Journal of Neurocritical Care (대한신경집중치료학회지)

The Korean Neurocritical Care Society (대한신경집중치료학회)
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A Variant Guillain-Barré Syndrome with Anti-Ganglioside Complex Antibody

  • Huh, So-Young (Department of Neurology, Kosin University College of Medicine) ;
  • Lee, So-Young (Department of Neurology, Kosin University College of Medicine) ;
  • Lee, Jin-Hyung (Department of Neurology, Kosin University College of Medicine) ;
  • Lee, Won Gu (Department of Neurology, Kosin University College of Medicine) ;
  • Kim, Jong Kuk (Department of Neurology, Dong-A University College of Medicine) ;
  • Yoon, Byeol-A (Department of Neurology, Dong-A University College of Medicine) ;
  • Kim, Nam Jun (Peripheral Neuropathy Research Center, Dong-A University College of Medicine)
  • Received : 2018.11.30
  • Accepted : 2018.12.17
  • Published : 2018.12.30
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Abstract

Background: Recently, anti-ganglioside complex (GSC) antibodies were discovered among the various subtypes of Guillain-$Barr{\acute{e}}$ syndrome. GSC is the novel glycoepitopes formed by two individual ganglioside molecules. Case Report: We present a 36-year-old man with overlap Miller Fisher syndrome and acute bulbar palsy who had anti-GSC antibody that provided diagnostic robustness. Conclusion: Anti-GSC testing could be considered important in patients who show atypical manifestation with negative antibody reaction against each constituent ganglioside.

Keywords

Acknowledgement

Supported by : national Research Foundation of Korea (NRF)

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