Multiple Microvenular Hemangioma Clinicopathologically Mimicking Early Stage Kaposi Sarcoma: A Case Report

초기 단계의 카포시육종과 임상조직학적으로 유사한 다발성미세소정맥혈관종 1예

  • Eun, Dong Hyuk (Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital) ;
  • Kim, Seok Min (Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital) ;
  • Kim, Jun Young (Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital) ;
  • Han, Man-Hoon (Department of Pathology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital) ;
  • Lee, Seok-Jong (Department of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital)
  • 은동혁 (경북대학교 의학전문대학원 피부과학교실) ;
  • 김석민 (경북대학교 의학전문대학원 피부과학교실) ;
  • 김준영 (경북대학교 의학전문대학원 피부과학교실) ;
  • 한만훈 (경북대학교 의학전문대학원 병리학교실) ;
  • 이석종 (경북대학교 의학전문대학원 피부과학교실)
  • Received : 2017.11.06
  • Accepted : 2018.02.07
  • Published : 2018.12.31

Abstract

Microvenular hemangioma (MVH) is a rare acquired benign vascular neoplasm, which presents commonly as a solitary purple-to-red nodule or plaque measuring approximately 10 mm in diameter. MVH occurs primarily on the extremities or the trunk. Most lesions are solitary, and multiple lesions are rare. Histopathological features of MVH include numerous, scattered, thin and irregularly branching small vessels in the dermis and endothelial cells without atypia. Owing to similarities in clinical morphology and histopathological features, MVH may often be indistinguishable from the early patch stage of Kaposi sarcoma. Immunohistochemical (IHC) analysis helps differentiate between the 2 diseases. The results of IHC tests in patients with MVH show positive staining for CD31 and smooth muscle actin and typically, negative staining for the human herpes virus 8 antigen. We report a rare case of multiple MVH clinically mimicking the early patch stage of Kaposi sarcoma in a 63-year-old woman who presented with a 3-year history of slowly growing, compressible, soft, bluish-purple macules and plaques on the trunk and right arm.

Keywords

References

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