한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제35권2호
  • /
  • Pages.53-56
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  • 2018
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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Imaging Features of Hepatic Adenoma in a Dog with Atypical Computed Tomographic Findings

  • Jin, Hansol (College of Veterinary Medicine, Chonnam National University) ;
  • Cheon, Byunggyu (College of Veterinary Medicine, Chonnam National University) ;
  • Lee, Gahyun (College of Veterinary Medicine, Chonnam National University) ;
  • Park, Seungjo (College of Veterinary Medicine, Chonnam National University) ;
  • Lee, Ju-Hwan (Chonnam National University Veterinary Teaching Hospital) ;
  • Choi, Jihye (College of Veterinary Medicine, Chonnam National University)
  • 투고 : 2017.08.09
  • 심사 : 2018.02.27
  • 발행 : 2018.04.30
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초록

Computed tomography (CT) findings of hepatic adenoma in veterinary medicine are variable and unlike in human medicine, not defined clearly. A 12-year-old neutered male Shih Tzu presented after a seizure, with weight loss, salivation, and cachexia. An abdominal mass was identified on radiography, and ultrasonographic images showed a mixed echo pattern with marked vascularity. CT showed that the mass originated from caudate lobe, was heterogeneously hypoattenuated compared with the hepatic parenchyma, and had irregular margins. Contrast enhanced CT showed that the mass enhanced like the surrounding liver parenchyma. However, it contained unenhanced areas and enhanced vessels were observed in the arterial phase at the periphery of the mass. The margins of mass were more enhanced in the venous phase than the arterial phase and the hypoattenuating regions within the mass were not enhanced. Greater enhancing in the venous phase is seen with adenomas; however, the heterogeneous enhancement pattern, especially the marginal vascular enhancement and internal hypoattenuating regions, is seen with malignancy. Although this is a single case of hepatic adenoma, the atypical enhanced pattern of this case can provide useful information to predict the malignancy of primary liver tumor.

