대한후두음성언어의학회지 (Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics)

  • 제29권2호
  • /
  • Pages.83-86
  • /
  • 2018
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  • 2508-268X(pISSN)
  • /
  • 2508-5603(eISSN)
대한후두음성언어의학회 (The Korean Society of Laryngology, Phoniatrics and Logopedics. )
권호 표지

Efficacy of Calcium Hydroxyapatite in Vocal Fold Augmentation for Unilateral Vocal Fold Paralysis in Asian

  • Lee, Doh Young (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Boramae Medical Center, Seoul National University College of Medicine) ;
  • Chung, Eun-Jae (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital) ;
  • Kwon, Seong-Keun (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital)
  • 투고 : 2018.05.10
  • 심사 : 2018.10.16
  • 발행 : 2018.12.30
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초록

Background and Objectives : This study aimed to evaluate efficacy and complication of injection laryngoplasty using calcium hydroxyapatite (CaHA) for unilateral vocal fold paralysis in Asian. Materials and Methods : A prospective study was conducted on the adult patients with unilateral vocal fold paralysis from May 2015 through January 2016. Injection laryngoplasty was performed by one laryngologist. All patients underwent prospective voice evaluation using the subjective and objective comprehensive battery of assessments, before the procedure and after the procedure at 3 months, and 6 months. Results : A total of 7 patients (5 males and 2 females) were included in this study. VHI-10 was significantly decreased after injection laryngoplasty, at postoperative 6 months (p=0.031), while VAS score and MDADI showed no difference. GRBAS scale gradually decreased in 3 months and 6 months follow-up without statistical significance. Acoustic analysis revealed that jitter, shimmer, and noise-to-harmonic ratio continuously decreased from the baseline at 3 months and 6 months, although statistical significance was not attained. In the aerodynamic analysis, maximal phonation time was gradually increased at 3months and 6 months with significant difference (p=0.016, 0.031, respectively). There was no side effect associated with the procedure. Conclusion : CaHA can be safely used in Asian patients and the onset of maximal efficacy seems to be slow than other studies with Caucasian patients.

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참고문헌

  1. Rosen CA, Thekdi AA. Vocal fold augmentation with injectable calcium hydroxylapatite: short-term results. J Voice 2004;18:387-91. https://doi.org/10.1016/j.jvoice.2004.02.001
  2. Belafsky PC, Postma GN. Vocal fold augmentation with calcium hydroxylapatite. Otolaryngol Head Neck Surg 2004;131:351-4. https://doi.org/10.1016/j.otohns.2004.03.025
  3. Chhetri DK, Jahan-Parwar B, Hart SD, Bhuta SM, Berke GS. Injection laryngoplasty with calcium hydroxylapatite gel implant in an in vivo canine model. Ann Otol Rhinol Laryngol 2004;113:259-64. https://doi.org/10.1177/000348940411300402
  4. Caton T, Thibeault SL, Klemuk S, Smith ME. Viscoelasticity of hyaluronan and nonhyaluronan based vocal fold injectables: implications for mucosal versus muscle use. Laryngoscope 2007;117:516-21. https://doi.org/10.1097/MLG.0b013e31802e9291
  5. DeFatta RA, Chowdhury FR, Sataloff RT. Complications of injection laryngoplasty using calcium hydroxylapatite. J Voice 2012;26:614-8. https://doi.org/10.1016/j.jvoice.2011.08.005
  6. Won SJ, Woo SH. Calcium Hydroxylapatite Pulmonary Embolism after Percutaneous Injection Laryngoplasty. Yonsei Med J 2017;58:1245-8. https://doi.org/10.3349/ymj.2017.58.6.1245
  7. Rosen CA, Lee AS, Osborne J, Zullo T, Murry T. Development and validation of the voice handicap index-10. Laryngoscope 2004;114:1549-56. https://doi.org/10.1097/00005537-200409000-00009
  8. Kwon CH, Kim YH, Park JH, Oh BM, Han TR. Validity and reliability of the korean version of the MD anderson Dysphagia inventory for head and neck cancer patients. Ann Rehabil Med 2013;37:479-87. https://doi.org/10.5535/arm.2013.37.4.479
  9. Rosen CA, Gartner-Schmidt J, Casiano R, Anderson TD, Johnson F, Remacle M, et al. Vocal fold augmentation with calcium hydroxylapatite:twelve-month report. Laryngoscope 2009;119:1033-41. https://doi.org/10.1002/lary.20126
  10. Carroll TL, Rosen CA. Long-term results of calcium hydroxylapatite for vocal fold augmentation. Laryngoscope 2011;121:313-9. https://doi.org/10.1002/lary.21258
  11. Ford CN, Bless DM, Loftus JM. Role of injectable collagen in the treatment of glottic insufficiency: a study of 119 patients. Ann Otol Rhinol Laryngol 1992;101:237-47. https://doi.org/10.1177/000348949210100307
  12. Laccourreye O, Papon JF, Kania R, Crevier-Buchman L, Brasnu D, Hans S. Intracordal injection of autologous fat in patients with unilateral laryngeal nerve paralysis: long-term results from the patient's perspective. Laryngoscope 2003;113:541-5. https://doi.org/10.1097/00005537-200303000-00027
  13. Karpenko AN, Dworkin JP, Meleca RJ, Stachler RJ. Cymetra injection for unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol 2003;112:927-34. https://doi.org/10.1177/000348940311201103
  14. Nakayama M, Ford CN, Bless DM. Teflon vocal fold augmentation:failures and management in 28 cases. Otolaryngol Head Neck Surg 1993;109:493-8. https://doi.org/10.1177/019459989310900318
  15. Rubin HJ. Pitfalls in Treatment Od Dysphonias by Intracordal Injection of Synthetics. Laryngoscope 1965;75:1381-&.
  16. Woo SH, Son YI, Lee SH, Park JJ, Kim JP. Comparative Analysis on the Efficiency of the Injection Laryngoplasty Technique Using Calcium Hydroxyapatite (CaHA): The Thyrohyoid Approach Versus the Cricothyroid Approach. Journal of Voice 2013;27:236-41. https://doi.org/10.1016/j.jvoice.2012.11.001
  17. Kwon TK, Lee JE, Cha WJ, Song CM, Sung MW, Kim KH. Serial computed tomographic and positron emission tomographic properties of injection material used for vocal fold augmentation. Laryngoscope 2013;123(10):2491-6. https://doi.org/10.1002/lary.24017
  18. Chhetri DK, Jahan-Parwar B, Hart SD, Bhuta SM, Berke GS. Injection laryngoplasty with calcium hydroxylapatite gel implant in an in vivo canine model. Ann Oto Rhinol Laryn 2004;113:259-64. https://doi.org/10.1177/000348940411300402