Altered Gravity and Immune Response

중력 변화의 면역계에 대한 영향

  • Jang, Tae Young (Institute of Aerospace Biomedical Science and Technology, Inha University) ;
  • Kim, Kyu-Sung (Institute of Aerospace Biomedical Science and Technology, Inha University) ;
  • Kim, Young Hyo (Institute of Aerospace Biomedical Science and Technology, Inha University)
  • 장태영 (인하대학교 우주항공의생명과학연구소) ;
  • 김규성 (인하대학교 우주항공의생명과학연구소) ;
  • 김영효 (인하대학교 우주항공의생명과학연구소)
  • Received : 2018.04.16
  • Accepted : 2018.04.19
  • Published : 2018.04.30

Abstract

It is essential to study the effects of hypergravity on the human body in the research field of aerospace medicine. Previous studies have shown that hypergravity could act in a harmful way to the human body. However, recent studies have shown that moderate degree of hypergravity can act in a beneficial way to the human body. The authors have in particular been studying the effects of hypergravity on immune diseases, especially allergic asthma and rhinitis. Therefore, this review paper will introduce the results of recent studies on hormetic (health promotion) effect of hypergravity. In addition, this review paper also examines the mechanism by which hormetic effect of hypergravity could be possible. Furthermore, we will also discuss how to apply these hormetic effects in clinical practice.

Keywords

Acknowledgement

This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science, and Technology (NRF-2017R1C1B2001989).