Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Current Status of Interpretation of Small Bowel Capsule Endoscopy

  • Kim, Su Hwan (Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of Medicine) ;
  • Yang, Dong-Hoon (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Jin Su (Division of Gastroenterology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • Received : 2018.06.03
  • Accepted : 2018.07.18
  • Published : 2018.07.30
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Abstract

Capsule endoscopy (CE) has revolutionized direct small bowel imaging and is widely used in clinical practice. Remote visualization of bowel images enables painless, well-tolerated endoscopic examinations. Small bowel CE has a high diagnostic yield and the ability to examine the entire small bowel. The diagnostic yield of CE relies on lesion detection and interpretation. In this review, issues related to lesion detection and interpretation of CE have been addressed, and the current status of automated reading software development has been reviewed. Clinical significance of an external real-time image viewer has also been described.

Keywords

References

  1. Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy. Nature 2000;405:417.
  2. Eliakim R. Video capsule endoscopy of the small bowel. Curr Opin Gastroenterol 2013;29:133-139. https://doi.org/10.1097/MOG.0b013e32835bdc03
  3. McAlindon ME, Ching HL, Yung D, Sidhu R, Koulaouzidis A. Capsule endoscopy of the small bowel. Ann Transl Med 2016;4:369. https://doi.org/10.21037/atm.2016.09.18
  4. Saurin JC, Beneche N, Chambon C, Pioche M. Challenges and future of wireless capsule endoscopy. Clin Endosc 2016;49:26-29. https://doi.org/10.5946/ce.2016.49.1.26
  5. Koulaouzidis A, Iakovidis DK, Karargyris A, Plevris JN. Optimizing lesion detection in small-bowel capsule endoscopy: from present problems to future solutions. Expert Rev Gastroenterol Hepatol 2015;9:217-235. https://doi.org/10.1586/17474124.2014.952281
  6. Fisher LR, Hasler WL. New vision in video capsule endoscopy: current status and future directions. Nat Rev Gastroenterol Hepatol 2012;9:392-405. https://doi.org/10.1038/nrgastro.2012.88
  7. Goenka MK, Majumder S, Goenka U. Capsule endoscopy: present status and future expectation. World J Gastroenterol 2014;20:10024-10037. https://doi.org/10.3748/wjg.v20.i29.10024
  8. Singeap AM, Stanciu C, Trifan A. Capsule endoscopy: the road ahead. World J Gastroenterol 2016;22:369-378. https://doi.org/10.3748/wjg.v22.i1.369
  9. Barkin JA, Barkin JS. Video capsule endoscopy: technology, reading, and troubleshooting. Gastrointest Endosc Clin N Am 2017;27:15-27. https://doi.org/10.1016/j.giec.2016.08.002
  10. Triantafyllou K, Papanikolaou IS, Papaxoinis K, Ladas SD. Two cameras detect more lesions in the small-bowel than one. World J Gastroenterol 2011;17:1462-1467. https://doi.org/10.3748/wjg.v17.i11.1462
  11. Drew K, McAlindon ME, Sanders DS, Sidhu R. The nurse endoscopist: moving ahead with time. Gastroenterol Nurs 2013;36:209-213. https://doi.org/10.1097/SGA.0b013e31829545a3
  12. Hakim FA, Alexander JA, Huprich JE, Grover M, Enders FT. CT-enterography may identify small bowel tumors not detected by capsule endoscopy: eight years experience at Mayo Clinic Rochester. Dig Dis Sci 2011;56:2914-2919. https://doi.org/10.1007/s10620-011-1773-0
  13. Postgate A, Despott E, Burling D, et al. Significant small-bowel lesions detected by alternative diagnostic modalities after negative capsule endoscopy. Gastrointest Endosc 2008;68:1209-1214. https://doi.org/10.1016/j.gie.2008.06.035
