Acknowledgement
Supported by : Jeju National University
References
- Wang D, Lippard SJ. Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 2005;4:307-20. https://doi.org/10.1038/nrd1691
- Pabla N, Dong Z. Cisplatin nephrotoxicity: mechanisms and renoprotective strategies. Kidney Int 2008;73:994-1007. https://doi.org/10.1038/sj.ki.5002786
- Arany I, Safirstein RL. Cisplatin nephrotoxicity. Semin Nephrol 2003;23:460-4. https://doi.org/10.1016/S0270-9295(03)00089-5
- Lieberthal W, Triaca V, Levine J. Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis. Am J Physiol 1996;270(4 Pt 2):F700-8.
- Park S, Yoon SP, Kim J. Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells. Anat Cell Biol 2015;48:66-74. https://doi.org/10.5115/acb.2015.48.1.66
- Pabla N, Murphy RF, Liu K, Dong Z. The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity. Am J Physiol Renal Physiol 2009;296: F505-11. https://doi.org/10.1152/ajprenal.90545.2008
- Zhang D, Pan J, Xiang X, Liu Y, Dong G, Livingston MJ, Chen JK, Yin XM, Dong Z. Protein kinase Cdelta suppresses autophagy to induce kidney cell apoptosis in cisplatin nephrotoxicity. J Am Soc Nephrol 2017;28:1131-44. https://doi.org/10.1681/ASN.2016030337
- Nozaki Y, Kinoshita K, Hino S, Yano T, Niki K, Hirooka Y, Kishimoto K, Funauchi M, Matsumura I. Signaling Rho-kinase mediates inflammation and apoptosis in T cells and renal tubules in cisplatin nephrotoxicity. Am J Physiol Renal Physiol 2015;308: F899-909. https://doi.org/10.1152/ajprenal.00362.2014
- Sridevi P, Nhiayi MK, Wang JY. Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatininduced nephrotoxicity. Cell Death Differ 2013;20:953-62. https://doi.org/10.1038/cdd.2013.42
- Yoon SP, Kim J. Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity. Anat Cell Biol 2016;49:165-76. https://doi.org/10.5115/acb.2016.49.3.165
- Kim J. Poly(ADP-ribose) polymerase activation induces high mobility group box 1 release from proximal tubular cells during cisplatin nephrotoxicity. Physiol Res 2016;65:333-40.
- Kim J, Long KE, Tang K, Padanilam BJ. Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity. Kidney Int 2012;82:193-203. https://doi.org/10.1038/ki.2012.64
- Tristao VR, Pessoa EA, Nakamichi R, Reis LA, Batista MC, Durao Junior Mde S, Monte JC. Synergistic effect of apoptosis and necroptosis inhibitors in cisplatin-induced nephrotoxicity. Apoptosis 2016;21:51-9. https://doi.org/10.1007/s10495-015-1190-5
- Pegg AE. Functions of polyamines in mammals. J Biol Chem 2016;291:14904-12. https://doi.org/10.1074/jbc.R116.731661
- Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Buttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Muhlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 2016;22:1428-38. https://doi.org/10.1038/nm.4222
- Eisenberg T, Knauer H, Schauer A, Buttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck- Loebenstein B, Herker E, Fahrenkrog B, Frohlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 2009; 11:1305-14. https://doi.org/10.1038/ncb1975
- Kim J. Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation. Anat Cell Biol 2017;50:200-6. https://doi.org/10.5115/acb.2017.50.3.200
- Kim J. Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury. Arch Pharm Res 2017;40:1197-208. https://doi.org/10.1007/s12272-017-0957-3
- Kim J, Devalaraja-Narashimha K, Padanilam BJ. TIGAR regulates glycolysis in ischemic kidney proximal tubules. Am J Physiol Renal Physiol 2015;308:F298-308. https://doi.org/10.1152/ajprenal.00459.2014
- Yoon SP, Kim J. Exogenous CGRP upregulates profibrogenic growth factors through PKC/JNK signaling pathway in kidney proximal tubular cells. Cell Biol Toxicol 2018;34:251-62. https://doi.org/10.1007/s10565-017-9399-4
- Magnes C, Fauland A, Gander E, Narath S, Ratzer M, Eisenberg T, Madeo F, Pieber T, Sinner F. Polyamines in biological samples: rapid and robust quantification by solid-phase extraction onlinecoupled to liquid chromatography-tandem mass spectrometry. J Chromatogr A 2014;1331:44-51. https://doi.org/10.1016/j.chroma.2013.12.061
- Yoon SP, Kim J. Poly(ADP-ribose) polymerase 1 activation links ischemic acute kidney injury to interstitial fibrosis. J Physiol Sci 2015;65:105-11. https://doi.org/10.1007/s12576-014-0346-3
- Kim J, Padanilam BJ. Renal denervation prevents long-term sequelae of ischemic renal injury. Kidney Int 2015;87:350-8. https://doi.org/10.1038/ki.2014.300
- Kim J, Padanilam BJ. Renal nerves drive interstitial fibrogenesis in obstructive nephropathy. J Am Soc Nephrol 2013;24:229-42. https://doi.org/10.1681/ASN.2012070678
- Kim J, Padanilam BJ. Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction. Am J Physiol Renal Physiol 2011;301:F450-9. https://doi.org/10.1152/ajprenal.00059.2011
- Song H, Yoon SP, Kim J. Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells. Anat Cell Biol 2016;49:79-87. https://doi.org/10.5115/acb.2016.49.2.79
- Lee JS, Lim JY, Kim J. Mechanical stretch induces angiotensinogen expression through PARP1 activation in kidney proximal tubular cells. In Vitro Cell Dev Biol Anim 2015;51:72-8. https://doi.org/10.1007/s11626-014-9809-3
- Chirino YI, Pedraza-Chaverri J. Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity. Exp Toxicol Pathol 2009;61:223-42. https://doi.org/10.1016/j.etp.2008.09.003
- Filipovic DM, Meng X, Reeves WB. Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells. Am J Physiol 1999;277(3 Pt 2):F428-36.
