Usefulness of Customized Cervical Spine Immobilizer in Head & Neck Image-Guided Radiation Therapy with Tomotherapy®

토모테라피를 이용한 두경부암 영상유도 방사선 치료 시 개인별 경추고정용구의 유용성 평가

  • Jin, Sung Eun (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Chang, Se Wuk (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Choi, Jung Hoan (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Kim, Min Joo (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Ahn, Seung Kwon (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Lee, Sang Kyu (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
  • Cho, Jung Heui (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine)
  • 진성은 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 장세욱 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 최정환 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 김민주 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 안승권 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 이상규 (연세대학교 의과대학 연세암병원 방사선종양학과) ;
  • 조정희 (연세대학교 의과대학 연세암병원 방사선종양학과)
  • Published : 2018.12.29

Abstract

Purpose : Standardized pillow may not support patient's individual cervical spine thoroughly when head and neck radiation therapy with $Tomotherapy^{(R)}$. Therefore, the purpose of this study was to make a comparative analysis for the difference of using standardized pillow only and using customized cervical spine immobilizer with standardized pillow. Materials and Methos : The head and neck cancer patients who are treated image-guided radiation therapy(IGRT) with $Tomotherapy^{(R)}$ were divided into two groups, 20 patients using standardized pillow only, and 20 patients using customized cervical spine immobilizer with standardized pillow. We achieved 20 mega-voltage computed tomography(MVCT) image per patient, compared curvature of the cervical spine in MVCT with curvature of the cervical spine in CT-simulation. Results : Results of comparative analysis were curvature consistency 95.9 %, maximum error of distance 41.9 mm, average distance error per fractionation 19.4 mm, average standard deviation 1.34 mm in case of using standardized pillow only, curvature consistency 98.9 %, maximum error of distance 12.9 mm, average distance error per fractionation 5.8 mm, average standard deviation 0.59 mm in case of using customized cervical spine immobilizer with standardized pillow. Conclusion : Using customized cervical spine immobilizer shows higher reproducibility and low distance error, therefore customized cervical spine immobilizer could be useful for head and neck cancer patients who need radiation therapy.

목 적 : 두경부암 방사선 치료 시 사용되는 규격화된 기성 베개에 개인별 경추고정용구를 적용하여 개인별 경추고정용구의 유용성을 평가하고자 한다. 대상 및 방법 : 본원에서 토모테라피를 이용한 두경부암 치료 환자 중 기성 베개만을 사용한 환자와 개인별 경추고정용구를 적용한 환자 각각 20명을 대상으로 환자 당 20회 치료 시 획득한 MVCT 영상을 토모테라피 영상유도 프로그램으로 자동 보정한 영상을 바탕으로 2번 경추 최하단부부터 발쪽으로 6.7 cm까지 10분할하여 각 분할 당 경추 위치 값을 치료설계 시의 경추 위치 값과 비교하였다. 결 과 : 개인별 경추고정용구를 적용한 경우 50 mm 기준 경추만곡도 일치율은 평균 98.9 %, 최대오차 평균 12.9 mm, 1회 치료 당 평균 오차 5.8 mm, 표준편차 평균 0.59 mm로 측정되었고 개인별 경추고정용구를 적용하지 않았을 경우 경추만곡 일치율은 평균 95.9 %, 최대오차 평균 41.9 mm, 1회 치료 당 평균 오차 19.4 mm, 표준편차 평균 1.34 mm로 측정되었다. 결 론 : 두경부 암 방사선 치료 시 개인별 경추고정용구 적용이 필요할 것으로 사료된다.

Keywords

References

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