  14. Zheng Y, Hawkins L, Wolff J, Goloubeva O, Goldberg E. Detection of lesions during capsule endoscopy: physician performance is disappointing. Am J Gastroenterol 2012;107:554-560. https://doi.org/10.1038/ajg.2011.461
  15. Pezzoli A, Cannizzaro R, Pennazio M, et al. Interobserver agreement in describing video capsule endoscopy findings: a multicentre prospective study. Dig Liver Dis 2011;43:126-131. https://doi.org/10.1016/j.dld.2010.07.007
  16. Shim KN, Jeon SR, Jang HJ, et al. Quality indicators for small bowel capsule endoscopy. Clin Endosc 2017;50:148-160. https://doi.org/10.5946/ce.2017.030
  17. Rajan E, Iyer PG, Oxentenko AS, et al. Training in small-bowel capsule endoscopy: assessing and defining competency. Gastrointest Endosc 2013;78:617-622. https://doi.org/10.1016/j.gie.2013.05.010
  18. Rondonotti E, Soncini M, Girelli CM, et al. Can we improve the detection rate and interobserver agreement in capsule endoscopy? Dig Liver Dis 2012;44:1006-1011. https://doi.org/10.1016/j.dld.2012.06.014
  19. Sidhu R, Sakellariou P, McAlindon ME, et al. Is formal training necessary for capsule endoscopy? The largest gastroenterology trainee study with controls. Dig Liver Dis 2008;40:298-302. https://doi.org/10.1016/j.dld.2007.11.022
  20. Niv Y, Niv G. Capsule endoscopy examination--preliminary review by a nurse. Dig Dis Sci 2005;50:2121-2124. https://doi.org/10.1007/s10620-005-3017-7
  21. Dokoutsidou H, Karagiannis S, Giannakoulopoulou E, et al. A study comparing an endoscopy nurse and an endoscopy physician in capsule endoscopy interpretation. Eur J Gastroenterol Hepatol 2011;23:166-170. https://doi.org/10.1097/MEG.0b013e3283433abf
  22. Lepileur L, Dray X, Antonietti M, et al. Factors associated with diagnosis of obscure gastrointestinal bleeding by video capsule enteroscopy. Clin Gastroenterol Hepatol 2012;10:1376-1380. https://doi.org/10.1016/j.cgh.2012.05.024
  23. Tacheci I, Deviere J, Kopacova M, Douda T, Bures J, Van Gossum A. The importance of upper gastrointestinal lesions detected with capsule endoscopy in patients with obscure digestive bleeding. Acta Gastroenterol Belg 2011;74:395-399.
  24. Buscaglia JM, Giday SA, Kantsevoy SV, et al. Performance characteristics of the suspected blood indicator feature in capsule endoscopy according to indication for study. Clin Gastroenterol Hepatol 2008;6:298-301. https://doi.org/10.1016/j.cgh.2007.12.029
  25. D'Halluin PN, Delvaux M, Lapalus MG, et al. Does the "Suspected Blood Indicator" improve the detection of bleeding lesions by capsule endoscopy? Gastrointest Endosc 2005;61:243-249. https://doi.org/10.1016/S0016-5107(04)02587-8
  26. Saurin JC, Lapalus MG, Cholet F, et al. Can we shorten the small-bowel capsule reading time with the "Quick-view" image detection system? Dig Liver Dis 2012;44:477-481. https://doi.org/10.1016/j.dld.2011.12.021
  27. Westerhof J, Koornstra JJ, Weersma RK. Can we reduce capsule endoscopy reading times? Gastrointest Endosc 2009;69:497-502. https://doi.org/10.1016/j.gie.2008.05.070
  28. Halling ML, Nathan T, Kjeldsen J, Jensen MD. High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn's disease. J Gastroenterol Hepatol 2014;29:992-996. https://doi.org/10.1111/jgh.12488
  29. Iakovidis DK, Koulaouzidis A. Software for enhanced video capsule endoscopy: challenges for essential progress. Nat Rev Gastroenterol Hepatol 2015;12:172-186. https://doi.org/10.1038/nrgastro.2015.13
  30. Ting DSW, Cheung CY, Lim G, et al. Development and validation of a deep learning system for diabetic retinopathy and related eye diseases using retinal images from multiethnic populations with diabetes. JAMA 2017;318:2211-2223. https://doi.org/10.1001/jama.2017.18152
