DOI QR코드

DOI QR Code

Therapeutic lumbar facet joint nerve blocks in the treatment of chronic low back pain: cost utility analysis based on a randomized controlled trial

  • Manchikanti, Laxmaiah (Pain Management Center of Paducah) ;
  • Pampati, Vidyasagar (Pain Management Center of Paducah) ;
  • Kaye, Alan D. (LSU Health Science Center) ;
  • Hirsch, Joshua A. (Massachusetts General Hospital and Harvard Medical School)
  • Received : 2017.05.08
  • Accepted : 2017.10.12
  • Published : 2018.01.01

Abstract

Background: Related to escalating health care costs and the questionable effectiveness of multiple interventions including lumbar facet joint interventions, cost effectiveness or cost utility analysis has become the cornerstone of evidence-based medicine influencing coverage decisions. Methods: Cost utility of therapeutic lumbar facet joint nerve blocks in managing chronic low back pain was performed utilizing data from a randomized, double-blind, controlled trial with a 2-year follow-up, with direct payment data from 2016. Based on the data from surgical interventions, utilizing the lowest proportion of direct procedural costs of 60%, total cost utility per quality adjusted life year (QALY) was determined by multiplying the derived direct cost at 1.67. Results: Patients in this trial on average received $5.6{\pm}2.6$ procedures over a period of 2 years, with average relief over a period of 2 years of $82.8{\pm}29.6$ weeks with $19{\pm}18.77$ weeks of improvement per procedure. Procedural cost for one-year improvement in quality of life showed USD $2,654.08. Estimated total costs, including indirect costs and drugs with multiplication of direct costs at 1.67, showed a cost of USD $4,432 per QALY. Conclusions: The analysis of therapeutic lumbar facet joint nerve blocks in the treatment of chronic low back pain shows clinical effectiveness and cost utility at USD $2,654.08 for the direct costs of the procedures, and USD $4,432 for the estimated overall cost per one year of QALY, in chronic persistent low back pain non-responsive to conservative management.

Keywords

References

  1. Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, et al. An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician 2013; 16: S49-283.
  2. Boswell MV, Manchikanti L, Kaye AD, Bakshi S, Gharibo CG, Gupta S, et al. A best-evidence systematic appraisal of the diagnostic accuracy and utility of facet (zygapophysial) joint injections in chronic spinal pain. Pain Physician 2015; 18: E497-533.
  3. Simopoulos TT, Manchikanti L, Gupta S, Aydin SM, Kim CH, Solanki D, et al. Systematic review of the diagnostic accuracy and therapeutic effectiveness of sacroiliac joint interventions. Pain Physician 2015; 18: E713-56.
  4. Manchikanti L, Hirsch JA, Falco FJ, Boswell MV. Management of lumbar zygapophysial (facet) joint pain. World J Orthop 2016; 7: 315-37. https://doi.org/10.5312/wjo.v7.i5.315
  5. Manchikanti L, Kaye AD, Boswell MV, Bakshi S, Gharibo CG, Grami V, et al. A systematic review and best evidence synthesis of the effectiveness of therapeutic facet joint interventions in managing chronic spinal pain. Pain Physician 2015; 18: E535-82.
  6. Furlan AD, Yazdi F, Tsertsvadze A, Gross A, Van Tulder M, Santaguida L, et al. A systematic review and meta-analysis of efficacy, cost-effectiveness, and safety of selected complementary and alternative medicine for neck and low-back pain. Evid Based Complement Alternat Med 2012; 2012: 953139.
