Korean journal of dermatology (대한피부과학회지)

Korean Dermatological Association (대한피부과학회)
권호 표지

A Case of Refractory Vitiligo Treated with Non-cultured Epidermal Cell Suspension Transplantation Using Suction Blister Method

흡입수포를 이용한 비배양표피세포이식술로 치료한 난치성 백반증 1예

  • Eun, Sung Hye (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jung, Yu Seok (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Lee, Hanna (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Lee, Ji Hae (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Kim, Gyong Moon (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Bae, Jung Min (Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea)
  • 은성혜 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실) ;
  • 정유석 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실) ;
  • 이한나 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실) ;
  • 이지혜 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실) ;
  • 김경문 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실) ;
  • 배정민 (가톨릭대학교 의과대학 성빈센트병원 피부과학교실)
  • Received : 2017.03.06
  • Accepted : 2017.10.24
  • Published : 2018.11.30
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Abstract

Vitiligo is a commonly acquired cutaneous depigmentation disorder that affects 0.5~1% of the population worldwide. While phototherapy is the primary treatment for vitiligo, surgical methods can be used for treating patients who are refractory to conventional treatments. Herein, we present the case of a 14-year-old Korean girl who developed vitiligo after hematopoietic stem cell transplantation for the treatment of acute lymphoblastic leukemia. She had multiple depigmented patches on her lower legs that did not respond to narrow-band ultraviolet B phototherapy for 7 months. The depigmented patches were successfully treated by transplantation of non-cultured epidermal cell suspension from the epidermal roof of the suction blister in the right inner thigh. No adverse event, such as secondary infection or scarring in both the donor and recipient sites, was noted. We recommended that non-cultured epidermal cell suspension transplantation using the suction blister method would be a safe and effective option for the treatment of refractory vitiligo.

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