Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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Ultrasonographic and Pathologic Findings of Dermatofibrosarcoma Protuberans of the Breast: A Case Report

유방에 생긴 융기성 피부섬유육종의 초음파 및 병리 소견: 증례 보고

  • Noh, Jung Hyun (Department of Radiology, Dankook University Hospital, Dankook University College of Medicine) ;
  • Min, Jun Won (Department of Surgery, Dankook University Hospital, Dankook University College of Medicine) ;
  • Myung, Na Hye (Department of Pathology, Dankook University Hospital, Dankook University College of Medicine) ;
  • Kim, You Me (Department of Radiology, Dankook University Hospital, Dankook University College of Medicine)
  • 노정현 (단국대학교 의과대학 단국대학교병원 영상의학과) ;
  • 민준원 (단국대학교 의과대학 단국대학교병원 외과) ;
  • 명나혜 (단국대학교 의과대학 단국대학교병원 병리과) ;
  • 김유미 (단국대학교 의과대학 단국대학교병원 영상의학과)
  • Received : 2017.07.22
  • Accepted : 2017.12.07
  • Published : 2018.05.01
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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare, malignant soft tissue tumor. It arises from the dermis, however, a few lesions are known to infiltrate into deeper layers. It commonly occurs on the trunk and extremities, but rarely involves the breast. We report a case of a 43-year-old woman who had histologically proven DFSP of the breast, with emphasis on ultrasonographic findings and pathological features. In our case, the ultrasonographic features of DFSP revealed an ovalshaped hypoechoic mass in the dermis of left breast with surrounded by increased levels of echogenic subcutaneous fat. This ultrasonographic finding correlated with pathologic features of infiltration of tumor cells into the subcutaneous fat. No previous study reported this feature of DFSP associated with the breast.

융기성 피부섬유육종은 드문 악성 연부조직 종양이다. 진피층에서 발생하며, 일부 병변은 더 깊은 층으로 침윤하기도 한다. 이 종양은 주로 체간이나 사지에서 호발하며, 유방에서는 드물게 발생한다. 우리는 43세 여성의 유방에서 발생한 융기성 피부섬유육종에 대해서 초음파 소견과 병리 소견에 중점을 두어 증례 보고를 하고자 한다. 초음파에서는 진피층에 난원형의 저에코의 종괴로 보이고 주변의 피하지방의 에코 증가소견이 관찰되었다. 이러한 초음파 소견은 종양세포가 피하지방으로 침윤하는 병리학적 소견과 일치하였으며, 유방에 생긴 융기성 피부섬유육종에서 이러한 소견은 아직까지 보고된 바 없었다.

Keywords

References

  1. Taylor HB, Helwig EB. Dermatofibrosarcoma protuberans: a study of 115 cases. Cancer 1962;15:717-725 https://doi.org/10.1002/1097-0142(196207/08)15:4<717::AID-CNCR2820150405>3.0.CO;2-2
  2. Mendenhall WM, Zlotecki RA, Scarborough MT. Dermatofibrosarcoma protuberans. Cancer 2004;101:2503-2508 https://doi.org/10.1002/cncr.20678
  3. Chuang TY, Su WP, Muller SA. Incidence of cutaneous T cell lymphoma and other rare skin cancers in a defined population. J Am Acad Dermatol 1990;23:254-256 https://doi.org/10.1016/0190-9622(90)70208-Y
  4. Gloster HM Jr. Dermatofibrosarcoma protuberans. J Am Acad Dermatol 1996;35:355-374; quiz 375-376 https://doi.org/10.1016/S0190-9622(96)90597-6
  5. Fukushima H, Suda K, Matsuda M, Tanaka R, Kita H, Hanaoka T, et al. A case of dermatofibrosarcoma protuberans in the skin over the breast of a young woman. Breast Cancer 1998; 5:407-409 https://doi.org/10.1007/BF02967439
  6. Parajuly SS, Peng YL. Sonography of dermatofibrosarcoma protuberans in the skin over breast. J Med Ultrasound 2010; 18:130-135 https://doi.org/10.1016/S0929-6441(10)60018-5
  7. Lee SJ, Mahoney MC, Shaughnessy E. Dermatofibrosarcoma protuberance of the breast: imaging features and review of the literature. AJR Am J Roentgenol 2009;193:64-69 https://doi.org/10.2214/AJR.08.2141
  8. Kang DK, Jung YS, Yim H. Dermatofibrosarcoma protuberance of the breast: case report. J Korean Radiol Soc 2004; 51:103-106 https://doi.org/10.3348/jkrs.2004.51.1.103
  9. Serra-Guillen C, Llombart B, Sanmartin O. [Dermatofibrosarcoma protuberans]. Actas Dermosifiliogr 2012;103:762-777 https://doi.org/10.1016/j.ad.2011.10.007
  10. Shin YR, Kim JY, Sung MS, Jung JH. Sonographic findings of dermatofibrosarcoma protuberans with pathologic correlation. J Ultrasound Med 2008;27:269-274 https://doi.org/10.7863/jum.2008.27.2.269