Journal of Animal Science and Technology

Korean Society of Animal Sciences and Technology (한국축산학회)
권호 표지
DOI QR코드

DOI QR Code

Protective effect of soursop (Annona muricata linn.) juice on oxidative stress in heat stressed rabbits

  • Received : 2018.09.25
  • Accepted : 2018.11.02
  • Published : 2018.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Preventing oxidative stress in heat stressed animals may be possible by increasing antioxidant defence via exogenous administration of antioxidant substrate and/or its precursors. The study aimed to investigate the effect of Soursop juice in mitigating oxidative stress induced by heat stress in rabbit. Methods: Sixty mixed breed rabbit bucks aged 12-18 months old with the average weight of $1826{\pm}8.35$ g/rabbit, randomly allotted to experimental treatments of four replicates each, in a completely randomized design during high-temperature humidity index in Ado Ekiti, Southwest Nigeria. Soursop juice (SSJ) was administered via oral drenched daily per kg body weight (BW), to designated treatment 1 to 5; $0.55mlkg^{-1}BW$ distilled water (control), $0.55mlkg^{-1}BW$ SSJ, $1.11mlkg^{-1}BW$ SSJ, $1.67mlkg^{-1}BW$ SSJ and $2.22mlkg^{-1}BW$ SSJ, respectively. Fastened blood samples were collected at days 28 and 56, and assay for serum protein, cholesterol, triglycerides, superoxide dismutase, catalase, reduced glutathione and lipid peroxidation using standard procedures. Result: Result revealed that SSJ demonstrated hypocholesterolemic effect in a dose-dependent manner throughout the study. Effect of chronic administration of SSJ to heat stressed rabbits proved beneficial, as SSJ reduced serum lipid peroxidation and enhanced antioxidant activity over 8 weeks. Conclusion: Administration of soursop juice to heat-stressed bucks at $2.22mlkg^{-1}BW$ offered optimum antioxidant defense against oxidative stress.

Keywords

References

  1. Jimoh OA, Ewuola EO. Thermoregulatory response of exotic rabbit breeds during peak temperature humidity index of Ibadan. Tropical Animal Production investigation. 2016;19(1):41-7.
  2. Jimoh OA, Ewuola EO, Balogun AS. Oxidative stress markers in exotic breeds of rabbit during peak of heat stress in Ibadan, Nigeria. Journal of Advances in Biology and Biotechnology. 2017;12(1):1-9. https://doi.org/10.9734/JABB/2017/30437.
  3. Jimoh OA. Assessment of the oxidative stress markers and reproductive performance of four exotic breeds of rabbit in Ibadan. Ph.D. Thesis 2016, University of Ibadan, Ibadan, Nigeria.
  4. Adewole SO,Ojewole JAO. Protective effects of Annona muricata linn. (annonaceae) leaf aqueous extract on serum lipid profiles and oxidative stress in hepatocytes of streptozotocin-treated diabetic rats. Afr. J. Traditional, Complementary and Alternative Medicines 2009, 6 (1): 30-41.
  5. Marai IFM, Ayyat MS. Abd El-MonemUM. Growth performance and reproductive traits at first parity of New Zealand white female rabbits as affected by heat stress and its alleviation, under Egyptian conditions. Trop Anim Health Prod. 2001;33:1-12. https://doi.org/10.1023/A:1010369024658
  6. Sawant TP, Gogle DP. A brief review on recent advances in clinical research of Annona muricata. International journal of universal pharmacy and bio. Sciences. 2014;3(3):267-304.
  7. Zheng J, Zhou Y, Li S, Zhang P, Zhou T, D X, Li H. Review effects and mechanisms of fruit and vegetable juices on cardiovascular diseases. Int J Mol Sci. 2017;18(555):1-15. https://doi.org/10.3390/ijms18030555.
  8. Han CH, Kim SH, Kang SH, Shin OR, Lee HK, Kim HJ, Cho YH. Protective effects of cranberries on infected-induced oxidative renal damage in a rabbit model of vesico-ureteric reflux. BJU Int. 2007;100:1172-5.
  9. Ahmed RS, Seth V, Pasha ST, Banerjee BD. Influence of dietary ginger (Zingiber Officinale Rosc) on oxidative stress induced by malathion in rats. Food Chem Toxicol. 2000;38:443-50. https://doi.org/10.1016/S0278-6915(00)00019-3
  10. Kota N, Krishna P, Polasa K. Alterations in antioxidant status of rats following intake of ginger through diet. Food Chem. 2008;106:991-6. https://doi.org/10.1016/j.foodchem.2007.07.073
  11. Smarsh DN, Liburt N, Streltsova J, Mckeever K, Williams CA. Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts. Equine Vet J. 2010;42(Suppl. 38):317-22. https://doi.org/10.1111/j.2042-3306.2010.00182.x.
  12. Syahida M, Maskat MY, Suri R, Mamot S, Hadijah H. Soursop (Annona muricata L.): blood hematology and serum biochemistry of Sprague-Dawley rats. Int Food Res J. 2012;19(3):955-9.

Cited by

  1. Processed cocoa pod husk dietary inclusion: effects on the performance, carcass, haematogram, biochemical indices, antioxidant enzyme and histology of the liver and kidney in broiler chicken vol.43, pp.1, 2019, https://doi.org/10.1186/s42269-019-0096-8
  2. Liver Transcriptome Changes of Hyla Rabbit in Response to Chronic Heat Stress vol.9, pp.12, 2018, https://doi.org/10.3390/ani9121141
  3. Annona Genus: Traditional Uses, Phytochemistry and Biological Activities vol.26, pp.33, 2018, https://doi.org/10.2174/1381612826666200325094422
  4. Potential of watermelon (Citrullus lanatus) to maintain oxidative stability of rooster semen for artificial insemination vol.63, pp.1, 2018, https://doi.org/10.5187/jast.2021.e21
  5. Heat stress on microbiota composition, barrier integrity, and nutrient transport in gut, production performance, and its amelioration in farm animals vol.63, pp.2, 2018, https://doi.org/10.5187/jast.2021.e48
  6. Interaction of supplementary L-carnitine and dietary energy levels on feed utilization and blood constituents in New Zealand White rabbits reared under summer conditions vol.53, pp.2, 2018, https://doi.org/10.1007/s11250-021-02723-1
  7. The elemental status of broiler chickens when used the cocoa husks in the diet vol.848, pp.1, 2021, https://doi.org/10.1088/1755-1315/848/1/012055
  8. Effect of biologically upgraded cocoa pod husk meal on growth, serum and antioxidant properties of two rabbit breeds vol.45, pp.1, 2018, https://doi.org/10.1186/s42269-020-00454-1