Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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The diagnostic value of i-scan image-enhanced endoscopy in the diagnosis of oral cavity leukoplakia

구강 백반증 진단에 있어서 i-scan image-enhanced 내시경의 진단적 유용성

  • Lee, Young Chan (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University) ;
  • Eun, Young-Gyu (Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University) ;
  • Park, Il-Seok (Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Dongtan Sacred Heart Hospital)
  • 이영찬 (경희대학교 이비인후과학교실) ;
  • 은영규 (경희대학교 이비인후과학교실) ;
  • 박일석 (한림대학교 동탄성심병원 이비인후과학교실)
  • Received : 2018.11.02
  • Accepted : 2018.11.07
  • Published : 2018.11.30
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Abstract

Background/Objectives: The aim of this study was to investigate the diagnostic value of i-scan in the differential diagnosis of oral cavity leukoplakia based on visualization of abnormal vascular features. Materials & Methods: Thirty- one patients with oral cavity leukoplakia were enrolled in the study. Images of their oral cavity obtained using conventional white light endoscopy and an i-scan-enhanced endoscopy (Pentax DEFINA EPK-3000 Video Processors, with Pentax VNLJ10) were reviewed. The microvascular features of the lesions and vascular changes were analyzed and the results were compared with the histopathologic diagnosis. Results: Among the 31 oral cavity leukoplakia patients, 8 (25.8%) patients revealed hyperkeratosis, 10 (31.2%) low-grade dysplasia, 5 (16.2%) high-grade dysplasia and 8 (25.8%) invasive squamous cell carcinoma on histopathologic examination. Using i-scan-enhanced endoscopy, we could found abnormal vascular change with neoplastic neoangiogenesis in most high-grade dysplasia or invasive cancer in oral cavity. (high-grade dysplasia: 4/5 [80.0%], and invasive squamous cell carcinoma: 7/8 [87.5%]). Conclusion: i-scan-enhanced endoscopy could be a useful optical technique for the diagnosis of oral cavity leukoplakia. Our results suggest that i-scan may be a promising diagnostic tool in the early detection of suspected oral mucosal lesion.

Keywords

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