Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Antibiotic Susceptibility Pattern and Molecular Typing By PCR-RAPD Analysis of Clinical and Environmental Isolates of Pseudomonas aeruginosa

  • Oluborode, O.B. (Department of Medical Microbiology and Parasitology, University of Lagos) ;
  • Smith, S.I. (Molecular Biology & Biotechnology Department, Nigerian Institute of Medical Research (NIMR)) ;
  • Seriki, T.A. (Department of Microbiology, University of Lagos Akoka) ;
  • Fowora, M. (Molecular Biology & Biotechnology Department, Nigerian Institute of Medical Research (NIMR)) ;
  • Ajayi, A. (Department of Microbiology, University of Lagos Akoka) ;
  • Coker, A.O. (Babcock University Teaching Hospital)
  • Received : 2018.05.22
  • Accepted : 2018.09.11
  • Published : 2018.12.28
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Abstract

Pseudomonas aeruginosa accounts for a significant proportion of nosocomial infections. This study examined the antimicrobial susceptibility pattern and clonal relatedness of P. aeruginosa isolates of clinical and environmental origin. These isolates displayed susceptibility to levofloxacin, ciprofloxacin, gentamicin, imipenem, and ceftazidime of 65.0%, 62.5%, 90.0%, 100%, and 85%, respectively. PCR-RAPD analysis of the P. aeruginosa isolates revealed marked variation. No correlation was observed between the antibiotic resistance profiles and the DNA typing patterns.

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References

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