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Esophageal Basaloid Squamous Carcinoma Treated by Endoscopic Resection and Radiation

내시경 절제술과 방사선 치료로 완치한 식도의 기저양 편평세포암

  • Kim, Sung Bum (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Lee, Si Hyung (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Jeong, Da Eun (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Kim, Kyeong Ok (Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Gu, Mi Jin (Department of Pathology, Yeungnam University College of Medicine)
  • 김승범 (영남대학교 의과대학 내과학교실) ;
  • 이시형 (영남대학교 의과대학 내과학교실) ;
  • 정다은 (영남대학교 의과대학 내과학교실) ;
  • 김경옥 (영남대학교 의과대학 내과학교실) ;
  • 구미진 (영남대학교 의과대학 병리학교실)
  • Received : 2018.05.09
  • Accepted : 2018.07.01
  • Published : 2018.11.25

Abstract

Esophageal basaloid squamous carcinoma (BSC) is a rare, aggressive variant of squamous cell carcinoma. BSC is usually diagnosed in advanced stage and its prognosis is relatively poor. A 59-year-old male with subepithelial lesion of the esophagus that was incidentally discovered during health promotion examination was referred to our hospital. Esophagogastroduodenoscopy showed a 10-mm bulging mucosa with an intact surface at 34 cm from incisor teeth. Endoscopic ultrasonography revealed a smooth margined homogenous hypoechoic lesion, measuring $11.3{\times}3.9mm$ with a submucosal layer of origin. The patient underwent endoscopic mucosal resection of the subepithelial lesion. Pathologic examination of the resected specimen revealed BSC with involvement of vertical margin by tumor. The patient then underwent radiotherapy, and is doing well without recurrence for 35 months. We report a case of esophageal BSC confined to submucosal layer successfully treated with endoscopic resection followed by radiation.

Keywords

Acknowledgement

Supported by : Yeungnam University

References

  1. Cho KJ, Jang JJ, Lee SS, Zo JI. Basaloid squamous carcinoma of the oesophagus: a distinct neoplasm with multipotential differentiation. Histopathology 2000;36:331-340. https://doi.org/10.1046/j.1365-2559.2000.00851.x
  2. Zhang BH, Cheng GY, Xue Q, et al. Clinical outcomes of basaloid squamous cell carcinoma of the esophagus: a retrospective analysis of 142 cases. Asian Pac J Cancer Prev 2013;14:1889-1894. https://doi.org/10.7314/APJCP.2013.14.3.1889
  3. Seremetis MG, Lyons WS, deGuzman VC, Peabody JW Jr. Leiomyomata of the esophagus. An analysis of 838 cases. Cancer 1976;38:2166-2177. https://doi.org/10.1002/1097-0142(197611)38:5<2166::AID-CNCR2820380547>3.0.CO;2-B
  4. Eckardt AJ, Wassef W. Diagnosis of subepithelial tumors in the GI tract. Endoscopy, EUS, and histology: bronze, silver, and gold standard? Gastrointest Endosc 2005;62:209-212. https://doi.org/10.1016/j.gie.2005.05.001
  5. Japanese Society for Esophageal Disease. Guidelines for clinical and pathologic studies on carcinoma of the esophagus, ninth edition: preface, general principles, part I. Esophagus 2004;1:61-88.
  6. Arai T, Aida J, Nakamura K, Ushio Y, Takubo K. Clinicopathologic characteristics of basaloid squamous carcinoma of the esophagus. Esophagus 2011;8:169. https://doi.org/10.1007/s10388-011-0280-x
  7. Nakamura M, Nishikawa J, Suenaga S, et al. A case of EMRC for basaloid squamous carcinoma of the cervical esophagus. World J Gastrointest Endosc 2012;4:373-375. https://doi.org/10.4253/wjge.v4.i8.373