DOI QR코드

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Current landscape and future perspective of sentinel node mapping in endometrial cancer

  • 투고 : 2018.07.04
  • 심사 : 2018.08.01
  • 발행 : 2018.11.10

초록

Endometrial cancer (EC) represents the most common gynecological neoplasm in developed countries. Surgery is the mainstay of treatment for EC. Although EC is characterized by a high prevalence several features regarding its management are still unclear. In particular the execution of lymphadenectomy is controversial. The recent introduction of sentinel node mapping represents the mid-way between the execution and omission of node dissection in EC patients. In the present review we discuss the emerging role of sentinel node mapping in EC. In addition, we discussed how type of tracers utilized and site of injection impacted on sentinel node detection rates. Future perspective regarding EC management are also discussed.

키워드

참고문헌

  1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007. CA Cancer J Clin 2007;57:43-66. https://doi.org/10.3322/canjclin.57.1.43
  2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017. CA Cancer J Clin 2017;67:7-30. https://doi.org/10.3322/caac.21387
  3. Bogani G, Dowdy SC, Cliby WA, Ghezzi F, Rossetti D, Frigerio L, et al. Management of endometrial cancer: issues and controversies. Eur J Gynaecol Oncol 2016;37:6-12.
  4. Bogani G, Dowdy SC, Cliby WA, Ghezzi F, Rossetti D, Mariani A. Role of pelvic and para-aortic lymphadenectomy in endometrial cancer: current evidence. J Obstet Gynaecol Res 2014;40:301-11. https://doi.org/10.1111/jog.12344
  5. Bogani G, Multinu F, Dowdy SC, Cliby WA, Wilson TO, Gostout BS, et al. Incorporating robotic-assisted surgery for endometrial cancer staging: analysis of morbidity and costs. Gynecol Oncol 2016;141:218-24. https://doi.org/10.1016/j.ygyno.2016.02.016
  6. Colombo N, Creutzberg C, Amant F, Bosse T, Gonzalez-Martin A, Ledermann J, et al. ESMO-ESGO-ESTRO Consensus Conference on endometrial cancer: diagnosis, treatment and follow-up. Int J Gynecol Cancer 2016;26:2-30. https://doi.org/10.1097/IGC.0000000000000609
  7. Mariani A, Dowdy SC, Cliby WA, Gostout BS, Jones MB, Wilson TO, et al. Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging. Gynecol Oncol 2008;109:11-8. https://doi.org/10.1016/j.ygyno.2008.01.023
  8. Fotopoulou C, Savvatis K, Kraetschell R, Schefold JC, Lichtenegger W, Sehouli J. Systematic pelvic and aortic lymphadenectomy in intermediate and high-risk endometrial cancer: lymph-node mapping and identification of predictive factors for lymph-node status. Eur J Obstet Gynecol Reprod Biol 2010;149:199-203. https://doi.org/10.1016/j.ejogrb.2009.12.021
  9. Benedetti Panici P, Basile S, Maneschi F, Alberto Lissoni A, Signorelli M, Scambia G, et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst 2008;100:1707-16. https://doi.org/10.1093/jnci/djn397
  10. ASTEC study groupKitchener H, Swart AM, Qian Q, Amos C, Parmar MK. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet 2009;373:125-36. https://doi.org/10.1016/S0140-6736(08)61766-3
  11. Frost JA, Webster KE, Bryant A, Morrison J. Lymphadenectomy for the management of endometrial cancer. Cochrane Database Syst Rev 2017:CD007585.
  12. Todo Y, Kato H, Kaneuchi M, Watari H, Takeda M, Sakuragi N. Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis. Lancet 2010;375:1165-72. https://doi.org/10.1016/S0140-6736(09)62002-X
  13. Burke TW, Levenback C, Tornos C, Morris M, Wharton JT, Gershenson DM. Intraabdominal lymphatic mapping to direct selective pelvic and paraaortic lymphadenectomy in women with high-risk endometrial cancer: results of a pilot study. Gynecol Oncol 1996;62:169-73. https://doi.org/10.1006/gyno.1996.0211
  14. National Center for Biotechnology Information. PubMed database [Internet]. Bethesda, MD: National Center for Biotechnology Information; [cited 2018 May 18]. Available from: https://www.ncbi.nlm.nih.gov/pubmed/?term=sentinel+node+and+endometral+cancer.