  31. Esteva A, Kuprel B, Novoa RA, et al. Dermatologist-level classification of skin cancer with deep neural networks. Nature 2017;542:115-118. https://doi.org/10.1038/nature21056
  32. Iakovidis DK, Koulaouzidis A. Automatic lesion detection in capsule endoscopy based on color saliency: closer to an essential adjunct for reviewing software. Gastrointest Endosc 2014;80:877-883. https://doi.org/10.1016/j.gie.2014.06.026
  33. Karargyris A, Bourbakis N. Detection of small bowel polyps and ulcers in wireless capsule endoscopy videos. IEEE Trans Biomed Eng 2011;58:2777-2786. https://doi.org/10.1109/TBME.2011.2155064
  34. Li B, Meng MQ, Lau JY. Computer-aided small bowel tumor detection for capsule endoscopy. Artif Intell Med 2011;52:11-16. https://doi.org/10.1016/j.artmed.2011.01.003
  35. Li BP, Meng MQ. Comparison of several texture features for tumor detection in CE images. J Med Syst 2012;36:2463-2469. https://doi.org/10.1007/s10916-011-9713-2
  36. Wu X, Chen H, Gan T, Chen J, Ngo CW, Peng Q. Automatic hookworm detection in wireless capsule endoscopy images. IEEE Trans Med Imaging 2016;35:1741-1752. https://doi.org/10.1109/TMI.2016.2527736
  37. Segui S, Drozdzal M, Vilarino F, et al. Categorization and segmentation of intestinal content frames for wireless capsule endoscopy. IEEE Trans Inf Technol Biomed 2012;16:1341-1352. https://doi.org/10.1109/TITB.2012.2221472
  38. Fan Y, Meng MQ, Li B. A novel method for informative frame selection in wireless capsule endoscopy video. Conf Proc IEEE Eng Med Biol Soc 2011;2011:4864-4867.
  39. Rondonotti E, Spada C, Adler S, et al. Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) technical review. Endoscopy 2018;50:423-446. https://doi.org/10.1055/a-0576-0566
  40. Shiotani A, Honda K, Kawakami M, et al. Use of an external real-time image viewer coupled with prespecified actions enhanced the complete examinations for capsule endoscopy. J Gastroenterol Hepatol 2011;26:1270-1274. https://doi.org/10.1111/j.1440-1746.2011.06734.x
  41. Rubin M, Hussain SA, Shalomov A, Cortes RA, Smith MS, Kim SH. Live view video capsule endoscopy enables risk stratification of patients with acute upper GI bleeding in the emergency room: a pilot study. Dig Dis Sci 2011;56:786-791. https://doi.org/10.1007/s10620-010-1336-9
  42. Fischer D, Schreiber R, Levi D, Eliakim R. Capsule endoscopy: the localization system. Gastrointest Endosc Clin N Am 2004;14:25-31. https://doi.org/10.1016/j.giec.2003.10.020
  43. Slawinski PR, Obstein KL, Valdastri P. Capsule endoscopy of the future: what's on the horizon? World J Gastroenterol 2015;21:10528-10541. https://doi.org/10.3748/wjg.v21.i37.10528
  44. Marya N, Karellas A, Foley A, Roychowdhury A, Cave D. Computerized 3-dimensional localization of a video capsule in the abdominal cavity: validation by digital radiography. Gastrointest Endosc 2014;79:669-674. https://doi.org/10.1016/j.gie.2013.11.022
  45. Slawinski PR, Obstein KL, Valdastri P. Emerging issues and future developments in capsule endoscopy. Tech Gastrointest Endosc 2015;17:40-46. https://doi.org/10.1016/j.tgie.2015.02.006
  46. Li X, Chen H, Dai J, Gao Y, Ge Z. Predictive role of capsule endoscopy on the insertion route of double-balloon enteroscopy. Endoscopy 2009;41:762-766. https://doi.org/10.1055/s-0029-1215009
  47. Karargyris A, Koulaouzidis A. OdoCapsule: next-generation wireless capsule endoscopy with accurate lesion localization and video stabilization capabilities. IEEE Trans Biomed Eng 2015;62:352-360. https://doi.org/10.1109/TBME.2014.2352493

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