  7. Tosteson AN, Skinner JS, Tosteson TD, Lurie JD, Andersson GB, Berven S, et al. The cost effectiveness of surgical versus nonoperative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT). Spine (Phila Pa 1976) 2008; 33: 2108-15. https://doi.org/10.1097/BRS.0b013e318182e390
  8. Malter AD, Larson EB, Urban N, Deyo RA. Costeffectiveness of lumbar discectomy for the treatment of herniated intervertebral disc. Spine (Phila Pa 1976) 1996; 21: 1048-54. https://doi.org/10.1097/00007632-199605010-00011
  9. Tosteson AN, Lurie JD, Tosteson TD, Skinner JS, Herkowitz H, Albert T, et al. Surgical treatment of spinal stenosis with and without degenerative spondylolisthesis: cost-effectiveness after 2 years. Ann Intern Med 2008; 149: 845-53. https://doi.org/10.7326/0003-4819-149-12-200812160-00003
  10. Taylor RS, Ryan J, O'Donnell R, Eldabe S, Kumar K, North RB. The cost-effectiveness of spinal cord stimulation in the treatment of failed back surgery syndrome. Clin J Pain 2010; 26: 463-9. https://doi.org/10.1097/AJP.0b013e3181daccec
  11. Manchikanti L, Falco FJ, Pampati V, Cash KA, Benyamin RM, Hirsch JA. Cost utility analysis of caudal epidural injections in the treatment of lumbar disc herniation, axial or discogenic low back pain, central spinal stenosis, and post lumbar surgery syndrome. Pain Physician 2013; 16: E129-43.
  12. Manchikanti L, Helm S 2nd, Pampati V, Racz GB. Cost utility analysis of percutaneous adhesiolysis in managing pain of post-lumbar surgery syndrome and lumbar central spinal stenosis. Pain Pract 2015; 15: 414-22. https://doi.org/10.1111/papr.12195
  13. Kumar K, Rizvi S, Bishop S, Tang W. Cost impact of intrathecal polyanalgesia. Pain Med 2013; 14: 1569-84. https://doi.org/10.1111/pme.12204
  14. Kumar K, Rizvi S. Cost-effectiveness of spinal cord stimulation therapy in management of chronic pain. Pain Med 2013; 14: 1631-49. https://doi.org/10.1111/pme.12146
  15. Manchikanti L, Pampati V, Benyamin RM, Hirsch JA. Cost utility analysis of lumbar interlaminar epidural injections in the treatment of lumbar disc herniation, central spinal stenosis, and axial or discogenic low back pain. Pain Physician 2017; 20: 219-28.
  16. Kepler CK, Wilkinson SM, Radcliff KE, Vaccaro AR, Anderson DG, Hilibrand AS, et al. Cost-utility analysis in spine care: a systematic review. Spine J 2012; 12: 676-90. https://doi.org/10.1016/j.spinee.2012.05.011
  17. Indrakanti SS, Weber MH, Takemoto SK, Hu SS, Polly D, Berven SH. Value-based care in the management of spinal disorders: a systematic review of cost-utility analysis. Clin Orthop Relat Res 2012; 470: 1106-23. https://doi.org/10.1007/s11999-011-2141-2
  18. National Institute for Health and Clinical Excellence (GB). Guide to the methods of technology appraisal. London, National Institute for Health and Clinical Excellence. 2008.
  19. Dagenais S, Roffey DM, Wai EK, Haldeman S, Caro J. Can cost utility evaluations inform decision making about interventions for low back pain? Spine J 2009; 9: 944-57. https://doi.org/10.1016/j.spinee.2009.07.007
  20. Hong J, Reed C, Novick D, Happich M. Costs associated with treatment of chronic low back pain: an analysis of the UK General Practice Research Database. Spine (Phila Pa 1976) 2013; 38: 75-82. https://doi.org/10.1097/BRS.0b013e318276450f
  21. Wielage R, Bansal M, Wilson K, Klein R, Happich M. Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective. Spine (Phila Pa 1976) 2013; 38: 936-46. https://doi.org/10.1097/BRS.0b013e31828264f9
  22. Dagenais S, Haldeman S, Polatin PB. It is time for physicians to embrace cost-effectiveness and cost utility analysis research in the treatment of spinal pain. Spine J 2005; 5: 357-60. https://doi.org/10.1016/j.spinee.2005.03.001
