigm program in the hospice setting. J Palliat Med 2009;12:133-41. https://doi.org/10.1089/jpm.2008.0196
  6. Fromme EK, Zive D, Schmidt TA, Cook JN, Tolle SW. Association between Physician Orders for Life-Sustaining Treatment for Scope of Treatment and in-hospital death in Oregon. J Am Geriatr Soc 2014;62:1246-51. https://doi.org/10.1111/jgs.12889
  7. Schmidt TA, Zive D, Fromme EK, Cook JN, Tolle SW. Physician orders for life-sustaining treatment (POLST): lessons learned from analysis of the Oregon POLST Registry. Resuscitation 2014;85:480-5. https://doi.org/10.1016/j.resuscitation.2013.11.027
  8. An HJ, Jeon HJ, Chun SH, Jung HA, Ahn HA, Lee KH, et al. Feasibility Study of Physician Orders for Life-Sustaining Treatment for Patients with Terminal Cancer. Cancer Res Treat 2019;51:1632-8. https://doi.org/10.4143/crt.2019.009
  9. Kim JW. Completion rate of physician orders for life sustaining treatment (POLST) in patients with metastatic or recurrent cancer when suggested by physicians and attitudes toward end-of-life care [master's thesis]. Seoul: Korea Univ.; 2019. Korean.
  10. Keam B, Yun YH, Heo DS, Park BW, Cho CH, Kim S, et al. The attitudes of Korean cancer patients, family caregivers, oncologists, and members of the general public toward advance directives. Support Care Cancer 2013;21:1437-44. https://doi.org/10.1007/s00520-012-1689-z
  11. McHugh ML. Interrater reliability: the kappa statistic. Biochem Med (Zagreb) 2012;22:276-82. https://doi.org/10.11613/BM.2012.031
  12. Kong BH, An HJ, Kim HS, Ha SY, Kim IK, Lee JE, et al. Experience of advance directives in a hospice center. J Korean Med Sci 2015;30:151-4. https://doi.org/10.3346/jkms.2015.30.2.151
  13. Lee RY, Sathitratanacheewin S, Engelberg RA, Curtis J, Kross EK. POLST-Discordant Intensive Care Near the End of Life. B94 Addressing palliative and psychosocial needs among patients at end of life, their families, and the chronically critically ill. American Thoracic Society 2018 International Conference; 2018 May 18-23; San Diego (CA), USA. AJRCCM 2018:197:A4169.
  14. Bruera S, Chisholm G, Dos Santos R, Crovador C, Bruera E, Hui D. Variations in vital signs in the last days of life in patients with advanced cancer. J Pain Symptom Manage 2014;48:510-7. https://doi.org/10.1016/j.jpainsymman.2013.10.019
  15. Rhee C, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, et al. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA 2017;318:1241-9. https://doi.org/10.1001/jama.2017.13836
  16. Park HY, Kim YA, Sim JA, Lee J, Ryu H, Lee JL, et al. Attitudes of the General Public, Cancer Patients, Family Caregivers, and Physicians Toward Advance Care Planning: A Nationwide Survey Before the Enforcement of the Life-Sustaining Treatment Decision-Making Act. J Pain Symptom Manage 2019;57:774-82. https://doi.org/10.1016/j.jpainsymman.2018.12.332
  17. Kim YS, Song HN, Ahn JS, Koh SJ, Ji JH, Hwang IG, et al. Sedation for terminally ill cancer patients: A multicenter retrospective cohort study in South Korea. Medicine (Baltimore) 2019;98:e14278. https://doi.org/10.1097/MD.0000000000014278
  18. Won YW, Chun HS, Seo M, Kim RB, Kim JH, Kang JH. Clinical Patterns of Continuous and Intermittent Palliative Sedation in Patients With Terminal Cancer: A Descriptive, Observational Study. J Pain Symptom Manage 2019;58:65-71. https://doi.org/10.1016/j.jpainsymman.2019.04.019
  19. Lipuma SH. Continuous sedation until death as physician-assisted suicide/euthanasia: a conceptual analysis. J Med Philos 2013;38:190-204. https://doi.org/10.1093/jmp/jht005
  20. Anquinet L, Raus K, Sterckx S, Smets T, Deliens L, Rietjens JA. Similarities and differences between continuous sedation until death and euthanasia - professional caregivers’ attitudes and experiences: a focus group study. Palliat Med 2013;27:553-61. https://doi.org/10.1177/0269216312462272
  21. Sanjo M, Miyashita M, Morita T, Hirai K, Kawa M, Akechi T, et al. Preferences regarding end-of-life cancer care and associations with good-death concepts: a population-based survey in Japan. Ann Oncol 2007;18:1539-47. https://doi.org/10.1093/annonc/mdm199
  22. Morita T, Hirai K, Okazaki Y. Preferences for palliative sedation therapy in the Japanese general population. J Palliat Med 2002;5:375-85. https://doi.org/10.1089/109662102320135261