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정서경험과 생체노화

The Effect of Emotional Experiences on Biological Aging

  • 백서채 (충남대학교병원 가정의학과) ;
  • 김종성 (충남대학교병원 가정의학과)
  • Paik, Seo Chae (Department of Family Medicine, Chungnam National University Hospital) ;
  • Kim, Jong Sung (Department of Family Medicine, Chungnam National University Hospital)
  • 투고 : 2018.08.29
  • 심사 : 2018.12.21
  • 발행 : 2018.12.30

초록

연구배경: 본 연구는 인간이 평소에 부정적인 정서들을 경험하는 것과 생물학적 노화 사이의 연관성을 알아보기 위하여 고안되었다. 방법: 2013년 5월부터 9월까지 충남대학교병원 건강증진센터를 내원한 237명을 대상으로 연구하였다. 피험자들 개개인에게 구조화된 설문지를 주어 응답하도록 하였다. 피험자들이 '평소에 느끼는 우울, 불안, 분노 그리고 분노표현' (이하 '정서경험들')은 특성우울척도([the Korean adaptation of] State-Trait Depression Inventory에서 분리함), 특성불안척도(한국형 상태-특성불안척도[State-Trait Anxiety Inventory]에서 분리함) 그리고 특성분노척도와 분노표현척도([the Korean adaptation of] State-Trait Anger Expression Inventory에서 분리함)로 사정하였다. 피험자들 각각이 '생물학적으로 노화가 진행되는 정도' (이하 '생체노화')는 생체 연령(비만과 주요 장기들의 노화를 반영)과 실제 나이로 이루어진 특수한 공식으로 계산하였다. 독립 t-검정, 일원분산분석, 상관분석을 시행하여 피험자들의 일반적 특성들(정서경험들을 포함)과 생체노화들 간의 연관성들을 평가하였다. 단계적 회귀분석을 사용하여 피험자들의 일반적 특성들과 생체노화들 간의 설명력($R^2$)들을 산출하였다. 결과: 일변량분석에서 오직 특성분노와 교육수준만이 생체노화와 유의한 상관관계를 보였다; 전자의 경우는 r=0.160, P=0.014, 후자는 r=-0.189, P=0.024. 다변량분석에서는 특성 분노와 낮은 교육수준만이 생체노화와 유의한 설명력을 나타냈다; 전자의 경우는 $R^2=0.044$, P=0.020, 후자는 $R^2=0.022$, P=0.038. 결론: 본 연구는 평소에 경험하는 분노(즉 특성분노)와 낮은 교육수준이 인체의 생물학적 노화를 촉진시키는 주목할 만한 요인들임을 시사한다.

Background: This study was designed to investigate the effects of usual negative emotional experiences on biological aging progression of human. Methods: A total of 237 subjects who visited the Health Promotion Center at Chungnam National University Hospital from May 2013 through September 2013 was enrolled. Each subject had been drawn up a structured questionnaire about usual experiences of depression, anxiety, anger, and anger expression. The degree of biological aging progression of each subject was computed by a specific formula which consisted of chronological age and biological age reflecting obesity and aging of main organs. Results: Trait anger and low education level showed the significant correlations with biological aging (r=0.160, P=0.014, and r=-0.189, P=0.024, respectively). Trait anger and low education level solely displayed the significant $R^2s$ for biological aging in consequence of multivariate analyses; $R^2=0.044$, P=0.020, and $R^2=0.022$, P=0.038, respectively. Conclusions: This study suggests that the significant relationship between usual anger experience (i.e., trait anger) and biological aging would be present. In addition, lower education level may be related with biological aging.

