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A Case of Metronidazole-Induced Encephalopathy: Atypical Involvement of the Brain on MRI

  • Hwang, Eunjin (Department of Radiology, Hallym University Dongtan Sacred Heart Hospital) ;
  • Chang, Suk-Ki (Department of Radiology, Hallym University Dongtan Sacred Heart Hospital) ;
  • Lee, Seun-Ah (Department of Radiology, Hallym University Dongtan Sacred Heart Hospital) ;
  • Choi, Jung-Ah (Department of Radiology, Hallym University Dongtan Sacred Heart Hospital)
  • Received : 2018.05.07
  • Accepted : 2018.06.23
  • Published : 2018.09.30

Abstract

Metronidazole is an antimicrobial agent widely used for the treatment of anaerobic infection or antibiotics-associated diarrhea. It is generally thought to be safe, but can induce reversible toxic encephalopathy in the case of excessive or cumulative over-dose. Metronidazole-induced encephalopathy generally demonstrates the characteristic features of typical lesion location and bilaterality on magnetic resonance imaging (MRI). We report a case of metronidazole-induced encephalopathy with the involvement of asymmetric white matter. To our knowledge, only a few cases have been reported with respect to white matter lesion characteristics on MRI with diffusion-weighted images.

Keywords

References

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