DOI QR코드

DOI QR Code

연수막 파급을 동반한 뇌실 내 종괴로 나타난 다발골수종의 중추신경계 침범

Central Nervous System Involvement in a Patient with Multiple Myeloma Manifesting as an Intraventricular Mass with Leptomeningeal Spread

  • 이정은 (동국대학교 일산병원 영상의학과) ;
  • 이은자 (동국대학교 일산병원 영상의학과) ;
  • 허희진 (동국대학교 일산병원 진단검사의학과) ;
  • 정재우 (동국대학교 일산병원 진단검사의학과) ;
  • 이은경 (동국대학교 일산병원 영상의학과) ;
  • 이현정 (동국대학교 일산병원 혈액종양내과)
  • Lee, Jung Eun (Department of Radiology, Dongguk University Ilsan Hospital) ;
  • Lee, Eun Ja (Department of Radiology, Dongguk University Ilsan Hospital) ;
  • Huh, Hee Jin (Department of Laboratory Medicine, Dongguk University Ilsan Hospital) ;
  • Chung, Jae-Woo (Department of Laboratory Medicine, Dongguk University Ilsan Hospital) ;
  • Lee, Eun Kyoung (Department of Radiology, Dongguk University Ilsan Hospital) ;
  • Lee, Hyun Jung (Division of Hematology and Medical Oncology, Department of Internal Medicine, Dongguk University Ilsan Hospital)
  • 투고 : 2018.01.07
  • 심사 : 2018.01.27
  • 발행 : 2018.07.01

초록

다발골수종의 중추신경계 침범은 매우 드물다. 경막, 뇌실질 그리고 연수막 침범을 비롯한 다양한 형태의 다발골수종의 중추신경계 침범이 보고 되어 있다. 그중에서 연수막 침범은 흔하지 않게 나타나며 뇌실 내 침범은 극히 드물어 오직 1개의 증례만이 보고 되어 있다. 저자들은 연수막 침범과 신경 주위 파급을 동반한 뇌실 내 종괴로 나타난 다발골수종의 중추신경계 침범 증례를 처음으로 경험하였기에 이를 보고한다. 또한, 뇌실 내 다발골수종의 특징적 전산화 단순촬영과 자기 공명 영상 소견을 기술한다.

Central nervous system involvement in multiple myeloma (CNS-MM) is a rare condition. Various manifestations of CNS-MM have been reported, including dural, parenchymal, and leptomeningeal involvement. Among them, leptomeningeal involvement is less common and intraventricular involvement is exceptional, with only one case reported in the literature. Herein, we report the first case of CNS-MM manifesting as an intraventricular mass with leptomeningeal involvement combined with perineural spread. We also describe characteristic computed tomography and magnetic resonance imaging findings of intraventricular multiple myeloma.

키워드

참고문헌

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