대한피부과학회지 (Korean journal of dermatology)

  • 제56권10호
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  • Pages.636-639
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  • 2018
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  • 0494-4739(pISSN)
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  • 2713-7627(eISSN)
대한피부과학회 (Korean Dermatological Association)
권호 표지

Mycosis Fungoides Responsive to Oral Alitretinoin and Ultraviolet B Phototherapy: A Case Report

  • Han, Song Hee (Department of Dermatology, Konkuk University School of Medicine) ;
  • Hong, Ji Youn (Department of Dermatology, Konkuk University School of Medicine) ;
  • Hong, Joo Ran (Department of Dermatology, Konkuk University School of Medicine) ;
  • Hur, Min Seok (Department of Dermatology, Konkuk University School of Medicine) ;
  • Youn, Hae Jeong (Department of Dermatology, Konkuk University School of Medicine) ;
  • Lee, Yang Won (Department of Dermatology, Konkuk University School of Medicine) ;
  • Choe, Yong Beom (Department of Dermatology, Konkuk University School of Medicine) ;
  • Ahn, Kyu Joong (Department of Dermatology, Konkuk University School of Medicine)
  • 투고 : 2017.08.24
  • 심사 : 2018.01.23
  • 발행 : 2018.12.31
⟨ 이전 논문 다음 논문 ⟩

초록

Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. Patients with early stage disease usually respond well to conventional therapies, with a relatively favorable prognosis. However, a few patients are refractory to treatment and need alternative strategies, even at the patch and plaque stages. We report the case of a middle-aged woman with long-standing and refractory mycosis fungoides that responded to combination therapy with the 308-nm excimer laser and oral alitretinoin.

키워드

참고문헌

  1. Korgavkar K, Xiong M, Weinstock M. Changing incidence trends of cutaneous T-cell lymphoma. JAMA Dermatol 2013;149:1295-1299 https://doi.org/10.1001/jamadermatol.2013.5526
  2. Kaye FJ, Bunn PA Jr, Steinberg SM, Stocker JL, Ihde DC, Fischmann AB, et al. A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides. N Engl J Med 1989;321:1784-1790 https://doi.org/10.1056/NEJM198912283212603
  3. Woo YR, Lee HM, Lee JS, Koo DW. Long-term follow-up of refractory mycosis fungoides which achieved remission with the addision of isotretinoin to methotrexate and psoralen plus ultraviolat a therapy. Ann Dermatol 2013;25:259-260 https://doi.org/10.5021/ad.2013.25.2.259
  4. Trautinger F, Eder J, Assaf C, Bagot M, Cozzio A, Dummer R, et al. European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Sezary syndrome-update 2017. Eur J Cancer 2017;77:57-74 https://doi.org/10.1016/j.ejca.2017.02.027
  5. Shin HS, Huh CH, Cho KH. Treatment of the early mycosis fungoides. Korean J Dermatol 2007;45:983-988
  6. Huang J, Cowper S, Moss J, Girardi M. Case experience of 308-nm excimer laser therapy compatibility with PUVA and oral bexarotene for the treatment of cutaneous lesions in mycosis fungoides. J Drugs Dermatol 2013;12:487-489
  7. Deaver D, Cauthen A, Cohen G, Sokol L, Glass F. Excimer laser in the treatment of mycosis fungoides. J Am Acad Dermatol 2014;70:1058-1060 https://doi.org/10.1016/j.jaad.2014.01.915
  8. Beckenbach L, Baron JM, Merk HF, Loffler H, Amann PM. Retinoid treatment of skin diseases. Eur J Dermatol 2015;25:384-391
  9. Coors EA, von den Driesch P. Treatment of 2 patients with mycosis fungoides with alitretinoin. J Am Acad Dermatol 2012;67:e265-267 https://doi.org/10.1016/j.jaad.2012.05.011
  10. Kapser C, Herzinger T, Ruzicka T, Flaig M, Molin S. Treatment of cutaneous T-cell lymphoma with oral alitretinoin. J Eur Acad Dermatol Venereol 2015;29:783-788 https://doi.org/10.1111/jdv.12684
  11. Kunz M, Urosevic-Maiwald M, Goldinger SM, Frauchiger AL, Dreier J, Belloni B, et al. Efficacy and safety of oral alitretinoin in severe oral lichen planus--results of a prospective pilot study. J Eur Acad Dermatol Venereol 2016;30:293-298 https://doi.org/10.1111/jdv.13444
  12. Ruzicka T, Larsen FG, Galewicz D, Horvath A, Coenraads PJ, Thestrup-Pedersen K, et al. Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebo-controlled, multicenter trial. Arch Dermatol 2004;140:1453-1459
  13. Diepgen TL, Pfarr E, Zimmermann T. Efficacy and tolerability of alitretinoin for chronic hand eczema under daily practice conditions: results of the TOCCATA open study comprising 680 patients. Acta Derm Venereol 2012;92:251-255 https://doi.org/10.2340/00015555-1256