DOI QR코드

DOI QR Code

Muscle-specific receptor tyrosine kinase (MuSK) myasthenia gravis associated with castleman disease

  • Received : 2016.11.08
  • Accepted : 2016.12.20
  • Published : 2017.01.31

Abstract

Muscle specific tyrosine kinase (MuSK) myasthenia gravis (MG) is a rare subtype of MG, which is immunologically distinct and differential therapeutic response. Though MG is often associated with other autoimmune disorders or malignancy, concurrence of other disease and MuSK MG has been infrequently reported. We present a patient of MuSK MG associated with multicentric Castelman disease.

Keywords

References

  1. Dispenzieri A, Armitage JO, Loe MJ, Geyer SM, Allred J, Camoriano JK, et al. The clinical spectrum of Castleman's disease. Am J Hematol 2012;87:997-1002. https://doi.org/10.1002/ajh.23291
  2. Day JR, Bew D, Ali M, Dina R, Smith PL. Castleman's disease associated with myasthenia gravis. Ann Thorac Surg 2003;75:1648-1650. https://doi.org/10.1016/S0003-4975(02)04963-9
  3. Chorzelski T, Hashimoto T, Maciejewska B, Amagai M, Anhalt GJ, Jablonska S. Paraneoplastic pemphigus associated with Castleman tumor, myasthenia gravis and bronchiolitis obliterans. J Am Acad Dermatol 1999;41:393-400. https://doi.org/10.1016/S0190-9622(99)70111-8
  4. Wang HW, Pittaluga S, Jaffe ES. Multicentric Castleman disease: where are we now? Semin Diagn Pathol 2016;33:294-306. https://doi.org/10.1053/j.semdp.2016.05.006
  5. Cheuk W, Chan JK. Lymphadenopathy of IgG4-related disease: an underdiagnosed and overdiagnosed entity. Semin Diagn Pathol 2012;29:226-234. https://doi.org/10.1053/j.semdp.2012.07.001
  6. Hurst RL, Gooch CL. Muscle-specific receptor tyrosine kinase (MuSK) myasthenia gravis. Curr Neurol Neurosci Rep 2016;16:61. https://doi.org/10.1007/s11910-016-0668-z
  7. Oh SJ. Muscle-Specific receptor tyrosine kinase antibody positive myasthenia gravis current status. J Clin Neurol 2009;5:53-64. https://doi.org/10.3988/jcn.2009.5.2.53
  8. Sylvester J, Purdie G, Slee M, Gray JX, Burnet S, Koblar S. Muscle-specific kinase antibody positive myaesthenia gravis and multiple sclerosis co-presentation: a case report and literature review. J Neuroimmunol 2013;264:130-133. https://doi.org/10.1016/j.jneuroim.2013.08.016