  23. Fritz JM, Kim M, Magel JS, Asche CV. Cost-effectiveness of primary care management with or without early physical therapy for acute low back pain: economic evaluation of a randomized clinical trial. Spine (Phila Pa 1976) 2017; 42: 285-90. https://doi.org/10.1097/BRS.0000000000001729
  24. Childs JD, Fritz JM, Wu SS, Flynn TW, Wainner RS, Robertson EK, et al. Implications of early and guideline adherent physical therapy for low back pain on utilization and costs. BMC Health Serv Res 2015; 15: 150. https://doi.org/10.1186/s12913-015-0830-3
  25. Fritz JM, Brennan GP, Hunter SJ, Magel JS. Initial management decisions after a new consultation for low back pain: implications of the usage of physical therapy for subsequent health care costs and utilization. Arch Phys Med Rehabil 2013; 94: 808-16. https://doi.org/10.1016/j.apmr.2013.01.008
  26. Fritz JM, Childs JD, Wainner RS, Flynn TW. Primary care referral of patients with low back pain to physical therapy: impact on future health care utilization and costs. Spine (Phila Pa 1976) 2012; 37: 2114-21. https://doi.org/10.1097/BRS.0b013e31825d32f5
  27. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008; 8: 8-20. https://doi.org/10.1016/j.spinee.2007.10.005
  28. Luo X, Pietrobon R, Sun SX, Liu GG, Hey L. Estimates and patterns of direct health care expenditures among individuals with back pain in the United States. Spine (Phila Pa 1976) 2004; 29: 79-86. https://doi.org/10.1097/01.BRS.0000105527.13866.0F
  29. Brealey S, Burton K, Coulton S, Farrin A, Garratt A, Harvey E, et al. UK Back pain Exercise And Manipulation (UK BEAM) trial--national randomised trial of physical treatments for back pain in primary care: objectives, design and interventions [ISRCTN32683578]. BMC Health Serv Res 2003; 3: 16. https://doi.org/10.1186/1472-6963-3-16
  30. Derby R, Melnik I, Lee JE, Lee SH. Cost comparisons of various diagnostic medial branch block protocols and medial branch neurotomy in a private practice setting. Pain Med 2013; 14: 378-91. https://doi.org/10.1111/pme.12026
  31. Rivero-Arias O, Gray A, Frost H, Lamb SE, Stewart-Brown S. Cost-utility analysis of physiotherapy treatment compared with physiotherapy advice in low back pain. Spine (Phila Pa 1976) 2006; 31: 1381-7. https://doi.org/10.1097/01.brs.0000218486.13659.d5
  32. Critchley DJ, Ratcliffe J, Noonan S, Jones RH, Hurley MV. Effectiveness and cost-effectiveness of three types of physiotherapy used to reduce chronic low back pain disability: a pragmatic randomized trial with economic evaluation. Spine (Phila Pa 1976) 2007; 32: 1474-81. https://doi.org/10.1097/BRS.0b013e318067dc26
  33. Manchikanti L, Benyamin RM, Falco FJ, Kaye AD, Hirsch JA. Do epidural injections provide short- and long-term relief for lumbar disc herniation? A systematic review. Clin Orthop Relat Res 2015; 473: 1940-56. https://doi.org/10.1007/s11999-014-3490-4
  34. Manchikanti L, Nampiaparampil DE, Manchikanti KN, Falco FJ, Singh V, Benyamin RM, et al. Comparison of the efficacy of saline, local anesthetics, and steroids in epidural and facet joint injections for the management of spinal pain: a systematic review of randomized controlled trials. Surg Neurol Int 2015; 6: S194-235. https://doi.org/10.4103/2152-7806.156598
  35. Manchikanti L, Manchikanti KN, Gharibo CG, Kaye AD. Efficacy of percutaneous adhesiolysis in the treatment of lumbar post surgery syndrome. Anesth Pain Med 2016; 6: e26172.
  36. Manchikanti L, Knezevic NN, Boswell MV, Kaye AD, Hirsch JA. Epidural injections for lumbar radiculopathy and spinal stenosis: a comparative systematic review and metaanalysis. Pain Physician 2016; 19: E365-410.
  37. Kaye AD, Manchikanti L, Abdi S, Atluri S, Bakshi S, Benyamin R, et al. Efficacy of epidural injections in managing chronic spinal pain: a best evidence synthesis. Pain Physician 2015; 18: E939-1004.