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참고문헌

  1. Barr F. Percutaneous biopsy of abdominal organs under ultrasound guidance. J Small Anim Pract 1995; 36: 105-113. https://doi.org/10.1111/j.1748-5827.1995.tb02843.x
  2. Bartolozzi C, Lencioni R, Paolicchi A, Moretti M, Armillotta N, Pinto F. Differentiation of hepatocellular adenoma and focal nodular hyperplasia of the liver: comparison of power Doppler imaging and conventional color Doppler sonography. Eur Radiol 1997; 7: 1410-1415. https://doi.org/10.1007/s003300050308
  3. Bates SM, Keller MS, Ramos IM, Carter D, Taylor K. Hepatoblastoma: detection of tumor vascularity with duplex Doppler US. Radiology 1990; 176: 505-507. https://doi.org/10.1148/radiology.176.2.2164236
  4. Evans SM. The radiographic appearance of primary liver neoplasia in dogs. Vet Radiol Ultrasound 1987; 28: 192-196. https://doi.org/10.1111/j.1740-8261.1987.tb00051.x
  5. Eves NG. Hepatocellular adenoma in a 12-year-old crossbred German shepherd dog. Can Vet J 2004; 45: 326-328.
  6. Faverzani S, Chinosi S, Valenti P, Caniatti M. Comparison between ultrasonography and cytology of liver focal lesions and parenchyma in the dog and cat. Vet Res Commun 2006; 30: 293-296.
  7. Feeney D, Johnston G, Hardy R. Two-dimensional, gray-scale ultrasonography for assessment of hepatic and splenic neoplasia in the dog and cat. J Am Vet Med Assoc 1984; 184: 68-81.
  8. Fong Y, Kemeny N, Lawrence T. Cancer of the liver and biliary tree. In: De Vita VT, Hellman S, Rosenberg S, eds. Cancer: principles and practice of oncology. Philadelphia, USA: Lippincott Williams and Wilkins, 2001: 1178-1203.
  9. Fukushima K, Kanemoto H, Ohno K, Takahashi M, Nakashima K, Fujino Y, et al. CT characteristics of primary hepatic mass lesions in dogs. Vet Radiol Ultrasound 2012; 53: 252-257.
  10. Grazioli L, Federle MP, Brancatelli G, Ichikawa T, Olivetti L, Blachar A. Hepatic adenomas: Imaging and pathologic findings 1. Radiographics 2001; 21: 877-892. https://doi.org/10.1148/radiographics.21.4.g01jl04877
  11. Guillot M, D'Anjou MA, Alexander K, BEDard C, Desnoyers M, Beauregard G, et al. Can sonographic findings predict the results of liver aspirates in dogs with suspected liver disease? Vet Radiol Ultrasound 2009; 50: 513-518. https://doi.org/10.1111/j.1740-8261.2009.01572.x
  12. Hammer AS, Sikkema DA. Hepatic neoplasia in the dog and cat. Vet Clin North Am Small Anim Pract 1995; 25: 419-435. https://doi.org/10.1016/S0195-5616(95)50035-X
  13. Koito K, Namieno T, Morita K. Differential diagnosis of small hepatocellular carcinoma and adenomatous hyperplasia with power Doppler sonography. Am J Roentgenol 1998; 170: 157-161. https://doi.org/10.2214/ajr.170.1.9423624
  14. Lawrence HJ, Erb HN, Harvey H. Nonlymphomatous hepatobiliary masses in cats: 41 cases (1972 to 1991). Vet Surg 1994; 22: 365-368.
  15. Leveille R, Partington BP, Biller D, Miyabayashi T. Complications after ultrasound-guided biopsy of abdominal structures in dogs and cats: 246 cases (1984-1991). J Am Vet Med Assoc 1993; 203: 413-415.
  16. Liptak JM, Dernell WS, Monnet E, Powers BE, Bachand AM, Kenney JG, et al. Massive hepatocellular carcinoma in dogs: 48 cases (1992-2002). J Am Vet Med Assoc 2004; 225: 1225-1230. https://doi.org/10.2460/javma.2004.225.1225
  17. Liptak JM, MVetClinStud F, Dernell WS, Withrow SJ. Liver tumors in cats and dogs. Compend Contin Educ Pract Vet 2004; 36: 50-56.
  18. Newell S, Selcer B, Girard E, Roberts G, Thompson JP, Harrison J. Correlations between ultrasonographic findings and specific hepatic diseases in cats: 72 cases (1985-1997). J Am Vet Med Assoc 1998; 213: 94-98.
  19. Orr NM, Taylor KJ. Doppler detection of tumor vascularity. Clin Diagn Ultrasound 1990; 26: 149-163.
  20. Patnaik A, Hurvitz A, Lieberman P, Johnson G. Canine hepatocellular carcinoma. Vet. Pathol 1981; 18: 427-438. https://doi.org/10.1177/030098588101800402
  21. Post G, Patnaik A. Nonhematopoietic hepatic neoplasms in cats: 21 cases (1983-1988). J Am Vet Med Assoc 1992; 201: 1080-1082.
  22. Taylor K, Ramos I, Carter D, Morse S, Snower D, Fortune K. Correlation of Doppler US tumor signals with neovascular morphologic features. Radiology 1988; 166: 57-62. https://doi.org/10.1148/radiology.166.1.2447604
  23. Voros K, Vrabely T, Papp L, Horvath L, Karsai F. Correlation of ultrasonographic and patho morphological findings in canine hepatic diseases. J Small Anim Pract 1991; 32: 627-634. https://doi.org/10.1111/j.1748-5827.1991.tb00907.x
  24. Whiteley M, Feeney D, Whiteley L, Hardy R. Ultrasonographic appearance of primary and metastatic canine hepatic tumors. A review of 48 cases. J Ultrasound Med 1989; 8: 621-630. https://doi.org/10.7863/jum.1989.8.11.621