대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)

  • 제31권1호
  • /
  • Pages.99-121
  • /
  • 2018
  • /
  • 1229-4292(pISSN)
  • /
  • 2508-3619(eISSN)
대한한방부인과학회 (The Society of Korean Medicine Obstetrics and Gynecology)
권호 표지
DOI QR코드

DOI QR Code

항문생식기 헤르페스에 대한 한의학적 치료의 국내외 연구동향 분석

A Review of the Effect of Korean Medicine on Genital Herpes

  • 투고 : 2018.01.26
  • 심사 : 2018.02.14
  • 발행 : 2018.02.23
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives: Genital herpes is common disease in gynecological field. Although various treatment options such as herbal medicine, acupuncture, moxibustion are used in genital herpes, there is not enough evidence about the treatment options. This study is to prove the efficacy of oriental medicine on genital herpes by investigating papers and suggest direction of future research. Method: We searched for papers which had both genital herpes and oriental medicine from Cochrane, Pubmed, Scopus, CNKI, Oasis, Korean traditional knowledge portal, Journal of Korean Obstetrics & Gynecology up to November 2017. After searching papers, we classified according to the study design and analyzed selected studies. Results: Sixteen papers were finally selected. Four papers are laboratory studies with Hartley guinea pig with recurrent genital herpes. Twelve papers are clinical trials which includes one single group trial, one controlled trial, ten randomized controlled trials. All of the studies have shown that herbal medicine is effective in improving the symptom of genital herpes and decreasing the recurrent rate of genital herpes and also has immunoregulatory effect. Conclusions: This study shows that herbal medicine could be a good treatment option for genital herpes. However, more well-designed clinical studies and laboratory studies will be needed.

키워드

참고문헌

  1. Korean Society of Obstetrics and Gynecology. Gynecology 5th edition. Seoul:Koryo medical. 2015:166.
  2. Johnston C, Corye L. Current Concepts for genital heres simplex virus infection: diagnostics and pathogenesis of genital tract shedding. Clinical Microbiology reviews. 2016;29(1):149-61. https://doi.org/10.1128/CMR.00043-15
  3. Healthcare Bigdata Hub. Genital herpes [cited 2016]. Available from:URL: http://opendata.hira.or.kr/op/opc/olap3thDsInfo.do.
  4. Ahn SG, et al. Common Skin Disease 3rd edition. Seoul:Jungwoo. 2015:227-88.
  5. Spruance SL, et al. Application of a topical immune response modifier, resiquimod gel, to modify the recurrence rate of recurrent genital herpes: a pilot study. The journal of infectious diseases. 2001;184(2):196-200. https://doi.org/10.1086/322007
  6. Fan RQ, et al. Antiviral effect of antivirus capsule containing chinese medicinal herbs on guinea pig model of genital herpes and cell culture. Chin J Dermatol. 2001;34(3):198-201.
  7. Yang ZB, et al. Efficacy of traditional chinese medicine huangbaiye on the recurrent genital herpes model of guinea pigs. Chin J Derm Venereol. 2004;18(4):204-7.
  8. Lin K, et al. Effects of a traditional chinese medicine, Longdanxiegan fromula granule, on toll-like receptor pathway in female guinea pigs with recurrent genital herpes, Taiwanese Journal of Obstetrics & Gynecology. 2016;55(2):220-8. https://doi.org/10.1016/j.tjog.2015.12.016
  9. Yang L, Chang Y, Zhang M. The effect of herb xiangju capsules on guinea pig mode with initial genital herpes. Western journal of traditional chinese medicine. 2017;30(9):19-21.
  10. Zheng YC, Xuan GW, Li HY. Effect of antivirus capsule on quality of life of patients with recurrent genital herpes. Journal of Guangzhou university of chinese medicine. 2007;24(6):462-5.
  11. Chen FX, Wang L, Lin XF. Curative effect of traditional chinese medicine of detoxification decoction for nourishing ying and strengthening body resistance combined with thymopeptide entericcoated tablets on the treatment of recurrent genital herpes. Acta medicinae sinica. 2015;28(5):83-5.
  12. Yu JB, et al. Immune modulatory and therapeutical effect of Shenqi tablet accessory therapy in treating recurrent genital herpes. Journal of integrated traditional chinese and western medicine. 2001;21(11):831-3.
  13. Tan CM. Clinical study of effect of Fuzhengjiedutang on recurrent genital herpes. Journal of Jilin traditional chinese medicine. 2004;24(7):27-8.
  14. Liu RY, et al. Study on effect of chinese medicine on recurrent genital herpes and immunoregulatory effect. Chinese archives of traditional chinese medicine. 2004;22(9):1696-7.
  15. Yang Y, Wang JP, Guo ZW. Effect of herpes simplex decoction on recurrent genital herpes and cellular immune function in patients. Journal of Chengdu university. 2006;29(1):22-4.
  16. Yu H. Therapeutic effect of traditional chinese medicine and acyclovir on male recurrent genital herpes. Journal of practical traditional chinese medicine. 2008;24(2):787-8.
  17. Xia F. Clinical observation of traditional chinese medicine on recurrent genital herpes. Master's degree of Hubei university of traditional chinese medicine. 2008.
  18. Shi YJ, et al. Clinical study on treatment of recurrent genital herpes by huangqi fuzheng decoction. Journal of integrated traditional chinese and western medicine. 2008;28(3):222-4.
  19. Cheng GM. Synergetic effect of selfprescribed decoction eliminating herpes in treatment of recurrent genital herpes. J South Med Univ. 2010;30(6):1422-4.
  20. Xie ZY, Zhou Y. Clinical study of traditional chinese medicine on recurrent genital herpes. Journal of asia-pacific traditional medicine. 2015;11(20):90-1.
  21. Liao MY, et al. Therapeutic Effect of Chinese Herbal Medicine Compound for Recurrent Genital Herpes and Its Effect on Serum Th17/Treg Cells. Journal of Guangzhou University of Traditional Chinese Medicine. 2017;34(4):510-3.
  22. Groves MJ. Genital herpes: a review. American family physician. 2016;93(11):928-34.
  23. Gupta R, Warren T, Wald A. Genital herpes. Lancet. 2007;9605(370):2127-37.
  24. Perry CM, Wagstaff AJ. Famciclovir: A review of its pharmacological properties and therapeutic efficacy in herpes virus infections. Drugs. 1995;50(2):396-415. https://doi.org/10.2165/00003495-199550020-00011
  25. Perry CM, Faulds D. Valaciclovir: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpes virus infections. Drugs. 1996;52(5):754-72. https://doi.org/10.2165/00003495-199652050-00009
  26. Workowski KA, Bolan GA. Centers for Disease Control and Prevention Sexually transmitted diseases treatment guidelines 2015. MMWR Recomm Rep. 2015;61(8):759-62.
  27. Heo J. Donguibogam. Seoul:Hanmi medical. 2008:478-90.
  28. Kim CM, et al. Encyclopedia of Chinese medicine. Seoul:JungDam. 1997:70, 2625, 4429, 4504, 4860, 5013, 5055, 4404.