  38. Manchikanti L, Pampati V, Benyamin RM, Boswell MV. Analysis of efficacy differences between caudal and lumbar interlaminar epidural injections in chronic lumbar axial discogenic pain: local anesthetic alone vs. local combined with steroids. Int J Med Sci 2015; 12: 214-22. https://doi.org/10.7150/ijms.10870
  39. Manchikanti L, Cash KA, McManus CD, Damron KS, Pampati V, Falco FJ. A randomized, double-blind controlled trial of lumbar interlaminar epidural injections in central spinal stenosis: 2-year follow-up. Pain Physician 2015; 18: 79-92.
  40. Helm S 2nd, Racz GB, Gerdesmeyer L, Justiz R, Hayek SM, Kaplan ED, et al. Percutaneous and endoscopic adhesiolysis in managing low back and lower extremity pain: a systematic review and meta-analysis. Pain Physician 2016; 19: E245-82.
  41. Manchikanti L, Nampiaparampil DE, Candido KD, Bakshi S, Grider JS, Falco FJ, et al. Do cervical epidural injections provide long-term relief in neck and upper extremity pain? A systematic review. Pain Physician 2015; 18: 39-60.
  42. Manchikanti L, Singh V, Pampati V, Falco FJ, Hirsch JA. Comparison of the efficacy of caudal, interlaminar, and transforaminal epidural injections in managing lumbar disc herniation: is one method superior to the other? Korean J Pain 2015; 28: 11-21. https://doi.org/10.3344/kjp.2015.28.1.11
  43. Manchikanti L, Hirsch JA, Kaye AD, Boswell MV. Cervical zygapophysial (facet) joint pain: effectiveness of interventional management strategies. Postgrad Med 2016; 128: 54-68. https://doi.org/10.1080/00325481.2016.1105092
  44. Manchikanti L, Kaye AD, Manchikanti K, Boswell M, Pampati V, Hirsch J. Efficacy of epidural injections in the treatment of lumbar central spinal stenosis: a systematic review. Anesth Pain Med 2015; 5: e23139.
  45. Grider JS, Manchikanti L, Carayannopoulos A, Sharma ML, Balog CC, Harned ME, et al. Effectiveness of spinal cord stimulation in chronic spinal pain: a systematic review. Pain Physician 2016; 19: E33-54.
  46. Manchikanti L, Staats PS, Nampiaparampil DE, Hirsch JA. What is the role of epidural injections in the treatment of lumbar discogenic pain: a systematic review of comparative analysis with fusion. Korean J Pain 2015; 28: 75-87. https://doi.org/10.3344/kjp.2015.28.2.75
  47. Chou R, Hashimoto R, Friedly J, Fu R, Dana T, Sullivan S, et al. Pain management injection therapies for low back pain. Rockville (MD), Agency for Healthcare Research and Quality. 2015.
  48. Manchikanti L, Pampati V, Hirsch JA. Utilization of interventional techniques in managing chronic pain in medicare population from 2000 to 2014: an analysis of patterns of utilization. Pain Physician 2016; 19: E531-46.
  49. Manchikanti L, Hirsch JA, Pampati V, Boswell MV. Utilization of facet joint and sacroiliac joint interventions in medicare population from 2000 to 2014: explosive growth continues! Curr Pain Headache Rep 2016; 20: 58. https://doi.org/10.1007/s11916-016-0588-2
  50. Manchikanti L, Pampati V, Hirsch JA. Retrospective cohort study of usage patterns of epidural injections for spinal pain in the US fee-for-service medicare population from 2000 to 2014. BMJ Open 2016; 6: e013042. https://doi.org/10.1136/bmjopen-2016-013042
  51. Rajaee SS, Bae HW, Kanim LE, Delamarter RB. Spinal fusion in the United States: analysis of trends from 1998 to 2008. Spine (Phila Pa 1976) 2012; 37: 67-76. https://doi.org/10.1097/BRS.0b013e31820cccfb
  52. Manchikanti L, Kaye AM, Kaye AD. Current state of opioid therapy and abuse. Curr Pain Headache Rep 2016; 20: 34. https://doi.org/10.1007/s11916-016-0564-x
  53. Hirsch JA, Chandra RV, Pampati V, Barr JD, Brook AL, Manchikanti L. Analysis of vertebral augmentation practice patterns: a 2016 update. J Neurointerv Surg 2016 [in press].
