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Dosimetric Plan Comparison of Accelerated Partial Breast Irradiation (APBI) Using CyberKnife

  • Lee, Chang Yeol (Department of Radiation Oncology, College of Medicine, Inha University) ;
  • Kim, Woo Chul (Department of Radiation Oncology, College of Medicine, Inha University) ;
  • Kim, Hun Jeong (Department of Radiation Oncology, College of Medicine, Inha University) ;
  • Lee, Jeongshim (Department of Radiation Oncology, College of Medicine, Inha University) ;
  • Park, Seungwoo (Research Institute of Radiological and Medical Sciences, Korea Institute of Radiological and Medical Sciences) ;
  • Huh, Hyun Do (Department of Radiation Oncology, College of Medicine, Inha University)
  • Received : 2018.06.14
  • Accepted : 2018.06.23
  • Published : 2018.06.30

Abstract

Accelerated partial breast irradiation (APBI) is a new treatment delivery technique that decreases overall treatment time by using higher fractional doses than conventional fractionation. Here, a quantitative analysis study of CyberKnife-based APBI was performed on 10 patients with left-sided breast cancer who had already finished conventional treatment at the Inha University Hospital. Dosimetric parameters for four kinds of treatment plans (3D-CRT, IMRT, VMAT, and CyberKnife) were analyzed and compared with constraints in the NSABP B39/RTOG 0413 protocol and a published CyberKnife-based APBI study. For the 10 patients recruited in this study, all the dosimetric parameters, including target coverage and doses to normal structures, met the NSABP B39/RTOG 0413 protocol. Compared with other treatment plans, a more conformal dose to the target and better dose sparing of critical structures were observed in CyberKnife plans. Accelerated partial breast irradiation via CyberKnife is a suitable treatment delivery technique for partial breast irradiation and offers improvements over external beam APBI techniques.

Keywords

References

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