DOI QR코드

DOI QR Code

Relationship between Nutrition Intake and Estimated Glomerular Filtration Rate in Korean Adults (30-65 years) from the Korea National Health and Nutrition Examination Survey 2013-2014

  • Ryu, Jihye (Department of Food Science and Nutrition, Brain Busan 21 Project, Dong-A University) ;
  • Yoon, So Ra (Department of Food Science and Nutrition, Brain Busan 21 Project, Dong-A University) ;
  • An, Won Suk (Department of Internal Medicine, Dong-A University College of Medicine) ;
  • Kim, Oh Yoen (Department of Food Science and Nutrition, Brain Busan 21 Project, Dong-A University)
  • 투고 : 2018.03.17
  • 심사 : 2018.04.09
  • 발행 : 2018.04.30

초록

This study aimed to examine the relationship between nutrition intake and estimated glomerular filtration rate (eGFR) indicating kidney function in Korean individuals without diabetes or cardiovascular disease. Study participants from the Korea National Health and Nutrition Examination Survey 2013-2014 (n = 4,378, 30-65 years) were classified by their eGFR levels ($mL/min/1.732m^2$): ${\geq}120$ (n = 299), 119-105 (n = 789), 104-90 (n = 1,578), 89-60 (n = 1,685), < 60 (n = 27). After adjusted for confounding factors (age, sex, cigarette smoking, alcohol drinking, total caloric intake [TCI], income status, education level, body mass index, and physical activity), blood pressure, low-density lipoprotein (LDL) cholesterol, aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen, creatinine, fasting glucose, and glycated hemoglobin were higher, and high density lipoprotein cholesterol levels were lower in participants with lower eGFR levels than those with higher eGFR levels. n-3 fatty acid (FA) and n-6 FA (% of TCI/day) intake were also significantly higher in participants with higher eGFR levels than in those with lower eGFR levels. Based on the above results, participants were subdivided into 3 groups according to n-6 FA intake levels (Q1: ${\geq}2.93%$, n = 1,462; Q2: 2.92%-1.88%, n = 1,463; Q3: < 1.88%, n = 1,453). People consuming higher n-6 FAs, particularly the Q1 group showed higher eGFR levels and lower levels of LDL cholesterol and creatinine. In conclusion, higher intake of n-6 FAs within the range of dietary reference may be beneficial to maintain healthy kidney function.

