참고문헌
- Scatena R (2012) Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation. Adv Exp Med Biol 942, 287-308
- Um JH and Yun J (2017) Emerging role of mitophagy in human diseases and physiology. BMB Rep 50, 299-307 https://doi.org/10.5483/BMBRep.2017.50.6.056
- Cho B and Sun W (2017) CoMIC, the hidden dynamics of mitochondrial inner compartments. BMB Rep 50, 597-598 https://doi.org/10.5483/BMBRep.2017.50.12.154
- Taanman JW (1999) The mitochondrial genome: structure, transcription, translation and replication. Biochim Biophys Acta 1410, 103-123 https://doi.org/10.1016/S0005-2728(98)00161-3
- Brandon M, Baldi P and Wallace DC (2006) Mitochondrial mutations in cancer. Oncogene 25, 4647-4662 https://doi.org/10.1038/sj.onc.1209607
- Chatterjee A, Mambo E and Sidransky D (2006) Mitochondrial DNA mutations in human cancer. Oncogene 25, 4663-4674 https://doi.org/10.1038/sj.onc.1209604
- Chen EI (2012) Mitochondrial dysfunction and cancer metastasis. J Bioenerg Biomembr 44, 619-622 https://doi.org/10.1007/s10863-012-9465-9
- Boland ML, Chourasia AH and Macleod KF (2013) Mitochondrial dysfunction in cancer. Front Oncol 3, 292
- Kim N, Min WK, Park MH, Lee JK, Jin HK and Bae JS (2016) Neuropeptide Y protects kidney against cisplatininduced nephrotoxicity by regulating p53-dependent apoptosis pathway. BMB Rep 49, 288-292 https://doi.org/10.5483/BMBRep.2016.49.5.231
- Brosh R and Rotter V (2009) When mutants gain new powers: news from the mutant p53 field. Nat Rev 9, 701-713 https://doi.org/10.1038/nrc2693
- Koczor CA, White RC, Zhao P et al (2012) p53 and mitochondrial DNA: their role in mitochondrial homeostasis and toxicity of antiretrovirals. Am J Pathol 180, 2276-2283 https://doi.org/10.1016/j.ajpath.2012.01.045
- Bourdon A, Minai L, Serre V et al (2007) Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nat Genet 39, 776-780 https://doi.org/10.1038/ng2040
- Charlot JF, Pretet JL, Haughey C and Mougin C (2004) Mitochondrial translocation of p53 and mitochondrial membrane potential (Delta Psi m) dissipation are early events in staurosporine-induced apoptosis of wild type and mutated p53 epithelial cells. Apoptosis 9, 333-343 https://doi.org/10.1023/B:APPT.0000025810.58981.4c
- Wang W, Sun Q, Wu Z et al (2013) Mitochondrial dysfunction-related genes in hepatocellular carcinoma. Front Biosci (Landmark edition) 18, 1141-1149 https://doi.org/10.2741/4169
- Bode AM and Dong Z (2004) Post-translational modification of p53 in tumorigenesis. Nat Rev 4, 793-805 https://doi.org/10.1038/nrc1455
- Galluzzi L, Morselli E, Kepp O et al (2008) Targeting p53 to mitochondria for cancer therapy. Cell Cycle 7, 1949-1955 https://doi.org/10.4161/cc.7.13.6222
- Miceli MV and Jazwinski SM (2005) Common and cell type-specific responses of human cells to mitochondrial dysfunction. Exp Cell Res 302, 270-280 https://doi.org/10.1016/j.yexcr.2004.09.006
- Mansfield KD, Guzy RD, Pan Y et al (2005) Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell Metab 1, 393-399 https://doi.org/10.1016/j.cmet.2005.05.003
- Kemp CJ, Donehower LA, Bradley A and Balmain A (1993) Reduction of p53 gene dosage does not increase initiation of promotion but enhances malignant progression of chemically induced skin tumors. Cell 74, 813-822 https://doi.org/10.1016/0092-8674(93)90461-X
- Zhu Y, Guignard F, Zhao D et al (2005) Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 8, 119-130 https://doi.org/10.1016/j.ccr.2005.07.004
- Butow RA and Avadhani NG (2004) Mitochondrial signaling: the retrograde response. Mol Cell 14, 1-15 https://doi.org/10.1016/S1097-2765(04)00179-0
- Pelicano H, Xu RH, Du M et al (2006) Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol 175, 913-923 https://doi.org/10.1083/jcb.200512100
- Tergaonkar V, Pando M, Vafa O et al (2002) p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy. Cancer Cell 1, 493-503 https://doi.org/10.1016/S1535-6108(02)00068-5
- Huang WC, Ju TK, Hung MC and Chen CC (2007) Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. Mol cell 26, 75-87 https://doi.org/10.1016/j.molcel.2007.02.019
- Ferran C, Millan MT, Csizmadia V et al (1995) Inhibition of NF-kappa B by pyrrolidine dithiocarbamate blocks endothelial cell activation. Biochem Biophys Res Commun 241, 212-223
- Wallace DC (2012) Mitochondria and cancer. Nature Rev 12, 685-698
- Ishikawa K, Takenaga K, Akimoto M et al (2008) ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis. Science NY 320, 661-664 https://doi.org/10.1126/science.1156906
- Kulawiec M, Owens KM and Singh KK (2009) Cancer cell mitochondria confer apoptosis resistance and promote metastasis. Cancer Biol Ther 8, 1378-1385
- Vaux EC, Metzen E, Yeates KM and Ratcliffe PJ (2001) Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 98, 296-302 https://doi.org/10.1182/blood.V98.2.296
- Naito A, Cook CC, Mizumachi T et al (2008) Progressive tumor features accompany epithelial-mesenchymal transition induced in mitochondrial DNA-depleted cells. Cancer Sci 99, 1584-1588 https://doi.org/10.1111/j.1349-7006.2008.00879.x
- Ishikawa F, Kaneko E, Sugimoto T et al (2014) A mitochondrial thioredoxin-sensitive mechanism regulates TGF-beta-mediated gene expression associated with epithelial-mesenchymal transition. Biochem Biophys Res Commun 443, 821-827 https://doi.org/10.1016/j.bbrc.2013.12.050
- Efeyan A and Serrano M (2007) p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 6, 1006-1010 https://doi.org/10.4161/cc.6.9.4211
- Kulawiec M, Ayyasamy V and Singh KK (2009) p53 regulates mtDNA copy number and mitocheckpoint pathway. J Carcinogenesis 8, 8 https://doi.org/10.4103/1477-3163.50893
- Chen D, Yu Z, Zhu Z and Lopez CD (2006) The p53 pathway promotes efficient mitochondrial DNA base excision repair in colorectal cancer cells. Cancer Res 66, 3485-3494 https://doi.org/10.1158/0008-5472.CAN-05-4103