DOI QR코드

DOI QR Code

Improvement Effect of the HyungGae-Water on Quality of Life in Children and Adolescents with Pruritus

한방입욕제(형개수) 사용을 통한 소양증을 호소 소아청소년의 삶의 질 개선효과

  • Jeong, Kyung Sik (Future Medicine Division, Korea Institute of Oriental Medicine) ;
  • Baek, Young Hwa (Future Medicine Division, Korea Institute of Oriental Medicine) ;
  • Yoo, Jong Hyang (Future Medicine Division, Korea Institute of Oriental Medicine) ;
  • Hwang, Man Ki (Seocho Inuri Korean Medicine Clinic) ;
  • Choi, Young Jin (Kyung Hee Dabok Korean Medicine Clinic) ;
  • Kim, Yun Hee (College of Korean Medicine, Daejeon University) ;
  • Lee, Si Woo (Future Medicine Division, Korea Institute of Oriental Medicine)
  • 정경식 (한국한의학연구원 미래의학부) ;
  • 백영화 (한국한의학연구원 미래의학부) ;
  • 유종향 (한국한의학연구원 미래의학부) ;
  • 황만기 (서초아이누리한의원) ;
  • 최영진 (경희다복한의원) ;
  • 김윤희 (대전대학교 한의과대학 한방소아과) ;
  • 이시우 (한국한의학연구원 미래의학부)
  • Received : 2018.01.25
  • Accepted : 2018.06.07
  • Published : 2018.06.25

Abstract

Pruritus is the most prominent symptom of atopic dermatitis and other skin diseases. It is not easily improved and is a major factor that threatens the quality of life of patients and their families. The purpose of this study was to evaluate the effect of HyungGae-Water, which was bath preparation made from Korean medicine herbs, for children and adolescents suffering pruritus. The participants were 50 boys and girls aged from 2 to 15 years old. The HyungGae-Water was used once a day for 6 weeks, and we were followed up three times every two weeks. Of 50 participants enrolled, 47 completed the study. The outcome variables were dermatology quality of life scales in children, pruritus VAS, and investigator global assessment (IGA). The results of the study show that the dermatology quality of life is significantly improved and the VAS of pruritus has meaningful changes. In the IGA, moderate or severe improvement was observed in 48.9% and slight improvement in 17%. There were seven suspected or less relevant adverse events using HyungGae-Water. The present results suggest that the HyungGae-Water has alleviating effect for the pruritus in children and adolescents.

