DOI QR코드

DOI QR Code

Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success

  • Yoo, Jung-Wan (Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Lee, Seung Jun (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Lee, Jong Deog (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kim, Ho Cheol (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University Hospital)
  • 투고 : 2016.05.12
  • 심사 : 2016.10.13
  • 발행 : 2018.03.01

초록

Background/Aims: Both diaphragmatic excursion and change in muscle thickening are measured using ultrasonography (US) to assess diaphragm function and mechanical ventilation weaning outcomes. However, which parameter can better predict successful extubation remains to be determined. The aim of this study was to compare the clinical utility of these two diaphragmatic parameters to predict extubation success. Methods: This study included patients subjected to extubation trial in the medical or surgical intensive care unit of a university-affiliated hospital from May 2015 through February 2016. Diaphragm excursion and percent of thickening change (${\Delta}tdi%$tdi%) were measured using US within 24 hours before extubation. Results: Sixty patients were included, and 78.3% (47/60) of these patients were successfully extubated, whereas 21.7% (13/60) were not. The median degree of excursion was greater in patients with extubation success than in those with extubation failure (1.65 cm vs. 0.8 cm, p < 0.001). Patients with extubation success had a greater ${\Delta}tdi%$ than those with extubation failure (42.1% vs. 22.5%, p = 0.03). The areas under the receiver operating curve for excursion and ${\Delta}tdi%$ were 0.836 (95% confidence interval [CI], 0.717 to 0.919) and 0.698 (95% CI, 0.566 to 0.810), respectively (p = 0.017). Conclusions: Diaphragm excursion seems more accurate than a change in the diaphragm thickness to predict extubation success.

키워드

참고문헌

  1. Epstein SK, Ciubotaru RL, Wong JB. Effect of failed extubation on the outcome of mechanical ventilation. Chest 1997;112:186-192. https://doi.org/10.1378/chest.112.1.186
  2. Epstein SK. Decision to extubate. Intensive Care Med 2002;28:535-546. https://doi.org/10.1007/s00134-002-1268-8
  3. McCool FD, Tzelepis GE. Dysfunction of the diaphragm. N Engl J Med 2012;366:932-942. https://doi.org/10.1056/NEJMra1007236
  4. Heunks LM, Doorduin J, van der Hoeven JG. Monitoring and preventing diaphragm injury. Curr Opin Crit Care 2015;21:34-41. https://doi.org/10.1097/MCC.0000000000000168
  5. Matamis D, Soilemezi E, Tsagourias M, et al. Sonographic evaluation of the diaphragm in critically ill patients: technique and clinical applications. Intensive Care Med 2013;39:801-810. https://doi.org/10.1007/s00134-013-2823-1
  6. Kim WY, Suh HJ, Hong SB, Koh Y, Lim CM. Diaphragm dysfunction assessed by ultrasonography: influence on weaning from mechanical ventilation. Crit Care Med 2011;39:2627-2630. https://doi.org/10.1097/CCM.0b013e3182266408
  7. DiNino E, Gartman EJ, Sethi JM, McCool FD. Diaphragm ultrasound as a predictor of successful extubation from mechanical ventilation. Thorax 2014;69:423-427.
  8. Cohn D, Benditt JO, Eveloff S, McCool FD. Diaphragm thickening during inspiration. J Appl Physiol (1985) 1997;83:291-296. https://doi.org/10.1152/jappl.1997.83.1.291
  9. Boles JM, Bion J, Connors A, et al. Weaning from mechanical ventilation. Eur Respir J 2007;29:1033-1056. https://doi.org/10.1183/09031936.00010206
  10. Artime CA, Hagberg CA. Tracheal extubation. Respir Care 2014;59:991-1002. https://doi.org/10.4187/respcare.02926
  11. Thille AW, Harrois A, Schortgen F, Brun-Buisson C, Brochard L. Outcomes of extubation failure in medical intensive care unit patients. Crit Care Med 2011;39:2612- 2618. https://doi.org/10.1097/CCM.0b013e3182282a5a
  12. Frutos-Vivar F, Esteban A, Apezteguia C, et al. Outcome of reintubated patients after scheduled extubation. J Crit Care 2011;26:502-509. https://doi.org/10.1016/j.jcrc.2010.12.015
  13. Yang KL, Tobin MJ. A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation. N Engl J Med 1991;324:1445-1450. https://doi.org/10.1056/NEJM199105233242101
  14. Lee KH, Hui KP, Chan TB, Tan WC, Lim TK. Rapid shallow breathing (frequency-tidal volume ratio) did not predict extubation outcome. Chest 1994;105:540-543. https://doi.org/10.1378/chest.105.2.540
  15. Demoule A, Jung B, Prodanovic H, et al. Diaphragm dysfunction on admission to the intensive care unit: prevalence, risk factors, and prognostic impact: a prospective study. Am J Respir Crit Care Med 2013;188:213-219. https://doi.org/10.1164/rccm.201209-1668OC
  16. Doorduin J, van Hees HW, van der Hoeven JG, Heunks LM. Monitoring of the respiratory muscles in the critically ill. Am J Respir Crit Care Med 2013;187:20-27. https://doi.org/10.1164/rccm.201206-1117CP
  17. Sarwal A, Walker FO, Cartwright MS. Neuromuscular ultrasound for evaluation of the diaphragm. Muscle Nerve 2013;47:319-329. https://doi.org/10.1002/mus.23671
  18. Boon AJ, Sekiguchi H, Harper CJ, et al. Sensitivity and specificity of diagnostic ultrasound in the diagnosis of phrenic neuropathy. Neurology 2014;83:1264-1270. https://doi.org/10.1212/WNL.0000000000000841
  19. Boussuges A, Gole Y, Blanc P. Diaphragmatic motion studied by m-mode ultrasonography: methods, reproducibility, and normal values. Chest 2009;135:391-400. https://doi.org/10.1378/chest.08-1541
  20. Valette X, Seguin A, Daubin C, et al. Diaphragmatic dysfunction at admission in intensive care unit: the value of diaphragmatic ultrasonography. Intensive Care Med 2015;41:557-559. https://doi.org/10.1007/s00134-014-3636-6
  21. Mariani LF, Bedel J, Gros A, et al. Ultrasonography for screening and follow-up of diaphragmatic dysfunction in the ICU: a pilot study. J Intensive Care Med 2016;31:338-343. https://doi.org/10.1177/0885066615583639
  22. Goligher EC, Laghi F, Detsky ME, et al. Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med 2015;41:642-649. https://doi.org/10.1007/s00134-015-3687-3
  23. Ferrari G, De Filippi G, Elia F, Panero F, Volpicelli G, Apra F. Diaphragm ultrasound as a new index of discontinuation from mechanical ventilation. Crit Ultrasound J 2014;6:8. https://doi.org/10.1186/2036-7902-6-8

