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Diagnosis of Acute Leukemia from Oral Manifestation

  • Kang, Min-Hye (Department of Oral and Maxillofacial Surgery, Gachon University Gil Medical Center) ;
  • On, Dohyun (Department of Oral and Maxillofacial Surgery, Gachon University Gil Medical Center) ;
  • Kim, Jin Woo (Department of Oral and Maxillofacial Surgery, Gachon University Gil Medical Center) ;
  • Ryu, Jaeyoung (Department of Oral and Maxillofacial Surgery, Gachon University Gil Medical Center)
  • 투고 : 2018.07.28
  • 심사 : 2018.12.20
  • 발행 : 2018.12.30

초록

Leukemia is a hematological malignant disease with various clinical symptoms. Due to the fatal nature of the disease, early detection is important. Oral manifestations include ulcers and gingival enlargement with bleeding. Moreover, myeloid sarcoma or opportunistic infections may also occur. This report introduces a 31-year-old male presenting with generalized gingival enlargement with bleeding and another 81-year-old female with neoplasm on the left retromolar area. Both were diagnosed as acute monocytic leukemia. These cases implicate that gingival enlargement or mucosal lesion in the oral cavity may represent underlying systemic diseases. Related to this, it has to be reminded that making timely diagnosis and referral according to the clinical findings is crucial.

키워드

COHHB6_2018_v11n2_82_f0001.png 이미지

Fig. 1. Clinical photographs (A, frontal; B, upper occlusal; C, lower occlusal) of frst patient showing generalized gingival enlargement.

COHHB6_2018_v11n2_82_f0002.png 이미지

Fig. 2. Clinical photographs of second patient showing ulcerated proliferative lesion on left retromolar area.

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