- Krishnakumar R, Kraus WL. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell 2010;39:8-24. https://doi.org/10.1016/j.molcel.2010.06.017
- Stachurska A, Dudkowska M, Czopek A, Manteuffel-Cymborowska M, Grzelakowska-Sztabert B. Cisplatin up-regulates the in vivo biosynthesis and degradation of renal polyamines and c-Myc expression. Biochim Biophys Acta 2004;1689:259-66. https://doi.org/10.1016/j.bbadis.2004.04.003
- Thompson KL, Afshari CA, Amin RP, Bertram TA, Car B, Cunningham M, Kind C, Kramer JA, Lawton M, Mirsky M, Naciff JM, Oreffo V, Pine PS, Sistare FD. Identification of platformindependent gene expression markers of cisplatin nephrotoxicity. Environ Health Perspect 2004;112:488-94. https://doi.org/10.1289/ehp.6676
- Xu Y, Ma H, Shao J, Wu J, Zhou L, Zhang Z, Wang Y, Huang Z, Ren J, Liu S, Chen X, Han J. A role for tubular necroptosis in cisplatin-induced AKI. J Am Soc Nephrol 2015;26:2647-58. https://doi.org/10.1681/ASN.2014080741
- Jamieson ER, Lippard SJ. Structure, recognition, and processing of cisplatin-DNA adducts. Chem Rev 1999;99:2467-98. https://doi.org/10.1021/cr980421n
- Ahmed LA, Shehata NI, Abdelkader NF, Khattab MM. Tempol, a superoxide dismutase mimetic agent, ameliorates cisplatininduced nephrotoxicity through alleviation of mitochondrial dysfunction in mice. PLoS One 2014;9:e108889. https://doi.org/10.1371/journal.pone.0108889
- Davis CA, Nick HS, Agarwal A. Manganese superoxide dismutase attenuates cisplatin-induced renal injury: importance of superoxide. J Am Soc Nephrol 2001;12:2683-90.
- Mansour MA, Mostafa AM, Nagi MN, Khattab MM, Al-Shabanah OA. Protective effect of aminoguanidine against nephrotoxicity induced by cisplatin in normal rats. Comp Biochem Physiol C Toxicol Pharmacol 2002;132:123-8. https://doi.org/10.1016/S1532-0456(02)00062-5
- Mansour MA, Al-Shabanah OA, El-Khashef HA. L-arginine ameliorates kidney function and urinary bladder sensitivity in experimentally-induced renal dysfunction in rats. J Biochem Mol Biol 2003;36:373-8.
- Chirino YI, Hernandez-Pando R, Pedraza-Chaverri J. Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats. BMC Pharmacol 2004;4:20. https://doi.org/10.1186/1471-2210-4-20
- Ayala A, Munoz MF, Arguelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev 2014;2014:360438.
- Marnett LJ. Oxy radicals, lipid peroxidation and DNA damage. Toxicology 2002;181-182:219-22. https://doi.org/10.1016/S0300-483X(02)00448-1
- Masuda H, Tanaka T, Takahama U. Cisplatin generates superoxide anion by interaction with DNA in a cell-free system. Biochem Biophys Res Commun 1994;203:1175-80. https://doi.org/10.1006/bbrc.1994.2306
- Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418:191-5. https://doi.org/10.1038/nature00858
- Obrosova IG, Drel VR, Pacher P, Ilnytska O, Wang ZQ, Stevens MJ, Yorek MA. Oxidative-nitrosative stress and poly(ADPribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited. Diabetes 2005;54:3435-41. https://doi.org/10.2337/diabetes.54.12.3435
- Ungvari Z, Gupte SA, Recchia FA, Batkai S, Pacher P. Role of oxidative-nitrosative stress and downstream pathways in various forms of cardiomyopathy and heart failure. Curr Vasc Pharmacol 2005;3:221-9. https://doi.org/10.2174/1570161054368607
- Ha HC, Snyder SH. Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci U S A 1999;96:13978-82. https://doi.org/10.1073/pnas.96.24.13978
- Bouchard VJ, Rouleau M, Poirier GG. PARP-1, a determinant of cell survival in response to DNA damage. Exp Hematol 2003;31: 446-54. https://doi.org/10.1016/S0301-472X(03)00083-3
- Marton LJ, Pegg AE. Polyamines as targets for therapeutic intervention. Annu Rev Pharmacol Toxicol 1995;35:55-91. https://doi.org/10.1146/annurev.pa.35.040195.000415
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