피인용 문헌

  1. Diaphragm and weaning from mechanical ventilation: anticipation and outcome vol.13, pp.4, 2019, https://doi.org/10.4103/ejb.ejb_13_19
  2. Diaphragmatic rapid shallow breathing index for predicting weaning outcome from mechanical ventilation: Comparison with traditional rapid shallow breathing index vol.35, pp.1, 2018, https://doi.org/10.1016/j.egja.2018.10.003
  3. Evaluación del movimiento diafragmático por ultrasonografía mediante la medición del índice de excursión en perros vol.23, pp.1, 2018, https://doi.org/10.22579/20112629.542
  4. A narrative review of diaphragm ultrasound to predict weaning from mechanical ventilation: where are we and where are we heading? vol.11, pp.1, 2018, https://doi.org/10.1186/s13089-019-0117-8
  5. Prolonged Weaning: S2k Guideline Published by the German Respiratory Society vol.99, pp.11, 2018, https://doi.org/10.1159/000510085
  6. Assessment of diaphragmatic function by ultrasonography: Current approach and perspectives vol.8, pp.12, 2020, https://doi.org/10.12998/wjcc.v8.i12.2408
  7. Does it make difference to measure diaphragm function with M mode (MM) or B mode (BM)? vol.34, pp.6, 2018, https://doi.org/10.1007/s10877-019-00432-7
  8. Prediction of Loss of Muscle Mass in Sarcopenia Using Ultrasonic Diaphragm Excursion vol.2021, pp.None, 2021, https://doi.org/10.1155/2021/4754705
  9. Sonographic evaluation of diaphragmatic thickness and excursion as a predictor for successful extubation in mechanically ventilated preterm infants vol.180, pp.3, 2018, https://doi.org/10.1007/s00431-020-03805-2
  10. Point of care diaphragm ultrasound: An objective tool to predict the severity of pneumonia and outcomes in children vol.56, pp.6, 2018, https://doi.org/10.1002/ppul.25352
  11. Use of Ultrasound to Determine Changes in Diaphragm Mechanics During A Spontaneous Breathing Trial vol.36, pp.9, 2018, https://doi.org/10.1177/0885066620943164
  12. Early rehabilitation relieves diaphragm dysfunction induced by prolonged mechanical ventilation: a randomised control study vol.21, pp.1, 2018, https://doi.org/10.1186/s12890-021-01461-2
  13. Prediction of extubation outcome in critically ill patients: a systematic review and meta-analysis vol.25, pp.1, 2018, https://doi.org/10.1186/s13054-021-03802-3