Clinical Nutrition Research

The Korean Society of Clinical Nutrition (한국임상영양학회)
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Dietary Intake of Thiamine in Migraine Patients and Healthy Subjects: a Case-Control Study

  • Faraji, Hossein (Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences) ;
  • Paknahad, Zamzam (Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences) ;
  • Chitsaz, Ahmad (Department of Neurology, Isfahan University of Medical Sciences)
  • Received : 2017.12.26
  • Accepted : 2018.01.20
  • Published : 2018.01.31
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Abstract

The migraine headache is a disease related to the neurovascular system, which affects 10%-20% of people, worldwide. Recent evidences suggested a relation between thiamine status and migraine headaches. The current study was undertaken to assess dietary intake of the thiamine in migraine patients and to evaluate its association with the frequency of migraine attacks. In a case-control design, the current study was performed on 50 migraine patients and 50 healthy people, 20-60 years old in Isfahan, Iran, in 2017. Information about dietary intake was collected by Food frequency questionnaire and analyzed using the Nutritionist version 4 (N4) software (Tinuviel Software). Information about the history of disease was collected by demographic questionnaire. Analysis of covariance and independent t-test were used for data analysis and p value less than 0.05 was considered significant. Mean age, weight, height, and body mass index of participants were $35.1{\pm}9.8years$, $65.3{\pm}10.4kg$, $162.5{\pm}8.4cm$, and $24.7{\pm}4.0kg/m^2$, respectively. Dietary intake of thiamine among the migraine patients was lower than that in the healthy participants (p < 0.001). Migraine patients with the high frequency attacks had significantly lower intake of thiamine compared with moderate frequency attacks group (p = 0.010), however, it was not significant after adjusting for energy intake (p = 0.410, p = 0.240). Dietary intake of thiamine in migraine patients was not significantly different in comparing with healthy subjects. In addition, no significant correlation between thiamine intake and the frequency of migraine attacks was observed.

Keywords

Acknowledgement

Supported by : Isfahan University of Medical Sciences

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