  54. Manchikanti L, Kaye AM, Knezevic NN, McAnally H, Slavin K, Trescot AM, et al. Responsible, safe, and effective prescription of opioids for chronic non-cancer pain: American society of interventional pain physicians (ASIPP) guidelines. Pain Physician 2017; 20: S3-92.
  55. Martin BI, Turner JA, Mirza SK, Lee MJ, Comstock BA, Deyo RA. Trends in health care expenditures, utilization, and health status among US adults with spine problems, 1997-2006. Spine (Phila Pa 1976) 2009; 34: 2077-84. https://doi.org/10.1097/BRS.0b013e3181b1fad1
  56. Dieleman JL, Baral R, Birger M, Bui AL, Bulchis A, Chapin A, et al. US spending on personal health care and public health, 1996-2013. JAMA 2016; 316: 2627-46. https://doi.org/10.1001/jama.2016.16885
  57. Bae HW, Rajaee SS, Kanim LE. Nationwide trends in the surgical management of lumbar spinal stenosis. Spine (Phila Pa 1976) 2013; 38: 916-26. https://doi.org/10.1097/BRS.0b013e3182833e7c
  58. Manchikanti L, Pampati V, Falco FJ, Hirsch JA. An updated assessment of utilization of interventional pain management techniques in the Medicare population: 2000-2013. Pain Physician 2015; 18: E115-27.
  59. Hirsch JA, Leslie-Mazwi TM, Patel AB, Rabinov JD, Gonzalez RG, Barr RM, et al. MACRA: background, opportunities and challenges for the neurointerventional specialist. J Neurointerv Surg 2016; 8: 868-74. https://doi.org/10.1136/neurintsurg-2015-011952
  60. Manchikanti L, Staats PS, Boswell MV, Hirsch JA. Analysis of the carrot and stick policy of repeal of the sustainable growth rate formula: the good, the bad, and the ugly. Pain Physician 2015; 18: E273-92.
  61. Hirsch JA, Leslie-Mazwi TM, Nicola GN, Bhargavan- Chatfield M, Seidenwurm DJ, Silva E, et al. PQRS and the MACRA: value-based payments have moved from concept to reality. AJNR Am J Neuroradiol 2016; 37: 2195-200. https://doi.org/10.3174/ajnr.A4936
  62. Manchikanti L, Hammer M, Benyamin RM, Hirsch JA. Physician quality reporting system (PQRS) for interventional pain management practices: challenges and opportunities. Pain Physician 2016; 19: E15-32.
  63. Manchikanti L, Helm Ii S, Benyamin RM, Hirsch JA. Meritbased incentive payment system (MIPS): harsh choices for interventional pain management physicians. Pain Physician 2016; 19: E917-34.
  64. Manchikanti L, Helm Ii S, Calodney AK, Hirsch JA. Meritbased incentive payment system: meaningful changes in the final rule brings cautious optimism. Pain Physician 2017; 20: E1-12.
  65. Pinto RZ, Maher CG, Ferreira ML, Hancock M, Oliveira VC, McLachlan AJ, et al. Epidural corticosteroid injections in the management of sciatica: a systematic review and metaanalysis. Ann Intern Med 2012; 157: 865-77. https://doi.org/10.7326/0003-4819-157-12-201212180-00564
  66. Friedly JL, Comstock BA, Turner JA, Heagerty PJ, Deyo RA, Sullivan SD, et al. A randomized trial of epidural glucocorticoid injections for spinal stenosis. N Engl J Med 2014; 371: 11-21. https://doi.org/10.1056/NEJMoa1313265
  67. Manchikanti L, Candido KD, Kaye AD, Boswell MV, Benyamin RM, Falco FJ, et al. Randomized trial of epidural injections for spinal stenosis published in the New England Journal of Medicine: further confusion without clarification. Pain Physician 2014; 17: E475-88.
