The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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New synergistic efficacy of combination of romiplostim and steroid in refractory immune thrombocytopenia patients

  • Yoon, Jun Seok (Department of Internal Medicine, Kyungpook National University Hospital) ;
  • Lee, Yoo Jin (Department of Hematology/Oncology, Kyungpook National University Hospital) ;
  • Baek, Dong Won (Department of Internal Medicine, Kyungpook National University Hospital) ;
  • Park, Hye Young (Department of Internal Medicine, Kyungpook National University Hospital) ;
  • Park, Bo Eun (Department of Internal Medicine, Kyungpook National University Hospital) ;
  • Moon, Joon Ho (Department of Hematology/Oncology, Kyungpook National University Hospital) ;
  • Sohn, Sang Kyun (Department of Hematology/Oncology, Kyungpook National University Hospital)
  • Received : 2015.07.31
  • Accepted : 2015.11.01
  • Published : 2018.03.01
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Abstract

Keywords

References

  1. Kuter DJ, Bussel JB, Newland A, et al. Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy. Br J Haematol 2013;161:411-423. https://doi.org/10.1111/bjh.12260
  2. Okazuka K, Masuko M, Matsuo Y, et al. Successful treatment of severe newly diagnosed immune thrombocytopenia involving an alveolar hemorrhage with combination therapy consisting of romiplostim, rituximab and vincristine. Intern Med 2013;52:1239-1242. https://doi.org/10.2169/internalmedicine.52.0080
  3. Anwer F, Yun S, Nair A, Ahmad Y, Krishnadashan R, Deeg HJ. Severe refractory immune thrombocytopenia successfully treated with high-dose pulse cyclophosphamide and eltrombopag. Case Rep Hematol 2015;2015:583451.
  4. Amgen Inc. Nplate [package insert]. Thousand Oaks: Amgen Inc., 2011.
  5. Takedatsu H, Yoshimoto K, Okamura T, et al. Determination of thrombopoietin-derived peptides recognized by both cellular and humoral immunities in healthy donors and patients with thrombocytopenia. Stem Cells 2005;23:975-982. https://doi.org/10.1634/stemcells.2004-0227

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  2. Glucocorticoids promote response to thrombopoietin-receptor agonists in refractory ITP: a case series vol.110, pp.2, 2018, https://doi.org/10.1007/s12185-019-02638-6