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Case Analysis of the Effects of Nucleoplasty and Chemonucleolysis on the Intervertebral Disc

척추의 추간판에 대한 수핵성형술과 화학적수핵융해술의 영향 증례분석

  • Hong, Youngki (Department of Sports, Health and Rehabilitation, Cheongju University)
  • 홍영기 (청주대학교 스포츠건강재활 전공)
  • Received : 2018.11.26
  • Accepted : 2018.12.26
  • Published : 2018.12.31

Abstract

Purpose: This study was evaluated the effects of nucleoplasty and chemonucleolysis, as interventional treatments for herniated intervertebral disc disease, on spinal tissues. Methods: Nucleoplasty using plasma beam and chemonucleolysis with collagenase were conducted on the spinal motion segments that were dissected from of human cadaver spine under fluoroscopic guidance. After the procedure, the intervertebral discs were transected, and the changes in gross findings were examined. Subsequently, the influence of the procedure on the nucleus pulposus, annuls fibrosus, and endplate was analyzed through a pathologic examination. Results: Nucleoplasty was confirmed to eliminate the local range of tissues in nucleus pulposus according to the procedure tract and to not affect other tissues. In chemonucleolysis, we found that collagenase diffused from the surgical site within the nucleus pulposus and was not present in the annulus fibrosus and endplate. Conclusions: The clinically-used interventional treatments that were investigated here were not found to do not cause additional damage to areas other than those targeted.

Keywords

Acknowledgement

Supported by : 청주대학교

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