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National Trends in Smoking Cessation Medication Prescriptions for Smokers With Chronic Obstructive Pulmonary Disease in the United States, 2007-2012

  • Kwak, Min Ji (Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston) ;
  • Kim, Jongoh (Department of Medicine, Baylor College of Medicine) ;
  • Bhise, Viraj (Department of Management Policy and Community Health, University of Texas School of Public Health) ;
  • Chung, Tong Han (Healthcare Transformation Initiatives, McGovern Medical School, University of Texas Health Science Center at Houston) ;
  • Petitto, Gabriela Sanchez (Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston)
  • 투고 : 2018.05.25
  • 심사 : 2018.08.23
  • 발행 : 2018.09.30

초록

Objectives: Smoking cessation decreases morbidity and mortality due to chronic obstructive pulmonary disease (COPD). Pharmacotherapy for smoking cessation is highly effective. However, the optimal prescription rate of smoking cessation medications among smokers with COPD has not been systemically studied. The purpose of this study was to estimate the national prescription rates of smoking cessation medications among smokers with COPD and to examine any disparities therein. Methods: We conducted a retrospective study using National Ambulatory Medical Care Survey data from 2007 to 2012. We estimated the national prescription rate for any smoking cessation medication (varenicline, bupropion, and nicotine replacement therapy) each year. Multiple survey logistic regression was performed to characterize the effects of demographic variables and comorbidities on prescriptions. Results: The average prescription rate of any smoking cessation medication over 5 years was 3.64%. The prescription rate declined each year, except for a slight increase in 2012: 9.91% in 2007, 4.47% in 2008, 2.42% in 2009, 1.88% in 2010, 1.46% in 2011, and 3.67% in 2012. Hispanic race and depression were associated with higher prescription rates (odds ratio [OR], 5.15; 95% confidence interval [CI], 1.59 to 16.67 and OR, 2.64; 95% CI, 1.26 to 5.51, respectively). There were no significant differences according to insurance, location of the physician, or other comorbidities. The high OR among Hispanic population and those with depression was driven by the high prescription rate of bupropion. Conclusions: The prescription rate of smoking cessation medications among smokers with COPD remained low throughout the study period. Further studies are necessary to identify barriers and to develop strategies to overcome them.

키워드

참고문헌

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피인용 문헌

  1. Secular trends in smoking in relation to prevalent and incident smoking-related disease: A prospective population-based study vol.17, pp.10, 2018, https://doi.org/10.18332/tid/112459
  2. Polypharmacy among Older Individuals with COPD: Trends between 2000 and 2015 in Quebec, Canada vol.16, pp.3, 2018, https://doi.org/10.1080/15412555.2019.1646716
  3. Tobacco Screening and Treatment of Patients With a Psychiatric Diagnosis, 2012–2015 vol.57, pp.5, 2018, https://doi.org/10.1016/j.amepre.2019.06.009