Dementia and Neurocognitive Disorders (대한치매학회지)

Korean Dementia Association (대한치매학회)
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Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient

  • Kim, Yong Sung (Department of Neurology, College of Medicine, Hanyang University) ;
  • Kim, Seung Jae (Department of Neurology, College of Medicine, Hanyang University) ;
  • Lee, Jongmin (Department of Neurology, College of Medicine, Hanyang University) ;
  • Kim, Hee-Jin (Department of Neurology, College of Medicine, Hanyang University)
  • Received : 2018.01.04
  • Accepted : 2018.02.15
  • Published : 2018.03.31
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Abstract

Background: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia. Case Report: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy. Conclusions: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.

Keywords

References

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