Mood & Emotion (우울조울병)

Korean Society for Affective Disorders (대한우울조울병학회)
권호 표지

Korean Medication Algorithm for Bipolar Disorder 2018 : Children and Adolescents

한국형 양극성 장애 약물치료 알고리듬 2018 : 소아/청소년

  • Shim, Se-Hoon (Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University) ;
  • Bahk, Won-Myong (Department of Psychiatry, College of Medicine, The Catholic University of Korea) ;
  • Yoon, Bo-Hyun (Department of Psychiatry, Naju National Hospital) ;
  • Jon, Duk-In (Department of Psychiatry, Sacred Heart Hospital, Hallym University) ;
  • Seo, Jeong Seok (Department of Psychiatry, School of Medicine, Konkuk University) ;
  • Kim, Won (Department of Psychiatry, Seoul Paik Hospital, College of Medicine, Inje University) ;
  • Lee, Jung Goo (Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University and Paik Institute for Clinical Research and Department of Health Science and Technology, Graduate School of Inje University) ;
  • Woo, Young Sup (Department of Psychiatry, College of Medicine, The Catholic University of Korea) ;
  • Jeong, Jong-Hyun (Department of Psychiatry, College of Medicine, The Catholic University of Korea) ;
  • Kim, Moon-Doo (Department of Psychiatry, Jeju National University Hospital) ;
  • Sohn, Inki (Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation) ;
  • Song, Hoo-Rim (Department of Psychiatry, Myongji Hospital) ;
  • Min, Kyung Joon (Department of Psychiatry, College of Medicine, Chung-Ang University)
  • 심세훈 (순천향대학교 의과대학 천안병원 정신건강의학과) ;
  • 박원명 (가톨릭대학교 의과대학 정신과학교실) ;
  • 윤보현 (국립나주병원 정신건강의학과) ;
  • 전덕인 (한림대학교 의과대학 성심병원 정신건강의학과) ;
  • 서정석 (건국대학교 의학전문대학원 충주병원 정신건강의학과) ;
  • 김원 (인제대학교 의과대학 서울백병원 정신건강의학과) ;
  • 이정구 (인제대학교 의과대학 해운대백병원 정신건강의학과 및 백인제기념 임상의학연구소, 인제대학교 대학원 융합의과학) ;
  • 우영섭 (가톨릭대학교 의과대학 정신과학교실) ;
  • 정종현 (가톨릭대학교 의과대학 정신과학교실) ;
  • 김문두 (제주대학교병원 정신건강의학과) ;
  • 손인기 (계요의료재단 계요병원 정신건강의학과) ;
  • 송후림 (명지병원 정신건강의학과) ;
  • 민경준 (중앙대학교 의과대학 정신건강의학과교실)
  • Received : 2018.10.05
  • Accepted : 2018.10.14
  • Published : 2018.11.30

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Abstract

Objectives : The objective of this study was to revise the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) 2014: Children and Adolescents. Methods : We performed the survey, using a questionnaire comprising 22 questions according to each situation, in children and adolescents with bipolar disorder. Results : First-line pharmacotherapeutic strategies for manic episode in children with bipolar disorder were a combination of mood stabilizer (MS) and an atypical antipsychotics (AAP), monotherapy with an AAP, risperidone, and aripiprazole. Aripiprazole was selected as first-line medication for depressive episode in children with bipolar disorder, and aripiprazole, and risperidone were selected as first-line at high-risk children. First-line pharmacotherapeutic strategies for manic episode in adolescents were a combination of MS and an AAP, monotherapy with an AAP valproate, lithium, risperidone (Treatment of Choice, TOC), aripiprazole, and quetiapine. First-line pharmacotherapeutic strategies for depressive episode in adolescents, were a combination of an atypical antipsychotics and lamotrigine, valproate, aripiprazole (TOC), risperidone, and quetiapine. For depressive episodes in adolescents at high risk for bipolar disorder, valproate, aripiprazole (TOC), and risperidone were selected as first-line medication. Conclusion : We expect that the present KMAP-BP 2018-children and adolescents, is useful for clinicians to treat children and adolescents with bipolar disorder.

Keywords

Acknowledgement

Supported by : 대한우울.조울병학회, 대한정신약물학회

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