Keywords

References

  1. Ikoma A, Steinhoff M, Stander S, Yosipovitch G, Schmelz M. The neurobiology of itch. Nature reviews neuroscience. 2006;7(7):535-47. https://doi.org/10.1038/nrn1950
  2. Shim WH, Song CH, Park HJ, Kim HS, Chin HW, Kim SH, et al. Clinical Character istics of Itch in Patients with Adult and Childhood Atopic Dermatitis. Korean J Dermatol. 2011;49(4):318-27.
  3. Lsheehan-Dare R, Henderson M, A Cotterill J. Anxiety and depression in patients with chronic urticaria and generalized pruritus. Br J Dermatol. 1990;123(6):769-74. https://doi.org/10.1111/j.1365-2133.1990.tb04195.x
  4. Hashiro M, Okumura M. Anxiety, depression and psychosomatic symptoms in patients with atopic dermatitis: comparison with normal controls and among groups of different degrees of severity. Journal of dermatological science. 1997;14(1):63-7. https://doi.org/10.1016/S0923-1811(96)00553-1
  5. Won CH, Hong SP. Pathophysiology and Therapy of Pruritus in Allergic and Atopic Disease. Korean J Asthma Allergy Clin Immunol. 2010;30(3):184-92.
  6. Shim WH, Mun JH, Jwa SW, Song M, Kim HS, Ko HC, et al. Clinical Study of Itch in Korean Patients with Chronic Idiopathic Uriticaria. Korean J Dermatol. 2012;50(8):679-87.
  7. Kang H. Recently developed therapeutic options for skin disorders. J Korean Med Assoc. 2012;55(5):475-83. https://doi.org/10.5124/jkma.2012.55.5.475
  8. Han SH, Kim JS, Jugn BK, Park SJ, Kim HW. Chae H, et al. Effects of the Korean Herbal Bathiing Candidates on Skin Lesions in Mice Model. Korean Journal of Oriental Medicine. 2010;16(3):107-13.
  9. Lee JP, Lee JK, Jeong HJ, Oh JK. Physical Science : The Effects of Oriental Herbal Bathing on Fatigue Recovery and Alternation of Physiological Factors in Athletes. Korean Sports Research. 2005;6(5):831-40.
  10. Jung BK, Park SJ. Kim JS, Han SH, Sohn KW, Yoon MY, et al. Study on the Antioxidative, Antiaging and Whitening Effects of Bathing Aid SP1 and SP2. J Physiol & Pathol Korean Med. 2010;24(5):837-42.
  11. Lee HL, Han JK, Kim YH. Analysis of Baby Bath Preparation. Journal of Korean Oriental Pediatrics. 2011;25(2):102-10.
  12. Kim JS, Han SH, Jung BK, Park SJ, Kim HW, Chae H, et al. Effects of the Korean Herbal Bathing Candidates on Allergic Contact or Wound Induced Dermatitis Mice Model. J Physiol & Pathol Korean Med. 2010;24(3):484-89.
  13. Jang MH, Choi JS, Choi AR, Ahn TW. Effects of Korean Herbal Bathing Extracts Composition on Th2 Cytokine Production in MC/9 Mast Cells. J Sasang Constit Med. 2012;24(3):80-92. https://doi.org/10.7730/JSCM.2012.24.3.80
  14. Lewis-Jones M, Finlay A. The Children's Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol. 1995;132(6):942-9. https://doi.org/10.1111/j.1365-2133.1995.tb16953.x
  15. Lewis-Jones M, Finlay A, Dykes P. The Infants' Dermatitis Quality of Life Index. Br J Dermatol. 2001;144:104-10. https://doi.org/10.1046/j.1365-2133.2001.03960.x
  16. Kim MB, Kim BJ, Seo YJ, Lee YW, Lee AY, Kim KH, et al. Skin Care for Atopic Dermatitis. Korean J Dermatol. 2009;47(5):531-8.
  17. Choi YY, Kim MH, Kum CJ, Choi YJ, Hwang MK, Sohn YJ, et al. Anti-inflammatory effects of HC001 on atopic dermatitis-like skin lesions in mice. Herbal formula science. 2012;20(1):1-9. https://doi.org/10.14374/HFS.2012.20.1.001
  18. Park DH, Bae HS. Lifestyle Habits and Characteristics of Atopic Dermatitis Occurred in Children. Kor J Aesthet Cosmetol. 2013;11(1):17-28.
  19. Lee JK, Lee HS, Ha JS, Park DJ, Paik DH, Ha KC. Prevalence Rate and Etiologic Risk Factors of Atopic Dermatitis in the Preschool Children in Changwon. J Envl Hlth Sci. 2009;35(3):169-77.
  20. Cho SI, Kim JH, Chung BY, Ahn IS, Kim HO, Park CW, et al. Quality of Life in Children and Adolescents with Atopic Dermatitis. Korean J Dermatol. 2011;49(5):415-21.
  21. Boguniewicz M, Zeichner JA, Eichenfield LF, Hebert AA, Jarratt M, Lucky AW, et al. MAS063DP is effective monotherapy for mild to moderate atopic dermatitis in infants and children: a multicenter, randomized, vehicle-controlled study. J Pediatr. 2008;152:854-9. https://doi.org/10.1016/j.jpeds.2007.11.031
  22. Lee HE, Im M, Lee Y, Lee JH, Seo YJ. Efficacy of Balneotherapy as an Adjuvant Treatment for Atopic Dermatitis at Yuseong Spa. Korean J Dermatol. 2014;52(2):82-8.

Cited by

  1. 인구통계학적 요인 및 나트륨 섭취와 건강관련 삶의 질 간의 연관성: 경주지역 성인을 중심으로 vol.36, pp.1, 2021, https://doi.org/10.7318/kjfc/2021.36.1.121