대한전해질대사연구회지 (Electrolytes & blood pressure)

  • 제16권2호
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  • Pages.23-26
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  • 2018
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  • 1738-5997(pISSN)
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  • 2092-9935(eISSN)
전해질고혈압연구회 (The Korean Society of Electrolyte Metabolism)
권호 표지
DOI QR코드

DOI QR Code

Long-term Tolvaptan Treatment of Autosomal Dominant Polycystic Kidney Disease in Korea

  • Kim, Ha Yeon (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Lee, Seung Jin (Department of radiology, Chonnam National University Medical School) ;
  • Kim, Byung Ki (Department of Internal Medicine, Saint Carollo Hospital) ;
  • Kim, Minah (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Bae, Eun Hui (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Ma, Seong Kwon (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Soo Wan (Department of Internal Medicine, Chonnam National University Medical School)
  • 투고 : 2018.12.04
  • 심사 : 2019.02.26
  • 발행 : 2018.12.30
⟨ 이전 논문 다음 논문 ⟩

초록

A 22-year-old male patient was diagnosed with autosomal dominant polycystic kidney disease (ADPKD). He received conservative treatment with an angiotensin-converting enzyme inhibitor. Two years later, oral therapy, consisting of 60 mg tolvaptan per day, was initiated. Compared with height-adjusted total kidney volume, the rate of kidney growth reduced significantly from 7.33% to 0.66% annually, since commencement of the tolvaptan therapy. The liver enzyme profile and serum sodium level and osmolality were constantly within normal ranges. In Korea, this is the first reported case of a patient with ADPKD who received tolvaptan treatment for more than 1 year. This case demonstrates that long-term tolvaptan treatment appears to be safe, well tolerated, and effective for ADPKD.

키워드

과제정보

연구 과제 주관 기관 : Chonnam National University Hospital

참고문헌

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