Journal of Clinical Nutrition

The Korean Society for Parenteral and Enteral Nutrition (한국정맥경장영양학회)
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Parenteral Nutrition in Hospitalized Adult Patients in South Korea

성인 입원환자의 정맥영양요법 사용 현황

  • Ock, Miyoung (College of Pharmacy, Sookmyung Women's University) ;
  • Lee, Sera (College of Pharmacy, Sookmyung Women's University) ;
  • Kim, Hyunah (College of Pharmacy, Sookmyung Women's University)
  • 옥미영 (숙명여자대학교 약학대학) ;
  • 이세라 (숙명여자대학교 약학대학) ;
  • 김현아 (숙명여자대학교 약학대학)
  • Received : 2018.09.16
  • Accepted : 2018.11.27
  • Published : 2018.12.31
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Abstract

Purpose: Parenteral nutrition (PN) is known to provide therapeutic beneficial improvements in malnourished patients for whom enteral nutrition is not feasible. The objective of this study was to investigate the current clinical characteristics and utilization of PN in Korea. Methods: We analyzed the Health Insurance Review Agency National Inpatients Sample database from 2014 to 2016, which included 13% of all hospitalized patients in Korea. Adult patients aged 20 years or older and receiving premixed multi-chamber bag containing PN were included for this study. Patient characteristics, admission type, primary diagnosis, and hospital demographics were evaluated. SAS version 9.4 was used for data analysis. Results: From 2014 to 2016, 149,504 patients received premixed PN, with 226,281 PN prescriptions being written. The mean patient age was 65.0 years, and 81,876 patients (54.8%) were male. Premixed 3-chamber bag and 2-chamber bag PN solutions were utilized in 131,808 (88.2%) and 32,033 (21.4%) patients, respectively. The number of patients hospitalized through the emergency department were 70,693 (47.3%), whereas 43,125 patients (28.8%) were administered PN in intensive care units. In the adult PN patients, the highest primary diagnosis was malignant neoplasm of the stomach (8,911, 6.0%), followed by organism unspecified pneumonia (7,008, 4.7%), and gastroenteritis and colitis of unspecified origin (6,381, 4.3%). Overall, 34% of adult PN patients were diagnosed with malignancies, the most common being neoplasm of the stomach (17.7%), neoplasm of bronchus/lung (11.2%), neoplasm of colon (11.1%), and neoplasm of liver/intrahepatic bile ducts (10.0%). PN solutions were most frequently administered in the metropolitan area (55.0%) and in hospitals with more than 1,000 beds (23.6%). Conclusion: PN was commonly administered in older patients, with primary diagnosis of malignancy in a significant number of cases. This study is the first large-scale description of PN-prescribing patterns in real-world clinical practice in South Korea.

Keywords

Acknowledgement

Supported by : National Research Foundation of Korea (NRF)

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