  68. Chou R, Hashimoto R, Friedly J, Fu R, Bougatsos C, Dana T, et al. Epidural corticosteroid injections for radiculopathy and spinal stenosis: a systematic review and meta-analysis. Ann Intern Med 2015; 163: 373-81. https://doi.org/10.7326/M15-0934
  69. Boswell MV, Manchikanti L. Appropriate design, methodological quality assessment, and clinically relevant outcomes are essential to determine the therapeutic role of epidural injections for low back pain and radiculopathy. Evid Based Med 2016; 21: 89. https://doi.org/10.1136/eb-2015-110310
  70. Manchikanti L, Singh V, Falco FJ, Cash KA, Pampati V. Lumbar facet joint nerve blocks in managing chronic facet joint pain: one-year follow-up of a randomized, doubleblind controlled trial: Clinical Trial NCT00355914. Pain Physician 2008; 11: 121-32.
  71. Manchikanti L, Singh V, Falco FJ, Cash KA, Pampati V. Evaluation of lumbar facet joint nerve blocks in managing chronic low back pain: a randomized, double-blind, controlled trial with a 2-year follow-up. Int J Med Sci 2010; 7: 124-35.
  72. Whitehurst DG, Lewis M, Yao GL, Bryan S, Raftery JP, Mullis R, et al. A brief pain management program compared with physical therapy for low back pain: results from an economic analysis alongside a randomized clinical trial. Arthritis Rheum 2007; 57: 466-73. https://doi.org/10.1002/art.22606
  73. Johnson RE, Jones GT, Wiles NJ, Chaddock C, Potter RG, Roberts C, et al. Active exercise, education, and cognitive behavioral therapy for persistent disabling low back pain: a randomized controlled trial. Spine (Phila Pa 1976) 2007; 32: 1578-85. https://doi.org/10.1097/BRS.0b013e318074f890
  74. Manchikanti L, Hirsch JA. Repeal and replace of affordable care: a complex, but not an impossible task. Pain Physician 2016; 19: E1109-13.
  75. Manchikanti L, Helm Ii S, Benyamin RM, Hirsch JA. A critical analysis of obamacare: affordable care or insurance for many and coverage for few? Pain Physician 2017; 20: 111-38.
  76. Manchikanti L, Hirsch JA. Obamacare 2012: prognosis unclear for interventional pain management. Pain Physician 2012; 15: E629-40.
  77. Hirsch JA, Barr RM, McGinty G, Nicola GN, Schaefer PW, Silva E 3rd, et al. Affordable care 2014: a tale of two boards. J Neurointerv Surg 2014; 6: 718-20. https://doi.org/10.1136/neurintsurg-2014-011322
  78. Manchikanti L, Hirsch JA. Patient protection and affordable care act of 2010: a primer for neurointerventionalists. J Neurointerv Surg 2012; 4: 141-6. https://doi.org/10.1136/neurintsurg-2011-010036
  79. Hirsch JA, Leslie-Mazwi TM, Barr RM, McGinty G, Nicola GN, Patel AB, et al. The Burwell roadmap. J Neurointerv Surg 2016; 8: 544-6. https://doi.org/10.1136/neurintsurg-2015-011706
  80. Porter ME, Teisberg EO. Redefining health care: creating value-based competition on results. Boston (MA), Harvard Business School Press. 2006.
  81. Manchikanti L, Helm Ii S, Singh V, Hirsch JA. Accountable interventional pain management: a collaboration among practitioners, patients, payers, and government. Pain Physician 2013; 16: E635-70.
  82. Manchikanti L, Falco FJ, Benyamin RM, Gharibo CG, Candido KD, Hirsch JA. Epidural steroid injections safety recommendations by the Multi-Society Pain Workgroup (MPW): more regulations without evidence or clarification. Pain Physician 2014; 17: E575-88.
  83. Manchikanti L, Hirsch JA. Neurological complications associated with epidural steroid injections. Curr Pain Headache Rep 2015; 19: 482.
  84. Manchikanti L, Benyamin RM. Key safety considerations when administering epidural steroid injections. Pain Manag 2015; 5: 261-72. https://doi.org/10.2217/pmt.15.17
  85. Manchikanti L, Falco FJ. Safeguards to prevent neurologic complications after epidural steroid injections: analysis of evidence and lack of applicability of controversial policies. Pain Physician 2015; 18: E129-38.
