대한치과교정학회지 (The korean journal of orthodontics)

  • 제48권3호
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  • Pages.163-171
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  • 2018
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  • 2234-7518(pISSN)
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  • 2005-372X(eISSN)
대한치과교정학회 (The Korean Association Of Orthodontists)
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Antibacterial and remineralization effects of orthodontic bonding agents containing bioactive glass

  • Kim, You-Min (Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital) ;
  • Kim, Dong-Hyun (R&D Center, Upex.med Co., Ltd.) ;
  • Song, Chang Weon (School of Materials Science and Engineering, Pusan National University) ;
  • Yoon, Seog-Young (School of Materials Science and Engineering, Pusan National University) ;
  • Kim, Se-Yeon (Department of Oral Microbiology, School of Dentistry, Pusan National University) ;
  • Na, Hee Sam (Department of Oral Microbiology, School of Dentistry, Pusan National University) ;
  • Chung, Jin (Department of Oral Microbiology, School of Dentistry, Pusan National University) ;
  • Kim, Yong-Il (Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital) ;
  • Kwon, Yong Hoon (Department of Dental Materials, Pusan National University)
  • 투고 : 2017.06.07
  • 심사 : 2017.09.01
  • 발행 : 2018.05.25
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초록

Objective: The aim of this study was to evaluate the mechanical and biological properties of orthodontic bonding agents containing silver- or zinc-doped bioactive glass (BAG) and determine the antibacterial and remineralization effects of these agents. Methods: BAG was synthesized using the alkali-mediated solgel method. Orthodontic bonding agents containing BAG were prepared by mixing BAG with flowable resin. $Transbond^{TM}$ XT (TXT) and $Charmfil^{TM}$ Flow (CF) were used as controls. Ion release, cytotoxicity, antibacterial properties, the shear bond strength, and the adhesive remnant index were evaluated. To assess the remineralization properties of BAG, micro-computed tomography was performed after pH cycling. Results: The BAG-containing bonding agents showed no noticeable cytotoxicity and suppressed bacterial growth. When these bonding agents were used, demineralization after pH cycling began approximately 200 to $300{\mu}m$ away from the bracket. On the other hand, when CF and TXT were used, all surfaces that were not covered by the adhesive were demineralized after pH cycling. Conclusions: Our findings suggest that orthodontic bonding agents containing silver- or zinc-doped BAG have stronger antibacterial and remineralization effects compared with conventional orthodontic adhesives; thus, they are suitable for use in orthodontic practice.

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참고문헌

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