DOI QR코드

DOI QR Code

Do Toll-like Receptors Play a New Role as a Biomarker of Irritable Bowel Syndrome?

  • Kim, Hyun Jin (Department of Internal Medicine, Gyeongsang National University Changwon Hospital)
  • Received : 2018.09.11
  • Accepted : 2018.09.13
  • Published : 2018.10.30

Abstract

Keywords

References

  1. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006;130:1480-1491. https://doi.org/10.1053/j.gastro.2005.11.061
  2. Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA 2015;313:949-958. https://doi.org/10.1001/jama.2015.0954
  3. Rodriguez-Fandino O, Hernandez-Ruiz J, Schmulson M. From cytokines to toll-like receptors and beyond - current knowledge and future research needs in irritable bowel syndrome. J Neurogastroenterol Motil 2010;16:363-373. https://doi.org/10.5056/jnm.2010.16.4.363
  4. Ohman L, Isaksson S, Lindmark AC, et al. T-cell activation in patients with irritable bowel syndrome. Am J Gastroenterol 2009;104:1205-1212. https://doi.org/10.1038/ajg.2009.116
  5. Cremon C, Gargano L, Morselli-Labate AM, et al. Mucosal immune activation in irritable bowel syndrome: gender dependence and association with digestive symptoms. Am J Gastroenterol 2009;104:392-400. https://doi.org/10.1038/ajg.2008.94
  6. Barbara G, De Giorgio R, Stanghellini V, Cremon C, Corinaldesi R. A role for inflammation in irritable bowel syndrome? Gut 2002;51(suppl 1):i41-i44. https://doi.org/10.1136/gut.51.suppl_1.i41
  7. Kassinen A, Krogius-Kurikka L, Makivuokko H, et al. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology 2007;133:24-33. https://doi.org/10.1053/j.gastro.2007.04.005
  8. Camilleri M, Gorman H. Intestinal permeability and irritable bowel syndrome. Neurogastroenterol Motil 2007;19:545-552. https://doi.org/10.1111/j.1365-2982.2007.00925.x
  9. Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1:135-145. https://doi.org/10.1038/35100529
  10. Shukla R, Ghosahl U, Ranjan P, Ghoshal UC. Expression of toll-like receptors, pro-, and anti-inflammatory cytokines in relation to gut microbiota in irritable bowel syndrome: the evidence for its micro-organic basis. J Neurogastroenterol Motil 2018;24:628-642. https://doi.org/10.5056/jnm18130

Cited by

  1. Crosstalk Between Intestinal Serotonergic System and Pattern Recognition Receptors on the Microbiota-Gut-Brain Axis vol.12, pp.None, 2021, https://doi.org/10.3389/fendo.2021.748254
  2. Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders vol.22, pp.18, 2018, https://doi.org/10.3390/ijms221810134
  3. Modified Renshen Wumei Decoction Alleviates Intestinal Barrier Destruction in Rats with Diarrhea vol.31, pp.9, 2021, https://doi.org/10.4014/jmb.2106.06037