키워드

과제정보

연구 과제 주관 기관 : National Research Foundation of Korea

참고문헌

  1. Health Insurance Review & Assessment Service (KR). Healthcare Bigdata Hub. Medical information statistics [Internet]. Available from http://opendata.hira.or.kr/op/opc/olapMfrnIntrsIlnsInfo.do [cited 2016 May 25]. 2016.
  2. Organisation for Economic Cooperation and Development. OECD health data statistics [Internet]. Available from https://doi.org/10.1787/data-00542-en [cited 2018 April 16]. 2010.
  3. Kim TH. Study on the socioeconomic burden of chronic kidney disease. Cheongwon: Korea Centers for Disease Control and Prevention; 2012.
  4. Lee SJ, Chung CW. Health behaviors and risk factors associated with chronic kidney disease in Korean patients with diabetes: the Fourth Korean National Health and Nutritional Examination Survey. Asian Nurs Res 2014;8:8-14. https://doi.org/10.1016/j.anr.2013.11.001
  5. Lee SW, Kim YC, Oh SW, Koo HS, Na KY, Chae DW, Kim S, Chin HJ. Trends in the prevalence of chronic kidney disease, other chronic diseases and health-related behaviors in an adult Korean population: data from the Korean National Health and Nutrition Examination Survey (KNHANES). Nephrol Dial Transplant 2011;26:3975-80. https://doi.org/10.1093/ndt/gfr154
  6. Park JI, Baek H, Jung HH. CKD and health-related quality of life: the Korea National Health and Nutrition Examination Survey. Am J Kidney Dis 2016;67:851-60. https://doi.org/10.1053/j.ajkd.2015.11.005
  7. Thijssen S, Kitzler TM, Levin LW. Salt: its role in chronic kidney disease. J Ren Nutr 2008;18:18-26. https://doi.org/10.1053/j.jrn.2007.10.006
  8. McMahon EJ, Campbell KL, Bauer JD. Taste perception in kidney disease and relationship to dietary sodium intake. Appetite 2014;83:236-41. https://doi.org/10.1016/j.appet.2014.08.036
  9. Sanders PW. Effect of salt intake on progression of chronic kidney disease. Curr Opin Nephrol Hypertens 2006;15:54-60. https://doi.org/10.1097/01.mnh.0000186853.23512.a5
  10. Higashiyama A, Watanabe M, Kokubo Y, Ono Y, Okayama A, Okamura TNIPPON DATA80/90 Research Group. Relationships between protein intake and renal function in a Japanese general population: NIPPON DATA90. J Epidemiol 2010;20:S537-43. https://doi.org/10.2188/jea.JE20090222
  11. Shah BV. The changing role of dietary protein restriction in management of Chronic Kidney Disease (CKD). J Assoc Physicians India 2015;63:34-40.
  12. Kim OY, Kwak SY, Kim B, Kim YS, Kim HY, Shin MJ. Selected food consumption mediates the association between education level and metabolic syndrome in Korean adults. Ann Nutr Metab 2017;70:122-31. https://doi.org/10.1159/000470853
  13. Park HS, Park CY, Oh SW, Yoo HJ. Prevalence of obesity and metabolic syndrome in Korean adults. Obes Rev 2008;9:104-7.
  14. Kim MK, Lee WY, Kang JH, Kang JH, Kim BT, Kim SM, Kim EM, Suh SH, Shin HJ, Lee KR, Lee KY, Lee SY, Lee SY, Lee SK, Lee CB, Chung S, Jeong IK, Hur KY, Kim SS, Woo JTCommittee of Clinical Practice Guidelines; Korean Society for the Study of Obesity. 2014 clinical practice guidelines for overweight and obesity in Korea. Endocrinol Metab 2014;29:405-9. https://doi.org/10.3803/EnM.2014.29.4.405
  15. Wiebe N, Klarenbach SW, Allan GM, Manns BJ, Pelletier R, James MT, Bello A, Hemmelgarn BR, Tonelli MAlberta Kidney Disease Network. Potentially preventable hospitalization as a complication of CKD: a cohort study. Am J Kidney Dis 2014;64:230-8. https://doi.org/10.1053/j.ajkd.2014.03.012
  16. Smyth A, Griffin M, Yusuf S, Mann JF, Reddan D, Canavan M, Newell J, O'Donnell M. Diet and major renal outcomes: a prospective cohort study. The NIH-AARP Diet and Health Study. J Ren Nutr 2016;26:288-98. https://doi.org/10.1053/j.jrn.2016.01.016
  17. Mekki K, Remaoun M, Belleville J, Bouchenak M. Hemodialysis duration impairs food intake and nutritional parameters in chronic kidney disease patients. Int Urol Nephrol 2012;44:237-44. https://doi.org/10.1007/s11255-010-9875-8
  18. Khatri M, Moon YP, Scarmeas N, Cu Y, Gardener H, Cheung K, Wright CB, Sacco RL, Nickolas TL, Elkind MS. The association between a mediterranean-style diet and kidney function in the Northern Manhattan Study Cohort. Clin J Am Soc Nephrol 2014;9:1868-75. https://doi.org/10.2215/CJN.01080114
  19. Chung HF, Lomg KZ, Hsu CC, Al Mamun A, Jhang HR, Shin SJ, Hwang SJ, Huang MC. Association of n-3 polyunsaturated fatty acids and inflammatory indicators with renal function decline in type 2 diabetes. Clin Nutr 2015;34:229-34. https://doi.org/10.1016/j.clnu.2014.02.009
  20. Eide IA, Jenssen T, Hartmann A, Diep LM, Dahle DO, Reisaeter AV, Bjerve KS, Christensen JH, Schmidt EB, Svensson M. The association between marine n-3 polyunsaturated fatty acid levels and survival after renal transplantation. Clin J Am Soc Nephrol 2015;10:1246-56. https://doi.org/10.2215/CJN.11931214
  21. Malhotra R, Cavanaugh KL, Blot WJ, Lkizler TA, Lipworth L, Kabagambe EK. Dietary polyunsaturated fatty acids and incidence of end-stage renal disease in the Southern Community Cohort Study. BMC Nephrol 2016;17:152. https://doi.org/10.1186/s12882-016-0371-y
  22. Bjermo H, Iggman D, Kullberg J, Dahlman I, Johansson L, Persson L, Berglund J, Pulkki K, Basu S, Uusitupa M, Rudling M, Arner P, Cederholm T, Ahlstrom H, Riserus U. Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial. Am J Clin Nutr 2012;95:1003-12. https://doi.org/10.3945/ajcn.111.030114
  23. Ministry of Health and Welfare (KR); The Korean Nutrition Society. Dietary reference intakes for Koreans 2015. Sejong: Ministry of Health and Welfare; 2016.
  24. Yuzbashian E, Asghari G, Mirmiran P, Hosseini FS, Azizi F. Associations of dietary macronutrients with glomerular filtration rate and kidney dysfunction: Tehran lipid and glucose study. J Nephrol 2015;28:173-80. https://doi.org/10.1007/s40620-014-0095-7
  25. Liu HQ, Qiu Y, Mu Y, Zhang XJ, Liu L, Hou XH, Zhang L, Xu XN, Ji AL, Cao R, Yang RH, Wang F. A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD rats. Nutr Res 2013;33:849-58. https://doi.org/10.1016/j.nutres.2013.07.004
  26. Chung HF, Long KZ, Hsu CC, AlMamun A, Jhang HR, Shin SJ, Hwang SJ, Huang MC. Association of n-3 polyunsaturated fatty acids and inflammatory indicators with renal function decline in type 2 diabetes. Clin Nutr 2015;34:229-34. https://doi.org/10.1016/j.clnu.2014.02.009
  27. Yang LG, Song ZX, Yin H, Wang YY, Shu GF, Lu HX, Wang SK, Sun GJ. Low n-6/n-3 PUFA ratio improves lipid metabolism, inflammation, oxidative stress and endothelial function in rats using plant oils as n-3 fatty acid source. Lipids 2016;51:49-59. https://doi.org/10.1007/s11745-015-4091-z