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A Study on Jaundice Computer-aided Diagnosis Algorithm using Scleral Color based Machine Learning

  • Jeong, Jin-Gyo (Undergraduate, Department of Biomedical Engineering, Keimyung University) ;
  • Lee, Myung-Suk (Tabula Rasa College, Keimyung University)
  • Received : 2018.09.20
  • Accepted : 2018.11.12
  • Published : 2018.12.31

Abstract

This paper proposes a computer-aided diagnostic algorithm in a non-invasive way. Currently, clinical diagnosis of jaundice is performed through blood sampling. Unlike the old methods, the non-invasive method will enable parents to measure newborns' jaundice by only using their mobile phones. The proposed algorithm enables high accuracy and quick diagnosis through machine learning. In here, we used the SVM model of machine learning that learned the feature extracted through image preprocessing and we used the international jaundice research data as the test data set. As a result of applying our developed algorithm, it took about 5 seconds to diagnose jaundice and it showed a 93.4% prediction accuracy. The software is real-time diagnosed and it minimizes the infant's pain by non-invasive method and parents can easily and temporarily diagnose newborns' jaundice. In the future, we aim to use the jaundice photograph of the newborn babies' data as our test data set for more accurate results.

Keywords

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Fig. 1. Machine Learning Procedures

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Fig. 2. Eye Segmentation Algorithm

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Fig. 3 Eye estimation result

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Fig. 5. Iris segmentation & Sclera segmentation algorithm

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Fig. 7. SVM classification result of jaundice diagnosis

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Fig. 8. Diagnosis of jaundice system GUI

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Fig. 4. (a) imfill function (b) bwareaopen function (c) imopen function

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Fig. 6. (a) Hough transform result (b) Sclera segmentation result

Table 1. Variations for feature extraction[13]

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References

  1. Stoll BJ, Kliegman RM. Jaundice and hyperbilirubinemia in the newborn. In : Behrman RE, Kliegman RM, Jenson HB, editors. Nelson Textbook of Pediatrics. 17th ed. Philadelphia : WB Saunders Co, p.592-599, 2004.
  2. American Academy of Pediatrics. Subcommittee on Hyperbilirubinemia Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, p.297-316, 2004.
  3. Sllee. Neonatal Jaundice, Korean Journal of Pediatrics, 49(1), 2006.
  4. Hsahn. Textbook of pediatrics. 8th ed. Seoul : Daehan Printing & Publishing Co, p.343, 2004.
  5. Maisels MJ. Neonatal jaundice. In : Avery GB, editor. Neonatology. 2nd ed. Philadelphia : JB Lippincott, p.484, 1981.
  6. Horiguchi T, Bauer C. Ethnic differences in neonatal jaundice; comparison of Japanese and Caucasian newborn infants. Am J Obstet Gynecol p.71-74, 1975.
  7. Maisels MJ. Jaundice. In : MacDonald MG, Mullett MD, Seshia MMK, editors. Avery's Neonatology; pathophysiology & management of the newborn. 6th ed. Philadelphia : Lippincott Williams & Wilkins, p.768-846, 2005.
  8. Charalambos N., Alkistis A., Stefanos L., et al. A comparison between transcutaneous and total serum bilirubin in healthy-term greek neonates with clinical jaundice. Prague Med Rep. 115(1-2), pp.33-42, 2014. https://doi.org/10.14712/23362936.2014.4
  9. Lilian de Greef, Mayank Goel, Min Joon Seo, et al. BiliCam: Using Mobile Phones to Monitor Newborn Jaundice. Proceedings of the 2014 ACM International Joint Conference on Pervasive and Ubiquitous Compution, ACM Press, 2014.
  10. E. Alpaydin, "Introduction to Machine Learning," MIT Press: Cambridge, MA, 2004.
  11. G. Kitagawa, "The two-filter formula for smoothing and an implementation of the Gaussian-sum smoother," Ann. Inst. Stat. Math., 46, pp.605-623, 1994. https://doi.org/10.1007/BF00773470
  12. Lei Xu, Erkki Oja, Randomized Hough transform (RHT): basic mechanisms, algorithms, and computational complexities, CVGIP: Image Understanding, 57(2), p.131-154, 1993. https://doi.org/10.1006/ciun.1993.1009
  13. Alex Mariakakis , Megan A. Banks, Lauren Phillipi, Lei Yu, James Taylor, Shwetak N. Patel, BiliScreen: Smartphone-Based Scleral Jaundice Monitoring for Liver and Pancreatic Disorders, Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies, 1(2), p.1-26, 2017.