The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
권호 표지
DOI QR코드

DOI QR Code

A Correlation Study of Pattern Identification Instrument and Biomarkers for Polycystic Ovary Syndrome

다낭성난소증후군 변증도구와 생체지표 간의 상관성 연구

  • Park, Eun-Ji (Dept. of Obstetrics & Gynecology, College of Korean Medicine, DaeJeon University) ;
  • Baek, Seon-Eun (Dept. of Obstetrics & Gynecology, Dunsan Korean Medicine Hospital of Daejeon University) ;
  • Kang, Byoung-Kab (Clinical Medicine Division, Korea Institute of Oriental Medicine) ;
  • Yoo, Jeong-Eun (Dept. of Obstetrics & Gynecology, College of Korean Medicine, DaeJeon University) ;
  • Jung, In-Chul (Dept. of Oriental Neuropsychiatry, College of Korean Medicine, DaeJeon University)
  • 박은지 (대전대학교 한의과대학 부인과학교실) ;
  • 백선은 (대전대학교 둔산한방병원 여성의학과) ;
  • 강병갑 (한국한의학연구원 임상의학부) ;
  • 유정은 (대전대학교 한의과대학 부인과학교실) ;
  • 정인철 (대전대학교 한의과대학 한방신경정신과학교실)
  • Received : 2018.07.12
  • Accepted : 2018.08.22
  • Published : 2018.08.24
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to investigate the correlation between Pattern identification instrument and biomarkers in polycystic ovary syndrome patients. Methods: Pattern identification instrument questionnaire, Sasang constitutional test, body composition test, pulse analyzing test, laboratory test were performed and the results were analyzed. Correlation analysis was performed between pattern identification and laboratory test results. Results: Testosterone, SHBG, $17{\alpha}$-OH-progesterone, AMH were highest in the Kidney-Yang Deficiency (腎陽虛) group. LH, FSH, LH/FSH ratio were the highest in the Endogenous Heat due to Yin Deficiency (陰虛內熱) group. DHEA-S was the highest in the Dampness-Heat in Liver Meridian (肝經濕熱) group. E2, Prolactin, Cholesterol, Triglyceride, HDL-Cholesterol, LDL-Cholesterol, Glucose (FBS), Insulin, HOMA-IR ratio, HbA1c were the highest in the Phlegm-Dampness (痰濕) group. Conclusions: In this study, we obtained basic data analyzing the correlation between pattern identification instrument and biomarkers in polycystic ovary syndrome patients. If further studies are performed, we expect to be able to obtain clues to study the mechanism of polycystic ovary syndrome.

Keywords

References

  1. The complication committee of Gynecology. Gynecology. 2nd rev. ed. Seoul:Korea Medical Book Publishing Company. 2015:488-500.
  2. Chae SJ, et al. Polycystic Ovary Syndrome: 2003 Rotterdam Criteria, 2006 Androgen Excess Society. Journal of Reproductive Medicine and Population. 2009;22:7-12.
  3. Fauser BC, et al. Consensus on women's health aspects of polycystic ovary syndrome(PCOS): the Amsterdam ESHRE/ASRMSponsored 3rd PCOS Consensus Workshop Group. Fertil Steril. 2012;97(1):28-38. https://doi.org/10.1016/j.fertnstert.2011.09.024
  4. Shroff R, et al. Risk of metabolic complications in the new PCOS phenotypes based on the Rotterdam criteria. Fertil Steril. 2007;88(5):1389-95. https://doi.org/10.1016/j.fertnstert.2007.01.032
  5. Korean obstetrics & gynecology. Oriental obstetrics & gynecology(下). 2nd rev. ed. Seoul:Euiseongdang. 2012:225-33.
  6. Lai L, et al. Developing clinical practice guidelines for Chinese herbal treatment of polycystic ovary syndrome: a mixedmethods modified Delphi study. Complement Ther Med. 2015;23(3):430-8. https://doi.org/10.1016/j.ctim.2015.03.003
  7. Park EJ, et al. Preliminary Study on Development of Pattern Identification Instrument for Polycystic Ovarian Syndrome. J Korean Obstet Gynecol. 2017;30(1):68-84. https://doi.org/10.15204/jkobgy.2017.30.1.068
  8. Kim YY, Jang ES. Test-Retest Reliability of Brief KS-15- Korean Sasang Constitutional Diagnostic Questionnaire-. J Physiol & Pathol Korean Med. 2016;30(3):177-83. https://doi.org/10.15188/kjopp.2016.06.30.3.177
  9. Lee HJ, et al. Prevalence of Metabolic Syndrome in Young Korean Women with Polycystic Ovary Syndrome. DMJ. 2006;30(4):285-91.
  10. Lee IS, Cho HS, Kim JW. A Clinical Research on the Health Condition and the Etiology in Orienal Medicine of the High School Girls Menstrual Disorders by Sasang Constitution. J Korean Obstet Gynecol. 2014;27(3):41-65. https://doi.org/10.15204/JKOBGY.2014.27.3.041
  11. Kim KC, et al. Study on the character of the old aged pulsation. J Korea Instit Orient Med Diagn. 2009;12(2):1-7.
  12. The Korean Society of Gynecologic Endocrinology. Gynecologic Endocrinology. 1st rev. ed. Seoul:Koonja Publishing Inc. 2012:89-109.
  13. Yoo JH, et al. Age specific serum anti-Muerian hormone levels in 1,298 Korean women with regular menstruation. Clin Exp Reprod Med. 2011;38(2):93-7. https://doi.org/10.5653/cerm.2011.38.2.93
  14. Stracquadanio M, Ciotta L, Palumbo M. Relationship between serum anti-Mullerian hormone and intrafollicular AMH levels in PCOS women. Gynecol Endocrinol. 2018;34(3):223-8. https://doi.org/10.1080/09513590.2017.1381838
  15. Yin XD, He JQ. Study on Relativity between TCM Syndrome of PCOS and Sex Hormone. Liaoning Journal of Traditional Chinese Medicine. 2015;42(4):764-6.
  16. Li X, Zheng C, Hong Z. Correlation between sex hormone and insulin and various TCM syndrome types in patients with polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007;27(11):996-8.
  17. Fu H, et al. Spleen-Yang-deficiency patients with polycystic ovary syndrome have higher levels of visfatin. J Tradit Chin Med. 2014;34(1):42-7. https://doi.org/10.1016/S0254-6272(14)60052-2