  15. Barlin JN, Khoury-Collado F, Kim CH, Leitao MM Jr, Chi DS, Sonoda Y, et al. The importance of applying a sentinel lymph node mapping algorithm in endometrial cancer staging: beyond removal of blue nodes. Gynecol Oncol 2012;125:531-5. https://doi.org/10.1016/j.ygyno.2012.02.021
  16. Cibula D, Oonk MH, Abu-Rustum NR. Sentinel lymph node biopsy in the management of gynecologic cancer. Curr Opin Obstet Gynecol 2015;27:66-72. https://doi.org/10.1097/GCO.0000000000000133
  17. Darai E, Dubernard G, Bats AS, Heitz D, Mathevet P, Marret H, et al. Sentinel node biopsy for the management of early stage endometrial cancer: long-term results of the SENTI-ENDO study. Gynecol Oncol 2015;136:54-9. https://doi.org/10.1016/j.ygyno.2014.09.011
  18. Soliman PT, Westin SN, Dioun S, Sun CC, Euscher E, Munsell MF, et al. A prospective validation study of sentinel lymph node mapping for high-risk endometrial cancer. Gynecol Oncol 2017;146:234-9. https://doi.org/10.1016/j.ygyno.2017.05.016
  19. Koh WJ, Abu-Rustum NR, Bean S, Bradley K, Campos SM, Cho KR, et al. Uterine neoplasms, version 1.2018, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 2018;16:170-99. https://doi.org/10.6004/jnccn.2018.0006
  20. Elisei F, Crivellaro C, Giuliani D, Dolci C, De Ponti E, Montanelli L, et al. Sentinel-node mapping in endometrial cancer patients: comparing SPECT/CT, gamma-probe and dye. Ann Nucl Med 2017;31:93-9. https://doi.org/10.1007/s12149-016-1137-0
  21. Papadia A, Gasparri ML, Buda A, Mueller MD. Sentinel lymph node mapping in endometrial cancer: comparison of fluorescence dye with traditional radiocolloid and blue. J Cancer Res Clin Oncol 2017;143:2039-48. https://doi.org/10.1007/s00432-017-2501-8
  22. Tanner EJ, Sinno AK, Stone RL, Levinson KL, Long KC, Fader AN. Factors associated with successful bilateral sentinel lymph node mapping in endometrial cancer. Gynecol Oncol 2015;138:542-7. https://doi.org/10.1016/j.ygyno.2015.06.024
  23. Eriksson AG, Montovano M, Beavis A, Soslow RA, Zhou Q, Abu-Rustum NR, et al. Impact of obesity on sentinel lymph node mapping in patients with newly diagnosed uterine cancer undergoing robotic surgery. Ann Surg Oncol 2016;23:2522-8. https://doi.org/10.1245/s10434-016-5134-2
  24. Montgomery LL, Thorne AC, Van Zee KJ, Fey J, Heerdt AS, Gemignani M, et al. Isosulfan blue dye reactions during sentinel lymph node mapping for breast cancer. Anesth Analg 2002.95:385-8.
  25. Cormier B, Rozenholc AT, Gotlieb W, Plante M, Giede CCommunities of Practice (CoP) Group of Society of Gynecologic Oncology of Canada (GOC). Sentinel lymph node procedure in endometrial cancer: a systematic review and proposal for standardization of future research. Gynecol Oncol 2015;138:478-85. https://doi.org/10.1016/j.ygyno.2015.05.039
  26. Bogani G, Martinelli F, Ditto A, Signorelli M, Chiappa V, Recalcati D, et al. Sentinel lymph node detection in endometrial cancer: does injection site make a difference? J Gynecol Oncol 2016;27:e23. https://doi.org/10.3802/jgo.2016.27.e23
  27. Leitao MM Jr, Khoury-Collado F, Gardner G, Sonoda Y, Brown CL, Alektiar KM, et al. Impact of incorporating an algorithm that utilizes sentinel lymph node mapping during minimally invasive procedures on the detection of stage IIIC endometrial cancer. Gynecol Oncol 2013;129:38-41. https://doi.org/10.1016/j.ygyno.2013.01.002
  28. Rossi EC, Kowalski LD, Scalici J, Cantrell L, Schuler K, Hanna RK, et al. A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study. Lancet Oncol 2017;18:384-92. https://doi.org/10.1016/S1470-2045(17)30068-2
  29. Leitao MM Jr. Sentinel lymph node mapping in patients with endometrial carcinoma: less can be more. Curr Obstet Gynecol Rep 2016;5:279-85. https://doi.org/10.1007/s13669-016-0178-7
