Characterization of Two Site-Specific Mutations in Human Dihydrolipoamide Dehydrogenase Deteriorating the Apparent Enzyme Binding Affinities to Both Dihydrolipoamide and NAD<sup>+</sup>

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Characterization of Two Site-Specific Mutations in Human Dihydrolipoamide Dehydrogenase Deteriorating the Apparent Enzyme Binding Affinities to Both Dihydrolipoamide and NAD⁺

Kim, Hakjung (Department of Chemistry, College of Natural Science, Daegu University)

Jentoft, J. E.; Shoham, M.; Hurst, D.; Patel, M. S., Protein. Struct. Funct. Genet. 1992, 14, 88. https://doi.org/10.1002/prot.340140110
Reed, L. J., Acc. Chem. Res. 1974, 7, 40. https://doi.org/10.1021/ar50074a002
Grafakou, O.; Oexle, K.; van den Heuvel, L.; Smeets, R.; Trijbels, F.; Goebel, H. H.; Bosshard, N.; Superti-Furga, A.; Steinmann, B.; Smeitink, J. Eur. J. Pediatr. 2003, 162, 714. https://doi.org/10.1007/s00431-003-1282-z
Williams, C. H., Jr. Enzymes, 3rd ed; Boyer, P., Ed.; Academic Press: 1976; p. 89.
Laemmil, U. K. Nature 1970, 227, 680. https://doi.org/10.1038/227680a0
Yuan, L.; Cho, Y-J.; Kim, H. Bull. Korean Chem. Soc. 2009, 30, 777. https://doi.org/10.5012/bkcs.2009.30.4.777
Yamada, K.; Hara, N.; Shibata, T.; Osago, H.; Tsuchiya, M. Anal. Biochem. 2006, 352, 282. https://doi.org/10.1016/j.ab.2006.02.017
Yang, H.; Yang, T.; Baur, J. A.; Perez, E.; Matsui, T.; Carmona, J. J.; Lamming, D. W.; Souza-Pinto, N. C.; Bohr, V. A.; Rosenzweig, A.; de Cabo, R.; Sauve, A. A.; Sinclair, D. A. Cell 2007, 130, 1095. https://doi.org/10.1016/j.cell.2007.07.035
Chou, P. Y.; Fasman, G. D. Biochemistry 1974, 13, 222. https://doi.org/10.1021/bi00699a002
Zamyatin, A. A. Prog. Biophys. Mol. Biol. 1972, 24, 107. https://doi.org/10.1016/0079-6107(72)90005-3