키워드

참고문헌

  1. Cannon WB. The wisdom of the body. New York: W.W. Norton & Company, Inc.; 1932. p.218-42.
  2. Romero ML, Butler LK. Endocrinology of stress. Int J Comp Psychol 2007;20(2):89-95.
  3. al'Absi M, Bongard S. Neuroendocrine and behavioral mechanisms mediating the relationship between anger expression and cardiovascular risk: assessment considerations and improvements. J Behav Med 2006;29(6):573-91. https://doi.org/10.1007/s10865-006-9077-0
  4. Cohen BE, Panguluri P, Na B, Whooley MA. Psychological risk factors and the metabolic syndrome in patients with coronary heart disease: findings from the heart and soul study. Psychiatry Res 2010;175(1-2):133-7. https://doi.org/10.1016/j.psychres.2009.02.004
  5. Schrag A, Jahanshahi M, Quinn N. What contributes to quality of life in patients with Parkinson's disease? J Neurol Neurosurg Psychiatry 2000;69(3):308-12. https://doi.org/10.1136/jnnp.69.3.308
  6. Kathol RG, Mutgi A, Williams J, Clamon G, Noyes R Jr. Diagnosis of major depression in cancer patients according to four sets of criteria. Am J Psychiatry 1990;147(8):1021-4. https://doi.org/10.1176/ajp.147.8.1021
  7. Raikkonen K, Matthews KA, Kuller LH. The relationship between psychological risk attributes and the metabolic syndrome in healthy women: antecedent or consequence? Metabolism 2002;51(12):1573-7. https://doi.org/10.1053/meta.2002.36301
  8. Chignon JM, Lepine JP, Ades J. Panic disorder in cardiac outpatients. Am J Psychiatry 1993;150(5):780-5. https://doi.org/10.1176/ajp.150.5.780
  9. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961;4(6):561-71. https://doi.org/10.1001/archpsyc.1961.01710120031004
  10. Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 1988;56(6):893-7. https://doi.org/10.1037/0022-006X.56.6.893
  11. Zung WW. A self-rating depression scale. Arch Gen Psychiatry 1965;12(1):63-70. https://doi.org/10.1001/archpsyc.1965.01720310065008
  12. Zung WW. A rating instrument for anxiety disorders. Psychosomatics 1971;12(6):371-9. https://doi.org/10.1016/S0033-3182(71)71479-0
  13. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23(1):56-62. https://doi.org/10.1136/jnnp.23.1.56
  14. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959;32(1):50-5. https://doi.org/10.1111/j.2044-8341.1959.tb00467.x
  15. Spielberger CD, Reheiser EC. Assessment of emotions: anxiety, anger, depression, and curiosity. Appl Psychol Health Well Being 2009;1(3):271-302. https://doi.org/10.1111/j.1758-0854.2009.01017.x
  16. Lee CH, Chon KK, Hahn DW, Kim KH. The Korean adaptation of the State-Trait Depression Inventory: STDI-K. Korean J Health Psychol 1999;4(1):1-14.
  17. Spielberger CD, Gorsuch RL, Lushene RE. Manual for the state-trait anxiety inventory. Palo Alto: Consulting Psychologist Press; 1970. p.1-2.
  18. Kim JT. The relationship of the trait anxiety and sociality [dissertation]. Seoul: Korea University; 1978. Korean.
  19. Lee YJ, Bhang SY, Choi S, Lee HK, Kim BW, Kim W, et al. Korean state-trait anxiety inventory application study in middle and high school students. J Korean Neuropsychiatr Assoc 2008;47(5):471-80.
  20. Spielberger CD, Sydeman SJ. State-trait anxiety inventory and state-trait anger expression inventory. In: Maruish ME, ed. The use of psychological testing for treatment planning and outcome assessment: 1st edition. Hillsdale: Lawrence Erlbaum Associates; 1994. p.292-321.
  21. Hahn DW, Lee CH, Chon KK. Korean adaptation of the State-Trait Anger Expression Inventory (STAXI-K): the case of college students. Korean J Health Psychol 1998;3(1):18-32.
  22. Bae CY, Kang YG, Kim S, Cho C, Kang HC, Yu BY, et al. Development of models for predicting biological age (BA) with physical, biochemical, and hormonal parameters. Arch Gerontol Geriatr 2008:47(2):253-65. https://doi.org/10.1016/j.archger.2007.08.009
  23. Park JH, Cho BL, Kwon HT, Lee CM. Developing a biological age assessment equation using principal component analysis and clinical biomarkers of aging in Korean men. Arch Gerontol Geriatr 2009;49(1):7-12. https://doi.org/10.1016/j.archger.2008.04.003
  24. Hahn DW, Park JH, Kim KH. Effects of self-disclosure and rumination about stressful life event and emotional experiences on physical health. Korean J Health Psychol 2004;9(1):99-130. https://doi.org/10.1177/1359105304036104
  25. Menendez JA, Joven J. Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer. Adv Exp Med Biol 2014;824:117-40.
  26. Arun CP. Fight or flight, forbearance and fortitude: the spectrum of actions of the catecholamines and their cousins. Ann N Y Acad Sci 2004;1018:137-40. https://doi.org/10.1196/annals.1296.016
  27. Baltrusch HJ, Stangel W, Titze I. Stress, cancer and immunity. New developments in biopsychosocial and psychoneuroimmunologic research. Acta Neurol (Napoli) 1991;13(4):315-27.
  28. Dannehl K, Rief W, Schwarz MJ, Hennings A, Riemer S, Selberdinger V, et al. The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression. Neuropsychiatr Dis Treat 2014;28(10):1191-7.
  29. Logan JG, Barksdale DJ, Carlson J, Carlson BW, Rowsey PJ. Psychological stress and arterial stiffness in Korean Americans. J Psychosom Res 2012;73(1):53-8. https://doi.org/10.1016/j.jpsychores.2012.04.008
  30. Jankovic S, Stojisavljevic D, Jankovic J, Eric M, Marinkovic J. Association of socioeconomic status measured by education, and cardiovascular health: a population-based cross-sectional study. BMJ Open 2014;4(7):e005222. https://doi.org/10.1136/bmjopen-2014-005222