The Korean Journal of Oral and Maxillofacial Pathology (대한구강악안면병리학회지)

Korean Academy of Oral and Maxillofacial Pathology (대한구강악안면병리학회)
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Undifferentiated Pleomorphic Sarcoma in the Mandibular Ramus and Post-Operative Recurrence: A Case Report

하악지 영역에 발생한 미분화성 다형성 육종: 수술 후 재발한 증례

  • Ahn, Jaemyung (Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jang, Seung-Il (Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hong, Jongrak (Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Paeng, Jun Young (Department of Oral and Maxillofacial Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 안재명 (성균관대학교 의과대학 삼성서울병원 구강악안면외과) ;
  • 장승일 (성균관대학교 의과대학 삼성서울병원 구강악안면외과) ;
  • 홍종락 (성균관대학교 의과대학 삼성서울병원 구강악안면외과) ;
  • 팽준영 (성균관대학교 의과대학 삼성서울병원 구강악안면외과)
  • Received : 2018.09.19
  • Accepted : 2018.10.19
  • Published : 2018.10.31
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Abstract

Undifferentiated pleomorphic sarcoma (UPS) in the mandible region is a rare malignant neoplasm. We encountered the case of a patient who had been diagnosed with deep benign fibrous histiocytoma (DBFH) prior to surgery, but the final biopsy revealed the presence of tumor tissues in the resected margin, which indicated a UPS. Therefore, radiotherapy was conducted post-operatively, but the tumor recurred approximately 3 years later and a second surgery was performed. The difference between the initial and final diagnoses was considered to be due to the characteristics of the tumor, as it involved both benign and malignant components. DBFH and UPS can occur in young women. DBFH can transform to a malignancy and UPS may also appear as a benign tumor during early biopsy. Hence, attention should be paid to diagnosis and treatment methods, and ongoing close observation is required.

Keywords

References

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