대한치매학회지 (Dementia and Neurocognitive Disorders)

대한치매학회 (Korean Dementia Association)
권호 표지
DOI QR코드

DOI QR Code

Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient

  • Kim, Yong Sung (Department of Neurology, College of Medicine, Hanyang University) ;
  • Kim, Seung Jae (Department of Neurology, College of Medicine, Hanyang University) ;
  • Lee, Jongmin (Department of Neurology, College of Medicine, Hanyang University) ;
  • Kim, Hee-Jin (Department of Neurology, College of Medicine, Hanyang University)
  • 투고 : 2018.01.04
  • 심사 : 2018.02.15
  • 발행 : 2018.03.31
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia. Case Report: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy. Conclusions: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.

키워드

참고문헌

  1. Manto M, Bower JM, Conforto AB, Delgado-Garcia JM, da Guarda SN, Gerwig M, et al. Consensus paper: roles of the cerebellum in motor control--the diversity of ideas on cerebellar involvement in movement. Cerebellum 2012;11:457-487. https://doi.org/10.1007/s12311-011-0331-9
  2. Marien P, Ackermann H, Adamaszek M, Barwood CH, Beaton A, Desmond J, et al. Consensus paper: language and the cerebellum: an ongoing enigma. Cerebellum 2014;13:386-410.
  3. Stefanova N, Bucke P, Duerr S, Wenning GK. Multiple system atrophy: an update. Lancet Neurol 2009;8:1172-1178. https://doi.org/10.1016/S1474-4422(09)70288-1
  4. Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998;51:1546-1554. https://doi.org/10.1212/WNL.51.6.1546
  5. Chang CC, Chang YY, Chang WN, Lee YC, Wang YL, Lui CC, et al. Cognitive deficits in multiple system atrophy correlate with frontal atrophy and disease duration. Eur J Neurol 2009;16:1144-1150. https://doi.org/10.1111/j.1468-1331.2009.02661.x
  6. Siri C, Duerr S, Canesi M, Delazer M, Esselink R, Bloem BR, et al. A cross-sectional multicenter study of cognitive and behavioural features in multiple system atrophy patients of the parkinsonian and cerebellar type. J Neural Transm (Vienna) 2013;120:613-618. https://doi.org/10.1007/s00702-013-0997-x
  7. Riecker A, Mathiak K, Wildgruber D, Erb M, Hertrich I, Grodd W, et al. fMRI reveals two distinct cerebral networks subserving speech motor control. Neurology 2005;64:700-706. https://doi.org/10.1212/01.WNL.0000152156.90779.89
  8. Jurgens U. Neural pathways underlying vocal control. Neurosci Biobehav Rev 2002;26:235-258. https://doi.org/10.1016/S0149-7634(01)00068-9
  9. Brady JP. Drug-induced stuttering: a review of the literature. J Clin Psychopharmacol 1998;18:50-54. https://doi.org/10.1097/00004714-199802000-00008
  10. Gaile S, Noviasky JA. Speech disturbance and marked decrease in function seen in several older patients on olanzapine. J Am Geriatr Soc 1998;46:1330-1331. https://doi.org/10.1111/j.1532-5415.1998.tb04565.x
  11. Granger AS, Hanger HC. Olanzapine: extrapyramidal side effects in the elderly. Aust N Z J Med 1999;29:371-372. https://doi.org/10.1111/j.1445-5994.1999.tb00722.x
  12. Armstrong RA. Visual signs and symptoms of multiple system atrophy. Clin Exp Optom 2014;97:483-491. https://doi.org/10.1111/cxo.12206
  13. Gustaw K, Gonet W. Speech disorders in multiple system atrophy of parkinson type. Clin Res 2007;1:185-188.

피인용 문헌

  1. Elucidating the Risk Factors for Progression from Amyloid-Negative Amnestic Mild Cognitive Impairment to Dementia vol.17, pp.10, 2018, https://doi.org/10.2174/1567205017666201130094259