DOI QR코드

DOI QR Code

부갑상선 종양으로 오인된 경부 식도 과립세포종 1례

A case of granular cell tumor of the cervical esophagus misdiagnosed as parathyroid tumor

  • 김동환 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 방성식 (한양대학교 의과대학 병리학교실) ;
  • 신수진 (한양대학교 의과대학 병리학교실) ;
  • 태경 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Kim, Dong Hwan (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Bang, Seong Sik (Department of Pathology, Hanyang University College of Medicine) ;
  • Shin, Su-Jin (Department of Pathology, Hanyang University College of Medicine) ;
  • Tae, Kyung (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine)
  • 투고 : 2018.10.15
  • 심사 : 2018.11.06
  • 발행 : 2018.11.30

초록

Granular cell tumor is an uncommon neoplasm that can occur everywhere in the human body. Granular cell tumor of the cervical esophagus is rare. Histopathologically, granular cell tumor consists of large polygonal cells with small dark nuclei and abundant, fine, granular eosinophilic cytoplasm that show positive immunohistochemical staining using S-100 protein. Surgical excision is the treatment of choice for granular cell tumor. Recurrence is rare, but inadequate resection of granular cell tumor may cause local recurrence. We have experienced one case of granular cell tumor of the cervical esophagus that was misdiagnosed with parathyroid tumor. Therefore, we report it with the literature review.

키워드

참고문헌

  1. Milias S, Hytiroglou P, Kourtis D, Papadimitriou CS. Granular cell tumour of the thyroid gland. Histopathology. 2004;44:190-191. https://doi.org/10.1111/j.1365-2559.2004.01776.x
  2. Cimino-Mathews A, Illei PB, Ali SZ. Atypical granular cell tumor of the thyroid: cytomorphologic features on fine needle aspiration. Diagn Cytopathol. 2011;39:608-611. https://doi.org/10.1002/dc.21509
  3. Cho YH, Ji YB, Song CM, Tae K. A case of thyroid granular cell tumor. Korean J Otorhinolaryngol-Head Neck Surg. 2014;57:108-111. https://doi.org/10.3342/kjorl-hns.2014.57.2.108
  4. Jobrack AD, Goel S, Cotlar AM. Granular Cell Tumor: Report of 13 Cases in a Veterans Administration Hospital. Military medicine. 2018;183:e589-593. https://doi.org/10.1093/milmed/usx237
  5. Song HM, Nam SY, Kim SY, Choi SH. Granular cell tumors of the head and neck: A case report of 9 cases. Korean J Otolaryngol-Head Neck Surg. 2005;48:823-827.
  6. Huang AT, Dominguez LM, Powers CN, Reiter ER. Granular cell tumor of the cervical esophagus: Case report and literature review of an unusual cause of dysphagia. Head and Neck Pathol. 2013;7:274-279. https://doi.org/10.1007/s12105-012-0408-x
  7. Pronesti VM, Goel K, Mitre M. Esophageal granular cell tumor in a 28-year-old: A unique cause for dysphagia. cureus. 2018;10:e2679.
  8. Abrikossoff A. Uber myome, ausgehend von der quergestreiften willkurlichen Muskulatur. Virhows Arch Pathol Anat. 1926;260:215-233. https://doi.org/10.1007/BF02078314
  9. Espinosa-de-Los-Monteros-Franco VA, Martinez-Madrigal F, Ortiz-Hidalgo C. Granular cell tumor (Abrikossoff tumor) of the thyroid gland. Ann Diagn Pathol. 2009;13:269-271. https://doi.org/10.1016/j.anndiagpath.2008.04.008
  10. Fust JA, Custer RP. On the neurogenesis of so-called granular cell myoblastoma. Am J Clin Pathol 1949;19:522-535. https://doi.org/10.1093/ajcp/19.6.522
  11. Fisher ER, Wechsler H. Granular cell myoblastoma--a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma). Cancer. 1962;15:936-954. https://doi.org/10.1002/1097-0142(196209/10)15:5<936::AID-CNCR2820150509>3.0.CO;2-F
  12. Min KW, Paik SS, Jun YJ, Han H, Jang KS. Fine needle aspiration cytology of a granular cell tumor arising in the thyroid gland. Cytopathology. 2012;23:411-412. https://doi.org/10.1111/j.1365-2303.2011.00920.x
  13. Goldblum JR, Rice TW, Zuccaro G, Richter JE. Granular cell tumors of the esophagus: A clinical and pathologic study of 13 cases. Ann Thor Surg. 1996;62:860-865. https://doi.org/10.1016/S0003-4975(96)00443-2
  14. Liu J, Krishnamouthy S. The importance of fine needle aspiration in conjunction with radiologic examination in the evaluation of granular cell tumor presenting as a thyroid mass: A case report. Int J Clin Exp Pathol. 2011;4:197-199.
  15. John BK, Dang NC, Hussain SA, Yang GC, Cham MD, Yantiss R et al. Multifocal granular cell tumor presenting as an esophageal stricture. J Gastrointest Cancer. 2008;39:107-113. https://doi.org/10.1007/s12029-009-9056-0