  86. Goossens ME, Evers SM, Vlaeyen JW, Rutten-van Molken MP, van der Linden SM. Principles of economic evaluation for interventions of chronic musculoskeletal pain. Eur J Pain 1999; 3: 343-53. https://doi.org/10.1016/S1090-3801(99)90016-2
  87. Hopwood M. Outcomes assessment in pain management. In: Pain management. Edited by Abram SE. Philadelphia (PA), Churchill-Livingstone. 1998, pp 14.1-14.11.
  88. Manchikanti L, Kaye AD, Hirsch JA. Proposed medicare physician payment schedule for 2017: impact on interventional pain management practices. Pain Physician 2016; 19: E935-55.
  89. Manchikanti L, Singh V, Hirsch JA. Facility payments for interventional pain management procedures: impact of proposed rules. Pain Physician 2016; 19: E957-84.

Cited by

  1. Comparison of effectiveness for fluoroscopic cervical interlaminar epidural injections with or without steroid in cervical post-surgery syndrome vol.31, pp.4, 2018, https://doi.org/10.3344/kjp.2018.31.4.277
  2. Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data vol.26, pp.4, 2018, https://doi.org/10.1007/s10787-018-0493-x
  3. Comparative Analysis of Utilization of Epidural Procedures in Managing Chronic Pain in the Medicare Population vol.44, pp.3, 2019, https://doi.org/10.1097/BRS.0000000000002785
  4. Superior articular process cross-sectional area is a new sensitive parameter for the diagnosis of lumbar central canal spinal stenosis vol.13, pp.None, 2018, https://doi.org/10.2147/cia.s172355
  5. Optimal cut-off points of lumbar pedicle thickness as a morphological parameter to predict lumbar spinal stenosis syndrome: a retrospective study vol.11, pp.None, 2018, https://doi.org/10.2147/jpr.s168990
  6. Utilization Patterns of Facet Joint Interventions in Managing Spinal Pain: a Retrospective Cohort Study in the US Fee-for-Service Medicare Population vol.23, pp.10, 2018, https://doi.org/10.1007/s11916-019-0816-7
  7. Treatment of Discogenic Low Back Pain: Current Treatment Strategies and Future Options-a Literature Review vol.23, pp.11, 2018, https://doi.org/10.1007/s11916-019-0821-x
  8. Usefulness of the Inferior Articular Process’s Cross-Sectional Area as a Morphological Parameter for Predicting Central Lumbar Spinal Stenosis vol.9, pp.1, 2020, https://doi.org/10.3390/jcm9010214
  9. Evaluation of Cost-Utility of Thoracic Interlaminar Epidural Injections vol.24, pp.3, 2018, https://doi.org/10.1007/s11916-020-0838-1
  10. Utilization of Vertebral Augmentation Procedures in the USA: a Comparative Analysis in Medicare Fee-for-Service Population Pre- and Post-2009 Trials vol.24, pp.5, 2018, https://doi.org/10.1007/s11916-020-00850-2
  11. Does Epidural Bupivacaine with or Without Steroids Provide Long-Term Relief? A Systematic Review and Meta-analysis vol.24, pp.6, 2018, https://doi.org/10.1007/s11916-020-00859-7
  12. A Comprehensive Update on the Treatment and Management of Postdural Puncture Headache vol.24, pp.6, 2020, https://doi.org/10.1007/s11916-020-00860-0
  13. The Role of the Cannabinoid System in Pain Control: Basic and Clinical Implications vol.24, pp.7, 2020, https://doi.org/10.1007/s11916-020-00873-9
  14. A Comprehensive Review of the Treatment and Management of Myofascial Pain Syndrome vol.24, pp.8, 2020, https://doi.org/10.1007/s11916-020-00877-5
  15. A Comprehensive Review of the Celiac Plexus Block for the Management of Chronic Abdominal Pain vol.24, pp.8, 2020, https://doi.org/10.1007/s11916-020-00878-4
  16. Lessons for Better Pain Management in the Future: Learning from the Past vol.9, pp.2, 2018, https://doi.org/10.1007/s40122-020-00170-8