  30. Bogani G, Ditto A, Leone Roberti Maggiore U, Lorusso D, Raspagliesi F. Sentinel-lymph-node mapping in endometrial cancer. Lancet Oncol 2017;18:e234. https://doi.org/10.1016/S1470-2045(17)30247-4
  31. Geppert B, Lonnerfors C, Bollino M, Persson J. Sentinel lymph node biopsy in endometrial cancer-feasibility, safety and lymphatic complications. Gynecol Oncol 2018;148:491-8. https://doi.org/10.1016/j.ygyno.2017.12.017
  32. Zahl Eriksson AG, Ducie J, Ali N, McGree ME, Weaver AL, Bogani G, et al. Comparison of a sentinel lymph node and a selective lymphadenectomy algorithm in patients with endometrioid endometrial carcinoma and limited myometrial invasion. Gynecol Oncol 2016;140:394-9. https://doi.org/10.1016/j.ygyno.2015.12.028
  33. Ducie JA, Eriksson AG, Ali N, McGree ME, Weaver AL, Bogani G, et al. Comparison of a sentinel lymph node mapping algorithm and comprehensive lymphadenectomy in the detection of stage IIIC endometrial carcinoma at higher risk for nodal disease. Gynecol Oncol 2017;147:541-8. https://doi.org/10.1016/j.ygyno.2017.09.030
  34. Buda A, Di Martino G, Restaino S, De Ponti E, Monterossi G, Giuliani D, et al. The impact on survival of two different staging strategies in apparent early stage endometrial cancer comparing sentinel lymph nodes mapping algorithm and selective lymphadenectomy: an Italian retrospective analysis of two reference centers. Gynecol Oncol 2017;147:528-34. https://doi.org/10.1016/j.ygyno.2017.09.033
  35. Kataoka F, Susumu N, Yamagami W, Kuwahata M, Takigawa A, Nomura H, et al. The importance of para-aortic lymph nodes in sentinel lymph node mapping for endometrial cancer by using hysteroscopic radio-isotope tracer injection combined with subserosal dye injection: Prospective study. Gynecol Oncol 2016;140:400-4. https://doi.org/10.1016/j.ygyno.2015.12.023
  36. Ruscito I, Gasparri ML, Braicu EI, Bellati F, Raio L, Sehouli J, et al. Sentinel node mapping in cervical and endometrial cancer: indocyanine green versus other conventional dyes-a meta-analysis. Ann Surg Oncol 2016;23:3749-56. https://doi.org/10.1245/s10434-016-5236-x
  37. Holloway RW, Abu-Rustum NR, Backes FJ, Boggess JF, Gotlieb WH, Jeffrey Lowery W, et al. Sentinel lymph node mapping and staging in endometrial cancer: a Society of Gynecologic Oncology literature review with consensus recommendations. Gynecol Oncol 2017;146:405-15. https://doi.org/10.1016/j.ygyno.2017.05.027
  38. St. Clair CM, Eriksson AG, Ducie JA, Jewell EL, Alektiar KM, Hensley ML, et al. Low-volume lymph node metastasis discovered during sentinel lymph node mapping for endometrial carcinoma. Ann Surg Oncol 2016;23:1653-9. https://doi.org/10.1245/s10434-015-5040-z
  39. Plante M, Stanleigh J, Renaud MC, Sebastianelli A, Grondin K, Gregoire J. Isolated tumor cells identified by sentinel lymph node mapping in endometrial cancer: Does adjuvant treatment matter? Gynecol Oncol 2017;146:240-6. https://doi.org/10.1016/j.ygyno.2017.05.024
  40. Ballester M, Naoura I, Chereau E, Seror J, Bats AS, Bricou A, et al. Sentinel node biopsy upstages patients with presumed low- and intermediate-risk endometrial cancer: results of a multicenter study. Ann Surg Oncol 2013;20:407-12. https://doi.org/10.1245/s10434-012-2683-x

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  1. Sentinel-Node Mapping by Intraoperative Near-Infrared Fluorescence in the Robotic Surgical Treatment of Endometrial Cancer vol.35, pp.4, 2018, https://doi.org/10.1089/gyn.2018.0106
  2. The role of sentinel node in early ovarian cancer: a systematic review vol.110, pp.4, 2018, https://doi.org/10.23736/s0026-4806.19.06145-7
  3. Biopsia selectiva de ganglio centinela en pacientes con cáncer de endometrio. Inicio de la técnica en el Hospital Universitario Virgen Macarena vol.48, pp.3, 2021, https://doi.org/10.1016/j.gine.2020.11.008
  4. Sentinel Node Mapping in Endometrial Cancer vol.34, pp.6, 2021, https://doi.org/10.1080/08941939.2019.1680778