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Analysis of Relationship between Reflux Symptom Index and Psychiatric Problems

역류증상지수와 정신과적 질환과의 상관관계 분석

  • Park, In-Jun (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Kang, Jun-Myung (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Seo, Jae-Hyun (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Hwang, Se-Hwan (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Youn, Ho-Young (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Jin, Ho-Jun (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Kang, Ha-Ram (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Joo, Young-Hoon (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea)
  • 박인준 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 강준명 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 서재현 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 황세환 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 윤호영 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 진호준 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 강하람 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 주영훈 (가톨릭대학교 의과대학 이비인후과학교실)
  • Received : 2017.07.28
  • Accepted : 2018.08.01
  • Published : 2018.12.25

Abstract

Background and Objectives This study investigated the relationship between reflux symptom index (RSI) and psychiatric problems such as depression, somatization, and anxiety. Subjects and Method We prospectively analyzed 231 patients with symptoms with laryngopharyngeal reflux (LPR) using the RSI and the reflux finding score. Results Seventy nine patients (34.2%) were diagnosed with LPR. A significant correlation was detected between the RSI and depression ($18.4{\pm}8.3$ vs. $12.3{\pm}7.0$, p<0.001), anxiety ($19.5{\pm}8.5$ vs. $13.0{\pm}7.3$, p<0.001), and somatization ($19.2{\pm}9.1$ vs. $13.6{\pm}7.5$, p<0.001). A multivariate analysis confirmed a significant association between heartburn and depression [odds ratio (OR): 1.241, 95% confidence interval (CI): 1.003-1.537, p=0.047], choking and anxiety (OR: 1.747, 95% CI: 1.297-2.352, p<0.001), and choking and somatization (OR: 1.707, 95% CI: 1.248-2.336, p=0.001). Conclusion Our preliminary results suggest that patients with high RSI may need to be carefully evaluated for psychiatric problems.

Keywords

References

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