대한영상의학회지 (Journal of the Korean Society of Radiology)

  • 제78권2호
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  • Pages.103-106
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  • 2018
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  • 1738-2637(pISSN)
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  • 2288-2928(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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유두종양을 닮은 유방의 유두 모양 아포크린 화생: 증례 보고

Papillary Apocrine Metaplasia of the Breast Mimicking Papillary Neoplasm: A Case Report

  • 하태양 (아주대학교 의과대학 영상의학교실) ;
  • 임현이 (아주대학교 의과대학 병리학교실) ;
  • 박선영 (아주대학교 의과대학 영상의학교실) ;
  • 강두경 (아주대학교 의과대학 영상의학교실) ;
  • 김태희 (아주대학교 의과대학 영상의학교실)
  • Ha, Taeyang (Department of Radiology, Ajou University School of Medicine) ;
  • Yim, Hyunee (Department of Pathology, Ajou University School of Medicine) ;
  • Park, Seon Young (Department of Radiology, Ajou University School of Medicine) ;
  • Kang, Doo Kyoung (Department of Radiology, Ajou University School of Medicine) ;
  • Kim, Tae Hee (Department of Radiology, Ajou University School of Medicine)
  • 투고 : 2017.07.31
  • 심사 : 2017.10.07
  • 발행 : 2018.02.01
⟨ 이전 논문 다음 논문 ⟩

초록

아포크린 화생은 유방에 생기는 양성 섬유낭종성 질환으로, 아포크린 모양을 가진 원주세포로 이루어진 늘어난 샘꽈리가 특징이다. 이러한 아포크린 형태의 세포들이 낭종 내로 유두 모양의 종괴를 형성할 수 있으며 이런 경우 유두 모양 아포크린 화생이라고 한다. 본 증례에서는 오른쪽 유방에 만져지는 종괴를 주소로 48세 여환이 내원하였다. 초음파와 자기공명 영상에서 복합낭성고형 에코를 보이는 커다란 종괴가 관찰되었다. 감별진단으로는 관내 유두종양 혹은 낭종 내 유두모양 암종이 있다. 환자는 수술을 하였고, 조직검사에서 유두 모양 아포크린 화생으로 확진되었다.

Apocrine metaplasia is a benign fibrocystic change characterized by dilated acini lined by columnar cells with apocrine features. These apocrine-like cells form papillary clumps of cells extending into the cystic space called papillary apocrine metaplasia. The researchers report a case of a 48-year-old woman who presented with a palpable mass in the right breast. Breast ultrasonography and MRI showed a large complex cystic and solid mass. A differential diagnosis included intraductal papilloma or intracystic papillary carcinoma. She underwent surgery and the final diagnosis was papillary apocrine metaplasia.

키워드

참고문헌

  1. Durham JR, Fechner RE. The histologic spectrum of apocrine lesions of the breast. Am J Clin Pathol 2000;113(5 Suppl 1):S3-S18
  2. Page DL, Dupont WD, Jensen RA. Papillary apocrine change of the breast: associations with atypical hyperplasia and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 1996;5:29-32
  3. Godfrey SE. Is fibrocystic disease of the breast precancerous? Arch Pathol Lab Med 1986;110:991
  4. Warner JK, Kumar D, Berg WA. Apocrine metaplasia: mammographic and sonographic appearances. AJR Am J Roentgenol 1998;170:1375-1379 https://doi.org/10.2214/ajr.170.5.9574619
  5. Wellings SR, Jensen HM, Marcum RG. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 1975;55: 231-273
  6. Berg WA. Sonographically depicted breast clustered microcysts: is follow-up appropriate? AJR Am J Roentgenol 2005; 185:952-959 https://doi.org/10.2214/AJR.04.0929
  7. Ferguson MJ. Intracystic mural nodules of the breast: benign versus malignant; a multidisciplinary imaging and management approach. J Med Radiat Sci 2015;62:163-167 https://doi.org/10.1002/jmrs.104
  8. Kushwaha AC, O'Toole M, Sneige N, Stelling CB, Dryden MJ. Mammographic-pathologic correlation of apocrine metaplasia diagnosed using vacuum-assisted stereotactic core-needle biopsy: our 4-year experience. AJR Am J Roentgenol 2003;180:795-798 https://doi.org/10.2214/ajr.180.3.1800795
  9. diFlorio-Alexander RM, Marotti JD, Bond JS, Schwab MC, Memoli VA, Wells WA, et al. Breast MRI-detected cystic apocrine metaplasia: imaging features with microvessel analysis and histologic correlation. AJR Am J Roentgenol 2015;204:211-218 https://doi.org/10.2214/AJR.14.12869
  10. Stavros AT, Rapp CL, Parker SH. Breast ultrasound. Philadelphia, PA: Lippincott Williams & Wilkins 2004

피인용 문헌

  1. Mixed Invasive Apocrine Papillary/Micropapillary Carcinoma of the Breast: Another Brick in the Triple-Negative Wall vol.29, pp.4, 2018, https://doi.org/10.1177/1066896920954920